Bos taurus (cow): 281152
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Entry
281152 CDS
T01008
Symbol
FASN
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
bta
Bos taurus (cow)
Pathway
bta00061
Fatty acid biosynthesis
bta01100
Metabolic pathways
bta01212
Fatty acid metabolism
bta04152
AMPK signaling pathway
bta04910
Insulin signaling pathway
bta04936
Alcoholic liver disease
Module
bta_M00082
Fatty acid biosynthesis, initiation
bta_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
281152 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
281152 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
281152 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
bta01004
]
281152 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
bta04147
]
281152 (FASN)
Enzymes [BR:
bta01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
281152 (FASN)
Lipid biosynthesis proteins [BR:
bta01004
]
Fatty acid synthase
Animal type
281152 (FASN)
Exosome [BR:
bta04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
281152 (FASN)
Exosomal proteins of breast milk
281152 (FASN)
Exosomal proteins of colorectal cancer cells
281152 (FASN)
Exosomal proteins of bladder cancer cells
281152 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
KR
Thioesterase
Ketoacyl-synt_C
KAsynt_C_assoc
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
Methyltransf_12
PP-binding
adh_short
Methyltransf_23
PS-DH
Thiolase_N
DUF7080
Methyltransf_11
Methyltransf_31
Motif
Other DBs
NCBI-GeneID:
281152
NCBI-ProteinID:
NP_001012687
Ensembl:
ENSBTAG00000015980
VGNC:
28871
UniProt:
Q71SP7
LinkDB
All DBs
Position
19:50776231..50794939
Genome browser
AA seq
2513 aa
AA seq
DB search
MEEVVITGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
DASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGINPASIRGTNTGVWVGVSGSEASEAL
SRDPETLVGYSMVGCQRAMLANRLSFFFDFKGPSITLDTACSSSLLALQRAYQAIQRGEC
AMAIVGGVNIRLKPNTSVQFMKLGMLSPEGTCKFFDASGNGYCRAKAVMAILLTKKSLAR
RVYATILNAGTNTDGCKEKGVTFPSGEAQEQLISSLYKPAGLDPETLEYVEAHGTGTKVG
DPQELNGIVQALCGTRQSPLRIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
NPNPKIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILQPNSQPLPPPAPHAAL
PRLLRASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIATPSPAAMPFRGYAVLGSQGGSQ
KVQQVLAGKRPLWFICSGMGTQWRGMGLSLMRLSRFRDSILRSDEAVKPLGLQVSQLLLS
TDEAIFDDMVISFVSLTAIQIALIDLLTSMGLQPDGIIGHSLGEVACGYADGCISQEEAI
LSAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNCIDTVTISGPQASMLE
FVQQLKQEGVFAKEVRTGGMAFHSYFMDAIAPMLLQQLKKVIREPQPRSPRWLSTSIPET
QWQESLARTFSAEYNVNNLVSPVLFQEALWRVPEDAVVLEIAPHALLQAVLKRGLKSSCT
IIPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQ
TWDVPTAEDFPSGSSSSSATIYKIDINPESPDHYLVDHCIDGRIIFPGTGYLCLVWKTLA
RALDQNMEHTPVVFEDVTLHQAVILPKTGIVLLKVRLLEASCTFEVSENGNLIASGKVYQ
WEDPNPKLFDNRYGPDPATPVDPTTAIHLSRGDVYKELQLQGFNYGPYFQGILEASSEGN
TGQLLWKDNWVTFMDTMLQMSILAPSKRSLRLPTRITAIYIHPATHQQKLYTLQDKTQVA
DVVINRCLDTTVAGGIYISRIHTSVAPRHQQEQLVPILEKFCFTPHVETGCLAGNLALQE
ELQLCVGLAQALQTRVAQQGIKMVVPGLDGAQAPQEAPQQGLPRLLATACQLQLNGNLQM
EMGQILAQERALLCDDPLLSGLLNSPALKACVTLALENMTSLKMKVVLAGDGQLYSRIPT
