Bos taurus (cow): 281601 Help Entry 281601            CDS       T01008                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism bta  Bos taurus (cow) Pathway bta00230   Purine metabolism bta01100   Metabolic pathways bta01522   Endocrine resistance bta04015   Rap1 signaling pathway bta04020   Calcium signaling pathway bta04022   cGMP-PKG signaling pathway bta04024   cAMP signaling pathway bta04062   Chemokine signaling pathway bta04072   Phospholipase D signaling pathway bta04081   Hormone signaling bta04082   Neuroactive ligand signaling bta04114   Oocyte meiosis bta04211   Longevity regulating pathway bta04213   Longevity regulating pathway - multiple species bta04261   Adrenergic signaling in cardiomyocytes bta04270   Vascular smooth muscle contraction bta04371   Apelin signaling pathway bta04540   Gap junction bta04611   Platelet activation bta04713   Circadian entrainment bta04714   Thermogenesis bta04720   Long-term potentiation bta04723   Retrograde endocannabinoid signaling bta04724   Glutamatergic synapse bta04725   Cholinergic synapse bta04727   GABAergic synapse bta04750   Inflammatory mediator regulation of TRP channels bta04911   Insulin secretion bta04912   GnRH signaling pathway bta04913   Ovarian steroidogenesis bta04914   Progesterone-mediated oocyte maturation bta04915   Estrogen signaling pathway bta04916   Melanogenesis bta04918   Thyroid hormone synthesis bta04921   Oxytocin signaling pathway bta04923   Regulation of lipolysis in adipocytes bta04925   Aldosterone synthesis and secretion bta04926   Relaxin signaling pathway bta04927   Cortisol synthesis and secretion bta04928   Parathyroid hormone synthesis, secretion and action bta04934   Cushing syndrome bta04935   Growth hormone synthesis, secretion and action bta04970   Salivary secretion bta04971   Gastric acid secretion bta04972   Pancreatic secretion bta04976   Bile secretion bta05032   Morphine addiction bta05142   Chagas disease bta05146   Amoebiasis bta05163   Human cytomegalovirus infection bta05166   Human T-cell leukemia virus 1 infection bta05200   Pathways in cancer bta05207   Chemical carcinogenesis - receptor activation bta05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bta00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     281601 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     281601 (ADCY1)    04371 Apelin signaling pathway     281601 (ADCY1)    04020 Calcium signaling pathway     281601 (ADCY1)    04072 Phospholipase D signaling pathway     281601 (ADCY1)    04024 cAMP signaling pathway     281601 (ADCY1)    04022 cGMP-PKG signaling pathway     281601 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     281601 (ADCY1)    04081 Hormone signaling     281601 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     281601 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     281601 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     281601 (ADCY1)    04062 Chemokine signaling pathway     281601 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     281601 (ADCY1)    04923 Regulation of lipolysis in adipocytes     281601 (ADCY1)    04912 GnRH signaling pathway     281601 (ADCY1)    04913 Ovarian steroidogenesis     281601 (ADCY1)    04915 Estrogen signaling pathway     281601 (ADCY1)    04914 Progesterone-mediated oocyte maturation     281601 (ADCY1)    04921 Oxytocin signaling pathway     281601 (ADCY1)    04926 Relaxin signaling pathway     281601 (ADCY1)    04935 Growth hormone synthesis, secretion and action     281601 (ADCY1)    04918 Thyroid hormone synthesis     281601 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     281601 (ADCY1)    04916 Melanogenesis     281601 (ADCY1)    04925 Aldosterone synthesis and secretion     281601 (ADCY1)    04927 Cortisol synthesis and secretion     281601 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     281601 (ADCY1)    04270 Vascular smooth muscle contraction     281601 (ADCY1)   09154 Digestive system    04970 Salivary secretion     281601 (ADCY1)    04971 Gastric acid secretion     281601 (ADCY1)    04972 Pancreatic secretion     281601 (ADCY1)    04976 Bile secretion     281601 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     281601 (ADCY1)    04727 GABAergic synapse     281601 (ADCY1)    04725 Cholinergic synapse     281601 (ADCY1)    04720 Long-term potentiation     281601 (ADCY1)    04723 Retrograde endocannabinoid signaling     281601 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     281601 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     281601 (ADCY1)    04213 Longevity regulating pathway - multiple species     281601 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     281601 (ADCY1)    04714 Thermogenesis     281601 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     281601 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     281601 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     281601 (ADCY1)    05163 Human cytomegalovirus infection     