Bos taurus (cow): 281530 Help Entry 281530            CDS       T01008                                  Symbol THBS1 Name (RefSeq) thrombospondin-1 precursor   KO K16857   thrombospondin 1 Organism bta  Bos taurus (cow) Pathway bta04015   Rap1 signaling pathway bta04115   p53 signaling pathway bta04145   Phagosome bta04148   Efferocytosis bta04151   PI3K-Akt signaling pathway bta04350   TGF-beta signaling pathway bta04510   Focal adhesion bta04512   ECM-receptor interaction bta04820   Cytoskeleton in muscle cells bta05144   Malaria bta05165   Human papillomavirus infection bta05205   Proteoglycans in cancer bta05206   MicroRNAs in cancer bta05219   Bladder cancer Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     281530 (THBS1)    04350 TGF-beta signaling pathway     281530 (THBS1)    04151 PI3K-Akt signaling pathway     281530 (THBS1)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     281530 (THBS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     281530 (THBS1)    04148 Efferocytosis     281530 (THBS1)   09143 Cell growth and death    04115 p53 signaling pathway     281530 (THBS1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     281530 (THBS1)   09142 Cell motility    04820 Cytoskeleton in muscle cells     281530 (THBS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     281530 (THBS1)    05205 Proteoglycans in cancer     281530 (THBS1)   09162 Cancer: specific types    05219 Bladder cancer     281530 (THBS1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     281530 (THBS1)   09174 Infectious disease: parasitic    05144 Malaria     281530 (THBS1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:bta04131]     281530 (THBS1)   09183 Protein families: signaling and cellular processes    00536 Glycosaminoglycan binding proteins [BR:bta00536]     281530 (THBS1) Membrane trafficking [BR:bta04131]  Endocytosis   Phagocytosis    Opsonins     281530 (THBS1) Glycosaminoglycan binding proteins [BR:bta00536]  Heparan sulfate / Heparin   Extracellular matrix molecules    281530 (THBS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TSP_C TSP_3 TSP_1 TSP1_spondin VWC TSP1_CFP_C EGF_3 cEGF TSP1_ADAMTS EGF_CA Laminin_G_3 Laminin_G_2 TSP1_CCN EGF Laminin_G_1 Motif Other DBs NCBI-GeneID:  281530 NCBI-ProteinID:  NP_776621 BGD-bta:  BT18365 Ensembl:  ENSBTAG00000002006 VGNC:  35828 UniProt:  Q28178 LinkDB All DBs Position 10:35209555..35225356 Genome browser AA seq 1170 aa AA seqDB search MGLAWGLGVLLLLHACGSNRIPESGGDNSVFDIFELTGAARKRSGRRLVKGPDPSSPAFR IEDANLIPPVPDKKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLAVERKDHSGQVFSVI SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSIFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVFV TLDNNVVNGSSPAIRTDYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELANELRRPPLCYHNGVQYRTGDEWTVDSCTECRCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSVTCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGKARE TKACQKDSCPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPKPQFGGKDCVGDVTENQI CNKQDCPIDGCLSNPCFAGVQCTSYPDGSWKCGACPPGYSGDGVECKDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGRGVEHATANKQVCKPRNPCTDGTHDCNKN AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLLCVANATYHCRKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDSILNERDNCQYVYNVDQKDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDQDKVPDIDDICPENVDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTSGQVRTLWHDPRHIGWKDFTAYRWHLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDS NT seq 3513 nt NT seq  +upstreamnt  +downstreamnt atggggctggcctggggactcggtgtcctgctcctgttgcatgcctgcggctccaaccgc