LLNTQPLLELDYTATDRHPQALEAAQAKLQQLDITQGQWDPSDPAPSNLGGANLVVCNYA
LASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDEW
ERLFAGASLHLVALKKSFYGSVLFLCRRLAPLDSPIFLPVEDTSFQWVDSLKNILADSSS
RAVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPETDPKSLELQKVLQ
SDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQPTA
PGFQLCTIYYASLNFKRNHAGHGQAVPRRHPRNWASRNCLLGMEFSGRDASGKRVMGLVP
AEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALMVRGRMQPGETVLIHSGSG
GVGQAAIAIALSLGCRVFPLVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTAG
KGADLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSKNHPLGMAIFLKNVTFHGILLDS
LFEENNTMWQEVSTLLKAGIRKGVVQPLKRTVFPRTQAEDAFRYMAQGKHIGKVVIQVRE
EEQEAVLHGTKPTQMVALCKTFCPAHKSYIITGGLGGFGLELAHWLVERGAQKLVLTSRS
GIRTGYQARQVHEWRRQGVQVLVSTSDVSTLDGTRSLITEAAQLGPVGGIFNLAVVLRDA
MLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFEVFSSVSCGRGNAGQTNYGFAN
STMERICEKRRHDGLPGLAVQWGAIADVGLLMELKGTKDKAIGGTLPQRITSCMEVLDLF
LNQPHPVLSSFVLAEKATSRGPSGSHQDLVKAVTHILGIRDLATVNLDSSLSDLGLDSLM
GVEVRQMLEREHNLLLSMREIRQLTIHKLQEISAQAGTADELTDSTPKFGSPAQSHTQLN
LSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLATKLSIPTYGLQCTGAAP
LDSIQSLATYYIECIRQVQPEGNYRIAGYSYGACVAFEMCSQLQAQQNAGPTNNSLFLFD
GSHTFVMAYTQSYRAKLNPGCEAEAEAEAMCFFMQQFTEAEHSRVLEALLPLGDLEARVA
ATVELIVQSHAGLDRHALSFAARSFYHKLRAAEEYTPRATYHGNVTLLRAKMGSAYQEGL
GADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG
NT seq
7542 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgatcactggcatgtctgggaagctgcctgagtcggagaacctggag
gagttctgggccaatctcattggcggtgtggacatggtgacagatgatgacaggcggtgg
aaggccggactatatggcctgcctcggcggtcaggcaagctgaaggacctgtcccggttt
gacgcttccttcttcggggtccaccccaagcaggcacacaatatggacccccagctccgc
ttgctgctggaggtcacctacgaggccattgtggatgcaggcatcaacccagcttccatt
cgggggacgaacaccggtgtctgggtgggtgtgagtggctctgaggcttcagaggctctg
agccgagaccctgagaccctcgtgggctacagcatggtgggctgccagcgtgccatgttg
gccaaccgcctctccttcttctttgacttcaaagggcccagcatcaccctggacacggca
tgctcctccagcctgctggccctgcagagggcctaccaggccatccagagaggggagtgc
gccatggccattgtcggcggcgtgaacatccggctgaagcccaacacctcggtgcagttc
atgaagctgggcatgcttagccccgagggcacctgcaagtttttcgatgcatcagggaat
ggctactgccgtgcaaaggctgtaatggccatccttctgaccaagaagtccctggcccga
cgggtgtacgccaccatcctcaacgctggcaccaacacggatggctgcaaagagaaaggc
gtcaccttcccctccggagaggcacaggagcagctcatcagctccctgtataagccggcc
gggctggacccggagaccctggagtacgttgaagcccatggcaccggtaccaaggtgggc
gacccccaggagctaaacggcatcgtgcaagccctgtgtggcacccgccagagccccctg
cggattgggtccaccaagtcgaacatgggacatccggagcccgcctcagggctcgcggcg
ctggccaaggtgctgctgtccctggagcacgggctctgggcccccaacctgcacttccac
aacccaaaccccaagatcccagcactgcaggatgggcggctgcaggtggtggaccggccc
ctgcccgtcctcgggggcaacgtgggcatcaactcctttggcttcggtggctccaacgtg
cacgtcatcctccagcccaactcccagccactgccaccgcctgccccacatgccgccctg
ccccgtctgctgcgggccagtgggcgcaccctggagggtgtgcagggtctgctggagcta
ggcctccagcacagccagaacctggccttcgtgagcatgctcaatgacatcgcgaccccc
tccccagcagccatgcccttccgtggctacgccgtgctgggcagccaggggggcagccag
aaggtgcagcaggtgctggccggcaagcgcccactctggttcatctgctccggtatgggc
acacagtggcgcgggatggggctgagtctgatgcgtctgagccgcttccgcgactccatc
ctgcgctcggatgaggccgtgaagcctctgggactgcaggtgtcacagctgttgttgagc