281601 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     281601 (ADCY1)    05142 Chagas disease     281601 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     281601 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     281601 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     281601 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     281601 (ADCY1) Enzymes [BR:bta01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      281601 (ADCY1) SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  281601 NCBI-ProteinID:  NP_776654 BGD-bta:  BT10524 Ensembl:  ENSBTAG00000009520 VGNC:  25642 UniProt:  P19754 LinkDB All DBs Position 4 Genome browser AA seq 1134 aa AA seqDB search MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQ AATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLP VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYGIFVRILAERA QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA LRTASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERE RKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPV LPVPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGA GAISGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRIL FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIE MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR IQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPF GRAGLQTRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA NT seq 3405 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggcggcggaggcggaggcggcgcgggcgagtct gggggcgccgagcgggcggcggggccgggcggccggcgcgggctgcgggcgtgcgatgag gagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcag gcggcgacgctgaaggcgctggccgtgctcagcctgctggcgggcgcgctggccctggcc gagctgctgggcgcgccggggcccgcgcccggcctggctaagggctcgcaccccgtgcac tgcgtgctcttcctggcgctgctcgtggtcaccaacgtccgctcgctgcaggtgccccag ctgcagcaggtcggccagctcgcgctgctcttcagcctcaccttcgctctgctgtgctgt cccttcgcgctcggcggccccgccggtgcccacgccggggcggcagcggtgccggcgaca gccgatcagggagtctggcagctccttttggtcaccttcgtgtcctatgccctgctgccc gtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttgctggtc acggctacgttggtccccgccaagcgcccacgtctctggagaacgctgggtgccaacgct ctgctcttcctcggtgtgaacgtgtatggcatcttcgtgaggatcctggctgagcgcgcc cagaggaaggccttcctgcaggcccggaactgcattgaggaccggctgaggctggaggat gagaatgagaagcaggagcggctgctcatgagcctcctgcctcggaatgttgccatggag atgaaggaggacttcctgaagccccctgagaggattttccacaagatttacatccagcgg catgacaacgtgagcatcctctttgcagacatcgtgggcttcacaggcttggcgtcacag tgcacggcccaggagctggtgaaactcctcaatgagctcttcgggaagtttgacgagctg gccacagagaaccactgccgccgcatcaagatcctgggagattgctactactgcgtgtct ggcctcactcagcccaagactgaccacgcccactgctgtgtggagatgggcctggacatg atcgacaccatcacgtccgtggctgaggccactgaggtggacttgaacatgcgtgtgggg ctgcacaccggcagggtcctctgcggggtcctgggcctgcgtaagtggcagtatgatgtg tggtccaacgacgtgaccctggccaacgtcatggaggctgccggcctgcctgggaaggtt cacatcacaaagaccaccctggcgtgcctgaatggtgactatgaggtggagccgggacac ggacacgagaggaacagttttctgaaaactcataacattgagaccttttttattgtgccc tcgcatcggcgaaagatatttccagggctgattctctcagacataaaaccggccaagagg atgaagttcaagaccgtgtgctacctgctggtgcagctcatgcactgccggaagatgttc aaggccgagatccctttctccaacgtcatgacctgtgaggatgacgacaagcggagggca ctgagaacagcctcggaaaaactcagaaaccgctcgtctttctctacaaacgttgtccaa accacccccggcacacgtgtcaacaggtacatcggccgcctcctggaagcccgccagatg gagctggagatggcagacctgaacttcttcaccctgaagtacaagcaagctgagcgagag cgaaagtaccaccagcttcaggacgagtatttcaccagcgccgtggttctggctctcatt ctggccgccttattcggccttgtctaccttctaataatcccacagagtgtggctgtcctg ctcctgctggtgttctgcatctgcttcctggtggcctgtgtcctgtacctacacatcacc cgggtccagtgttttccagggtgcctgaccatccagatccgcaccgtcttgtgcatcttc atcgtggtcttaatctactctgtggcccaaggctgtgtggtgggctgcctgccttggtcc tggagctccagtcccaacgggtccctggtggtcctgtcttctgggggccgggacccagtg ctgcctgtcccgccctgcgagtctgcgccccatgccctgctgtgcggcctcgtgggcacc ctcccgctggccatattcctgcgggtctcctccttgccaaaaatgatcctgctcgccgtg ctcaccacctcctacatcctcgtcctggagctcagcgggtacacgaaggccatgggggcc ggtgccatctcagggcgcagcttcgagccgatcatggccatcctgctattctcgtgcacg ctggccctgcacgcccggcaggtggatgtcaagctgcggctggactacctctgggcggcc caggcagaggaggagcgggatgacatggagaaagtgaagctggacaacaagaggattctc ttcaacctcctgccagcccacgttgcccagcacttcctaatgtccaaccctcgcaacatg gacctgtattaccagtcatactcgcaggtgggggtcatgtttgcatccatccccaacttc aatgacttctacatcgagctggatggcaacaacatgggggtggaatgtctacgccttctg aatgagatcatcgctgactttgatgagctcatggacaaagacttttacaaggacctagag aagatcaagaccattgggagcacgtacatggctgctgtggggctggcgcccactgctggg accaaggctaagaagtgcatctcctcccacctcagcacgttggcagattttgccatcgag atgtttgatgtcctggatgagatcaactaccagtcttataacgactttgtgctccgtgtt ggcatcaatgttggccccgtggtggctggagtgatcggggctcgcaggccgcagtatgac atttgggggaacacggtcaatgtggccagtcggatggacagtaccggcgtccagggcagg atccaggtcacagaggaagttcaccggctgctgcggcggggttcctaccgcttcgtgtgc cgaggcaaagtcagtgtcaagggcaagggtgagatgctgacatacttcctggaaggcagg accgatggaaatggctcccaaaccaggtccctgaactcagagcggaaaatgtatcctttc ggaagagctggcctccagaccagactggctgcgggtcaccccccggtacctcctgcagcc ggcctcccagttggagctgggccaggggctctgcagggctcggggcttgccccaggcccc ccaggccaacacctgccccctggagcctctgggaaggaggcttag

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