Bos taurus (cow): 280943 Help Entry 280943            CDS       T01008                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism bta  Bos taurus (cow) Pathway bta01523   Antifolate resistance bta04010   MAPK signaling pathway bta04060   Cytokine-cytokine receptor interaction bta04061   Viral protein interaction with cytokine and cytokine receptor bta04064   NF-kappa B signaling pathway bta04071   Sphingolipid signaling pathway bta04150   mTOR signaling pathway bta04210   Apoptosis bta04217   Necroptosis bta04350   TGF-beta signaling pathway bta04380   Osteoclast differentiation bta04612   Antigen processing and presentation bta04620   Toll-like receptor signaling pathway bta04621   NOD-like receptor signaling pathway bta04622   RIG-I-like receptor signaling pathway bta04625   C-type lectin receptor signaling pathway bta04640   Hematopoietic cell lineage bta04650   Natural killer cell mediated cytotoxicity bta04657   IL-17 signaling pathway bta04660   T cell receptor signaling pathway bta04664   Fc epsilon RI signaling pathway bta04668   TNF signaling pathway bta04920   Adipocytokine signaling pathway bta04930   Type II diabetes mellitus bta04931   Insulin resistance bta04932   Non-alcoholic fatty liver disease bta04933   AGE-RAGE signaling pathway in diabetic complications bta04936   Alcoholic liver disease bta04940   Type I diabetes mellitus bta05010   Alzheimer disease bta05014   Amyotrophic lateral sclerosis bta05020   Prion disease bta05022   Pathways of neurodegeneration - multiple diseases bta05132   Salmonella infection bta05133   Pertussis bta05134   Legionellosis bta05135   Yersinia infection bta05140   Leishmaniasis bta05142   Chagas disease bta05143   African trypanosomiasis bta05144   Malaria bta05145   Toxoplasmosis bta05146   Amoebiasis bta05152   Tuberculosis bta05160   Hepatitis C bta05161   Hepatitis B bta05163   Human cytomegalovirus infection bta05164   Influenza A bta05165   Human papillomavirus infection bta05166   Human T-cell leukemia virus 1 infection bta05168   Herpes simplex virus 1 infection bta05169   Epstein-Barr virus infection bta05170   Human immunodeficiency virus 1 infection bta05171   Coronavirus disease - COVID-19 bta05205   Proteoglycans in cancer bta05310   Asthma bta05321   Inflammatory bowel disease bta05322   Systemic lupus erythematosus bta05323   Rheumatoid arthritis bta05330   Allograft rejection bta05332   Graft-versus-host disease bta05410   Hypertrophic cardiomyopathy bta05414   Dilated cardiomyopathy bta05417   Lipid and atherosclerosis bta05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     280943 (TNF)    04350 TGF-beta signaling pathway     280943 (TNF)    04064 NF-kappa B signaling pathway     280943 (TNF)    04668 TNF signaling pathway     280943 (TNF)    04071 Sphingolipid signaling pathway     280943 (TNF)    04150 mTOR signaling pathway     280943 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     280943 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     280943 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     280943 (TNF)    04217 Necroptosis     280943 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     280943 (TNF)    04620 Toll-like receptor signaling pathway     280943 (TNF)    04621 NOD-like receptor signaling pathway     280943 (TNF)    04622 RIG-I-like receptor signaling pathway     280943 (TNF)    04625 C-type lectin receptor signaling pathway     280943 (TNF)    04650 Natural killer cell mediated cytotoxicity     280943 (TNF)    04612 Antigen processing and presentation     280943 (TNF)    04660 T cell receptor signaling pathway     280943 (TNF)    04657 IL-17 signaling pathway     280943 (TNF)    04664 Fc epsilon RI signaling pathway     280943 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     280943 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     280943 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     