acagacgaggccatctttgatgacatggtcatctccttcgtgagcctcactgccatccag
atcgcgctcatagacctgctgacctccatgggccttcagcccgacggcataatcgggcac
tccctgggtgaggtggcctgtggctatgccgacggctgcatctctcaggaggaggccatc
ctctctgcctactggagaggccagtgcatcaaggaggccaacatcccgcccggggccatg
gcggctgtaggcttgacctgggaggagtgtaagcagcgctgcccccctggcatcgtgcct
gcctgccacaactgcatcgacaccgtgaccatctcgggacctcaggcctccatgttggag
ttcgtgcagcagctgaagcaggagggcgtgttcgccaaggaggtgcggacgggcggcatg
gcgttccactcctacttcatggacgctatcgcccccatgctgcttcagcagctcaagaag
gtgatccgggagccccagccgcgttccccacgctggctcagcacttccatccccgagacc
cagtggcaggagagcctggcccgcaccttctcggccgagtacaacgtgaacaacctggtg
agccccgtgctgttccaggaggcgctgtggcgcgtgcccgaggacgccgtggtgctggag
atcgcaccccatgcactgctgcaggccgtcctgaagagaggcctcaagtccagctgcacc
atcatccccctgatgaagaaggaccacagggacaacctagagttcttcctcagcaacgtg
ggccagctctacctgaccggcattgacgtcaaccccaacgggctgttcccacctgtggag
ttcccagctccccggggcacccccctcatttccccccacatcaagtgggaccacagccag
acctgggatgtgcccactgctgaggacttccccagtggctccagtagctcttctgccacc
atctataagatcgacatcaaccccgagtcccctgaccactatctggtggatcactgcatc
gacggtcgcatcatcttcccgggcactggctacctgtgcctggtctggaagacactggcc
cgagccctggaccagaacatggagcacacgcctgtagtattcgaggacgtgacgctgcac
caggctgtcatcctgccgaagacagggattgtgctcctgaaagtgcggcttctggaagct
tcctgtacctttgaggtgtctgagaatggcaacctgatcgcgagcgggaaggtataccag
tgggaagatcccaaccccaagctctttgacaaccggtatggcccggaccctgcgaccccc
gtggaccccacaactgccatccacctgtcccgtggtgatgtatacaaggagctgcagctg
cagggcttcaactacggcccctacttccaaggtatccttgaggccagctccgaaggcaac
acaggccagctgctctggaaggacaactgggtgaccttcatggacaccatgctgcagatg
tctatcctggccccgagcaagcgcagcctgcgcctgcccacacgcatcaccgccatctac
atccacccggctacccaccagcagaagctgtacacgctgcaggacaagacacaagtggcc
gacgtggtaataaacaggtgtctggacaccacggtggctggcggcatctacatctcaagg
atccacacctcggtggccccccggcatcagcaggagcagctggtgcccatcctggagaag
ttctgcttcacaccgcacgtggagactgggtgcctggctgggaacctggccctgcaggag
gagctgcaactgtgtgtggggctggcacaggcactgcagaccagggtggcccagcagggg
ataaagatggtggttcctgggctggatggtgcccaggctccccaggaggccccacagcaa
ggcctgcctcggctgctggccaccgcctgccagctgcaactcaacgggaacttacagatg
gagatgggccagatcctagcccaggagagagccctgctgtgtgatgaccccctgctcagt
gggctcctcaactccccagcactcaaggcgtgcgtgacacttgccctggagaacatgacc
agcctcaagatgaaggtggtgctagctggtgacggccaactgtattcccgcatccccacg
ctgctcaacacccagcccctgctggagctggactacacagccactgaccgccacccccag
gccctggaggctgcccaggccaaattgcagcagctcgatataacccagggccagtgggac
ccctcggacccggcccccagcaacctgggtggggccaacctcgtggtgtgcaactatgcc
ttagccagcctcggtgacccggccacggctgtcggtaatatggtggctgccctcaaggag
ggaggcttcctgttgctgcacacgctgctcagaggacaccccttgggagagactgtcacc
ttcctcacttgccctgagccacaacaaggccaacggcacctcctgagccaggatgagtgg
gagcgcctgtttgctggtgcgtccctgcacctggtggccctgaagaagtccttctacggc
tcggtgctcttcctgtgccgccggctggccccgcttgacagcccaatcttcctgcctgtg
gaggacaccagcttccagtgggttgactccctgaagaacatcctggccgattcctcctcc
cgggccgtatggctcatggctgttggctgcaccacctcaggggtcgtgggcttggtgaac
tgtctccggaaagagcctgacgggcaccggattcggtgcgtcctggtgtctaacctcaac
agcacgtcccccatccctgagacagacccgaagtccttggagctgcagaaggtgctccag
agtgacctggtgatgaatgtctaccgtgatggggcctggggagcgttccgccacttccca