attccagagtctgggggagacaacagtgtgtttgacatctttgaactcaccggagctgcc cgcaagcggtctgggcgccgactggtgaagggccctgacccttctagcccagctttccgc atcgaggatgccaacctgatcccccctgtgcctgacaagaagttccaagacctagtggat gctgtgcgggcggagaaaggtttcctcctcctggcctccctgaggcaaatgaagaagacc cggggtaccctgctggctgtggagcggaaagaccactctggccaggtcttcagcgtgatc tccaatggcaaggcgggcaccctggacctgagcctgaccgtgcaggggaagcagcatgtg gtgtcggtggaagaagcactcctggcgactggccagtggaagagcatcaccctgtttgtg caggaggacagggcccagctgtacatcgactgtgagaagatggagaatgcggagctggat gtccccatccagagcatcttcaccagggacctggccagcatcgccaggctccgcattgcc aaaggaggtgtcaacgacaatttccagggggtgctgcagaatgtaaggtttgtctttgga accacaccagaagacatcctcaggaacaaaggctgctccagctctaccagtgtctttgtc acccttgacaacaacgtggtgaatgggtccagccctgccatccgcaccgactacattggc cacaagacaaaggacctgcaagccatctgtggcatctcatgtgacgagctgtccagcatg gtcctggagctcaggggtctacgcaccatcgtgaccacgctgcaggacagtatccgcaaa gtgaccgaagagaacaaagagctggccaacgagctgaggaggcccccactctgctaccac aacggagtgcagtacaggactggcgacgagtggacggtggacagctgcactgagtgtcgc tgccagaactcagttaccatctgcaaaaaagtgtcctgtcccatcatgccctgctccaat gccacagttccggatggagaatgctgcccacggtgctggcccagcgactctgcagacgat ggctggtccccgtggtctgagtggacctcttgctctgtgacctgtggcaatggaatccag cagcgtggccgctcctgcgacagcctcaacaacagatgcgagggctcctctgtgcagacg cggacctgccacatccaggagtgtgacaagagatttaaacaggatggcggctggagccac tggtccccatggtcatcttgctccgtaacatgtggagacggtgtgatcacaaggatccgg ctctgcaactcccccagcccccagatgaatgggaagccatgtgagggcaaagcccgggag accaaagcctgccagaaagactcctgccccatcaatggaggctggggaccttggtcacca tgggacatctgttctgtcacctgtggaggaggggtacagaaacgtagccggctctgcaac aaccccaaaccccagtttggaggcaaggactgcgttggtgatgtgacagaaaaccagatc tgcaacaagcaggactgtcccattgacggatgcctgtccaatccctgctttgctggtgtc cagtgtaccagctaccctgatggcagctggaagtgtggtgcctgtcccccaggctatagt ggagatggagtcgagtgcaaagacgttgatgagtgcaaagaagtccctgatgcctgcttc aaccacaatggagagcacaggtgtgagaacacagaccccggctacaactgcctgccctgc ccaccgcgcttcactggctcgcagccctttggccggggcgtggaacatgccaccgccaac aagcaggtatgcaagccccgaaacccctgcacagacgggacacacgactgcaacaagaac gccaagtgcaactacctgggccactacagcgaccccatgtaccgctgcgagtgcaagcct ggctacgccggcaacggcatcatctgcggggaggacacagacctggacggctggcccaat gaggacctgctgtgcgtggccaacgcaacttaccactgcagaaaggataattgccccaac cttcccaactcagggcaggaagactatgacaaggatggaatcggcgatgcctgcgatgat gacgatgacaatgataagattccagatgacagggacaactgtccattccattacaaccca gcccagtacgactatgacagagatgacgtgggagaccgctgtgacaactgcccctacaac cacaacccagaccaggctgacacagataacaatggggaaggagacgcctgtgcagctgac attgatggggacagtatcctcaatgaacgggacaactgccagtatgtctacaatgtggac cagaaagacactgacatggacggggttggtgatcagtgtgacaactgccccctggaacac aatccagaccagctcgactctgactcggaccgcattggagacacctgtgacaacaatcag gatattgatgaagacggccaccagaacaatctggacaactgtccctacgtgcccaacgcc aaccaggctgaccatgacaaggatggcaaaggcgatgcctgtgaccatgatgacgacaat gatggcattcctgatgaccgggacaactgcaggctggtgcccaatcctgaccagaaggac tctgatggtgatggtcgaggtgatgcttgcaaagatgattttgaccaggacaaggtgcca gacattgatgacatctgtcccgaaaatgttgatatcagtgagactgatttccgccgattc cagatgattcctctagatcccaaagggacatcccagaatgaccctaactgggttgtacgc catcagggtaaagaactcgtccagactgtcaactgtgaccctggacttgctgtaggttat gacgaatttaacgccgtggacttcagtggcaccttcttcatcaacaccgagagggatgac gactatgccggctttgtgtttggctaccagtccagcagccgcttctatgttgtgatgtgg aagcaagtcactcagtcctactgggacaccaaccccacgagggctcaggggtactctgga ctttccgtgaaggttgtaaactccaccacggggcctggcgagcacctgcggaatgccctg tggcacacaggaaacacctctggccaggtgcgcacactgtggcatgaccctcgtcacatt ggctggaaagatttcactgcctacagatggcatctgagccacaggccaaagacaggtttc atcagagtggtaatgtatgaagggaagaaaatcatggctgactcaggacccatctatgac aaaacctatgctggtgggaggctaggcttgttcgtcttctctcaagaaatggtgttcttc tccgacctgaaatatgaatgcagagactcctaa

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