Bos taurus (cow): 280817 Help Entry 280817            CDS       T01008                                  Symbol HK1 Name (RefSeq) hexokinase-1   KO K00844   hexokinase [EC:2.7.1.1] Organism bta  Bos taurus (cow) Pathway bta00010   Glycolysis / Gluconeogenesis bta00051   Fructose and mannose metabolism bta00052   Galactose metabolism bta00500   Starch and sucrose metabolism bta00520   Amino sugar and nucleotide sugar metabolism bta00524   Neomycin, kanamycin and gentamicin biosynthesis bta01100   Metabolic pathways bta01200   Carbon metabolism bta01250   Biosynthesis of nucleotide sugars bta04066   HIF-1 signaling pathway bta04910   Insulin signaling pathway bta04930   Type II diabetes mellitus bta04973   Carbohydrate digestion and absorption bta05230   Central carbon metabolism in cancer Module bta_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate bta_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc bta_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:bta00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     280817 (HK1)    00051 Fructose and mannose metabolism     280817 (HK1)    00052 Galactose metabolism     280817 (HK1)    00500 Starch and sucrose metabolism     280817 (HK1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     280817 (HK1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     280817 (HK1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     280817 (HK1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     280817 (HK1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     280817 (HK1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     280817 (HK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     280817 (HK1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:bta04131]     280817 (HK1) Enzymes [BR:bta01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      280817 (HK1) Membrane trafficking [BR:bta04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     280817 (HK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 UvrD-helicase Motif Other DBs NCBI-GeneID:  280817 NCBI-ProteinID:  NP_001012686 Ensembl:  ENSBTAG00000012380 VGNC:  29864 UniProt:  Q5W5U3 LinkDB All DBs Position 28:25655622..25768164 Genome browser AA seq 917 aa AA seqDB search MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLLDIMNRFKKEMKNGLSRDFNPTAT VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQAVHMESEVYDTPENIMH GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSRIDEAILITWTKRFKASGV EGTDVVKLLDKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME ELRHIDLVEGDEGRMCVNTEWGAFGDDGALEDIRTEFDREIDRGSLNPGKQLFEKMVSGM YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG VEPSDDDCVAVQHVCTIVSFRSANLVAATLGAILSRLRDNKGTPRLRTTVGVDGSLYKTH PQYSRRFHKTLRRLVPDCDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFSLT KEMLLEVKKRMRAEMELGLGKQTHDKAVVKMLPSFVRSTPDGTENGDFLALDLGGTNFRV LLVKIRSGKKRSVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPKMPLGF TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVVNDTVG TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVETLEGNQGQMCINMEWGAFGDNGCLDD IRTIYDKLVDEFSLNSGKQRYEKMISGMYLGEIVRNILIDFAKRGFLFRGQISEPLKTRG LFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG AALITAVGVRLRQEMSS NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgccgcgcagctcctagcttattacttcaccgaactgaaggatgaccaagtcaaa aagattgacaagtatctctatgccatgcggctctctgatgaaactctgttagatatcatg aatcgtttcaaaaaggagatgaagaatggcctctcccgggattttaatccgacagccaca gtcaagatgttgccaacgtttgtaaggtctattcccgatggctcagaaaagggagatttc atcgccctggatcttggcggatcttcctttcgaattctgcgggtgcaggtgaatcacgag cagaaccaggctgttcatatggagtctgaggtttacgacaccccggagaacatcatgcat ggcagtggaagccagctttttgatcacgtcgctgagtgcctgggagacttcatggagaaa aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccttgtcggcaa tccagaatagacgaggccatcctgatcacctggacaaagagatttaaagcgagcggcgtg gagggaactgatgtggtgaagctgcttgacaaagccatcaaaaagcgtggggactatgat gccaacattgtggctgtggtgaacgacacggtggggaccatgatgacctgtggctacgac gaccagcagtgtgaagtcggcctcatcattggtaccggcaccaacgcgtgctacatggag gagctgagacacatcgacctggtggagggcgacgaggggaggatgtgcgtcaacaccgag tggggggcctttggggacgacggggccctggaggacatccgcaccgagttcgaccgggag atagaccgggggtcgctcaaccccgggaagcagctgtttgagaagatggtcagtggcatg tacctgggcgagctggtccgactgatcctggtcaagatggccaaggagggcctcttattt gaagggcggatcaccccagagctgctcaccagagggaagtttaacaccagtgacgtgtcg gccatcgaaaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga gtggagccgtctgatgacgactgtgttgcggttcagcatgtgtgcaccatcgtctcattt cgctctgccaacctggtggcggcgaccctgggtgccatcttgagccgccttcgagataac aagggcacgcccaggctgcggaccacggttggtgtcgacgggtccctttacaagacgcac ccacagtattctcggcgtttccacaagactctgcggcgcttggtacccgactgtgatgtg cgtttcctcctctccgagagcggcagtggcaagggggccgccatggtgactgccgtggcc taccgcctggctgagcagcaccggcagatagaggagaccctggcccacttcagcctcacc aaggaaatgctgctggaggtgaaaaagcggatgcgggctgagatggaattggggctgggc aagcagacgcatgacaaggctgtggtcaagatgttgccctccttcgtccggagcactcct gatgggactgagaacggtgacttcttggccctggatcttggaggaacgaatttccgcgtc ctgctggtgaaaatccgtagtgggaaaaagagatcggtggaaatgcacaataagatctac gccattcccattgaaatcatgcagggcactggggaggagctgtttgaccacatcgtttcc tgcatctctgacttcctggactacatgggcatcaagggccctaaaatgcctctgggcttc acattttcgtttccctgcaagcagacgagcttagatgcgggtatcttaatcacctggacc aaaggttttaaggcaaccgactgcgtggggcatgatgtagcaaccttactgagggaggcg ataaaaaggagagaggaatttgacctggatgtggtggctgtggtcaacgacacggtgggc accatgatgacctgtgcttatgaggagcccacctgcgaggttggactcatcgtagggact ggcagcaatgcctgctacatggaggaaatgaaaaacgtcgagacgctagaaggaaaccag ggacaaatgtgtatcaacatggagtggggtgcctttggggacaacgggtgtctggatgat atcagaacaatctatgacaaactggtggatgagttttctctaaactctgggaagcaaagg tatgagaagatgatcagcggtatgtacctgggtgagattgtccgcaacatcttgatcgac ttcgccaagaggggcttcctcttccgggggcagatctctgagccgctgaagacccggggc ctctttcagaccaagtatctctctcagatcgagagcgaccgattagcgctgctgcaggtc cgggccatcctccagcagctgggcctgaacagcacgtgcgacgacagtatcctcgtgaag accgtgtgtggggtggtgtccaagagggcggcgcagctgtgtggcgcaggcatggctgct gtggtggataagatccgcgaaaacagggggctggaccgcctcaacgtgactgtgggcgtg gacgggacgctctacaagcttcatccgcacttctccagaatcatgcaccaaaccgtgaag gaactgtcaccaaagtgtaatgtgtccttcctcttatctgaagacggcagcggcaaggga gccgccctcatcacagcggtgggcgttcggctccggcaagaaatgagcagctaa

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