ctggaacaagacaagcccgaggagcagacagagcatgccttcataaatgtcctcacccga
ggggacctgtcttccatccgctgggtctgctcccctctgcgccacagccagcccacggcc
cctggcttccagctctgcaccatctattatgcctccctcaacttcaaaagaaatcatgct
ggccacgggcaagctgtcccccgacgccatcccaggaattgggcctctcggaactgcctg
ctaggcatggagttctctggccgagatgccagcgggaagcgtgtgatggggctggtaccc
gccgaaggcctggccacctccactctggtgcctcagagcttcctgtgggacgtgccttcc
aactggaccctggaggaggccgcctcggtgcccgttgtctacagcacagcctactacgcg
ctgatggtccgcgggcgcatgcagccaggcgagacggtgctcattcactcgggctccggc
ggcgtaggccaggctgccatcgccatcgccctcagcctgggctgccgtgttttcccactt
gtggggtcagccgaaaagcgggcatacctccagtccaggttcccccagctcaacgaaacc
agctttgccaactcccgggacacatcctttgagcagcatgtgctgtggcacacagccggg
aagggtgctgacctggtcctcaactccctggcggaagagaagcttcaggccagtgtgcgg
tgcctggcccagcacggtcgattcctggaaattggcaaatttgacctttccaaaaaccac
cccctgggcatggccatcttcctgaagaacgtgactttccacgggatcctactggactct
ctctttgaagaaaacaacaccatgtggcaggaagtgtcgacactgctgaaggcgggcatc
cggaagggtgtggtgcagcccctcaagcgaacagtgttccccaggacccaggcggaggac
gctttccgttacatggcccagggcaaacacatcggcaaagtggtcattcaggtacgtgag
gaagagcaggaggcggtgctgcacgggaccaaacccacccagatggtggccttgtgcaag
accttctgcccagcccacaagagctacatcatcactgggggcctgggtggctttggccta
gagctggcccactggctcgtggagcgaggggcccagaagctggtgctgacctcccgctct
gggatccgcacaggctaccaagccaggcaggtccacgagtggagacgccagggtgtgcag
gtcctggtgtccaccagcgacgtcagcacactggatggcacccggagccttatcactgag
gccgcccagcttgggcccgtgggaggcatcttcaacctggccgtggtcctgagagatgcc
atgctggataaccagacccctgagttcttccaggacgtcaacaagcccaagtacaatggc
accctgaacttggacagggtgacccgggaggcatgcccagagctggactacttcgaggtc
ttctcctccgtgagctgcgggcgtggcaatgccggccagaccaactacgggttcgccaac
tccaccatggagcgcatatgtgagaagcgtcggcacgacggcctcccaggcctcgccgtg
cagtggggtgcgattgctgacgtgggcctcctcatggagctgaagggcactaaagacaaa
gccatcggcgggacgctgccccagcgcatcacctcctgcatggaggttctagacctcttc
ctgaaccagccccaccccgtcctgagcagctttgtgttggcagagaaggctacatcccgt
ggccccagcggcagccaccaggacctcgtgaaggctgtgactcacatcctgggcatccgt
gacttggccaccgtcaacctggacagctcgctttcagaccttggcctcgactcactcatg
ggcgtggaggtgcgccagatgctggagcgtgagcacaacctgctgctgtccatgcgggaa
atccggcagctcacaatccacaagctgcaggagatttccgcgcaggctggcacagctgat
gagctgacggactccacacccaaattcggcagccctgcccaatcgcacacccagctgaac
ctgagcaccctgctggtgaaccccgagggcccgaccttgacacggctcaactcggtgcag
agctccgagcggcccctgttcctggtgcaccccatcgagggctccaccaccgtgttccac
agcctggccaccaagctcagcatccccacctatggcctacagtgtacaggagcggcaccc
ctggacagcatccagagcctggccacctactacatcgagtgcatcaggcaagtgcagcca
gaggggaactaccgcatcgctggctactcctacggggcctgcgtggctttcgagatgtgc
tcacagctgcaggcccagcagaacgctggccccacgaacaacagcctcttcctgtttgac
ggctcgcacaccttcgtgatggcctacactcagagctaccgggccaagctgaaccccggc
tgcgaggcagaggccgaggccgaggccatgtgcttcttcatgcagcagttcacggaggcg
gagcatagtagagtgctggaggccctcctgcccctcggggatctggaggcgcgtgtggca
gccaccgtcgagctgatcgtgcagagccacgcgggcctggaccggcacgcgctcagcttt
gctgcgcgttccttctaccacaagctgcgcgccgcggaggagtacacgccgcgggctacc
taccacggcaacgtgacgctgctgcgcgccaagatgggcagcgcctaccaggagggcctg
ggcgccgactacaatctgtcccaggtgtgcgacggcaaggtgtctgtacacatcatcgag
ggcgaccaccgcacgctgctggagggcagcggcctggagtccatccttagtattattcac
agctccctggccgagccgcgcgtcagcgtgcgggagggctag
DBGET
integrated database retrieval system