280943 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     280943 (TNF)    05170 Human immunodeficiency virus 1 infection     280943 (TNF)    05161 Hepatitis B     280943 (TNF)    05160 Hepatitis C     280943 (TNF)    05171 Coronavirus disease - COVID-19     280943 (TNF)    05164 Influenza A     280943 (TNF)    05168 Herpes simplex virus 1 infection     280943 (TNF)    05163 Human cytomegalovirus infection     280943 (TNF)    05169 Epstein-Barr virus infection     280943 (TNF)    05165 Human papillomavirus infection     280943 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     280943 (TNF)    05135 Yersinia infection     280943 (TNF)    05133 Pertussis     280943 (TNF)    05134 Legionellosis     280943 (TNF)    05152 Tuberculosis     280943 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     280943 (TNF)    05144 Malaria     280943 (TNF)    05145 Toxoplasmosis     280943 (TNF)    05140 Leishmaniasis     280943 (TNF)    05142 Chagas disease     280943 (TNF)    05143 African trypanosomiasis     280943 (TNF)   09163 Immune disease    05310 Asthma     280943 (TNF)    05322 Systemic lupus erythematosus     280943 (TNF)    05323 Rheumatoid arthritis     280943 (TNF)    05321 Inflammatory bowel disease     280943 (TNF)    05330 Allograft rejection     280943 (TNF)    05332 Graft-versus-host disease     280943 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     280943 (TNF)    05014 Amyotrophic lateral sclerosis     280943 (TNF)    05020 Prion disease     280943 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     280943 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     280943 (TNF)    05418 Fluid shear stress and atherosclerosis     280943 (TNF)    05410 Hypertrophic cardiomyopathy     280943 (TNF)    05414 Dilated cardiomyopathy     280943 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     280943 (TNF)    04940 Type I diabetes mellitus     280943 (TNF)    04936 Alcoholic liver disease     280943 (TNF)    04932 Non-alcoholic fatty liver disease     280943 (TNF)    04931 Insulin resistance     280943 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     280943 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     280943 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:bta04052]     280943 (TNF)    00536 Glycosaminoglycan binding proteins [BR:bta00536]     280943 (TNF) Cytokines and neuropeptides [BR:bta04052]  Cytokines   Tumor necrosis fators    280943 (TNF) Glycosaminoglycan binding proteins [BR:bta00536]  Heparan sulfate / Heparin   Cytokines    280943 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  280943 NCBI-ProteinID:  NP_776391 BGD-bta:  BT10618 VGNC:  36153 UniProt:  Q06599 LinkDB All DBs Position 23:complement(27716170..27718943) Genome browser AA seq 234 aa AA seqDB search MSTKSMIRDVELAEEVLSEKAGGPQGSRSCLCLSLFSFLLVAGATTLFCLLHFGVIGPQR EEQSPGGPSINSPLVQTLRSSSQASSNKPVAHVVADINSPGQLRWWDSYANALMANGVKL EDNQLVVPADGLYLIYSQVLFRGQGCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHR ETPEWAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPDYLDYAESGQVYFGIIAL NT seq 705 nt NT seq  +upstreamnt  +downstreamnt atgagcaccaaaagcatgatccgggatgtggagctggcggaggaggtgctctccgagaaa gcagggggcccccagggctccagaagttgcttgtgcctcagcctcttctccttcctcctg gttgcaggagccaccacgctcttctgcctgctgcacttcggggtaatcggcccccagagg gaagagcagtccccaggtggcccctccatcaacagccctctggttcaaacactcaggtcc tcttctcaagcctcaagtaacaagccggtagcccacgttgtagccgacatcaactctccg gggcagctccggtggtgggactcgtatgccaatgccctcatggccaacggtgtgaagctg gaagacaaccagctggtggtgcctgctgacgggctttacctcatctactcacaggtcctc ttcaggggccaaggctgcccttccacccccttgttcctcacccacaccatcagccgcatt gcagtctcctaccagaccaaggtcaacatcctgtctgccatcaagagcccttgccacagg gagaccccagagtgggctgaggccaagccctggtatgaacccatctaccagggaggagtc ttccagctggagaagggagatcgcctcagtgctgagatcaacctgccggactacctggac tatgccgagtctgggcaggtctactttgggatcatcgccctgtga

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