KEGG   Bos taurus (cow): 281769
Entry
281769            CDS       T01008                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 precursor
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
bta  Bos taurus (cow)
Pathway
bta01521  EGFR tyrosine kinase inhibitor resistance
bta04010  MAPK signaling pathway
bta04014  Ras signaling pathway
bta04015  Rap1 signaling pathway
bta04020  Calcium signaling pathway
bta04144  Endocytosis
bta04151  PI3K-Akt signaling pathway
bta04550  Signaling pathways regulating pluripotency of stem cells
bta04810  Regulation of actin cytoskeleton
bta05200  Pathways in cancer
bta05206  MicroRNAs in cancer
bta05219  Bladder cancer
bta05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    281769 (FGFR3)
   04014 Ras signaling pathway
    281769 (FGFR3)
   04015 Rap1 signaling pathway
    281769 (FGFR3)
   04020 Calcium signaling pathway
    281769 (FGFR3)
   04151 PI3K-Akt signaling pathway
    281769 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    281769 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    281769 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    281769 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    281769 (FGFR3)
   05206 MicroRNAs in cancer
    281769 (FGFR3)
   05230 Central carbon metabolism in cancer
    281769 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    281769 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    281769 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bta01001]
    281769 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:bta04090]
    281769 (FGFR3)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     281769 (FGFR3)
Protein kinases [BR:bta01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   281769 (FGFR3)
CD molecules [BR:bta04090]
 Proteins
  281769 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 281769
NCBI-ProteinID: NP_776743
Ensembl: ENSBTAG00000007164
VGNC: 50180
UniProt: Q95M13
LinkDB
Position
6:complement(116766308..116781167)
AA seq 802 aa
MGAPARALAFCVAVAVMTGAALGSPGVEPRVARRAAEVPGPEPSPQERAFGSGDTVELSC
RLPAGVPTEPTVWVKDGVGLAPSDRVLVGPQRLQVLNASHEDAGAYSCRQRLSQRLLCLF
SVRVTDAPSSGDDEGGDDEAEDTAGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTP
SITWLKNGKEFRGEHRIGGIKLRQQQWSLVMESVVPSDRGNYTCVVENKFGRIQQTYTLD
VLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTP
YVTVLKTAGANTTDKELEVLSLRNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELV
EAGEAGGVFAGVLSYGLGFLLFILAVAAVTLYRLRSPPKKGLGSPAVHKVSRFPLKRQVS
LESSSSMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFG
QVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGA
CTQGGPLYVLVEYAAKGNLREYLRARRPPGTDYSFDTCRLPEEQLTFKDLVSCAYQVARG
MEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPE
ALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLY
MIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSVPFEQYSPGGQDTPSSGSSG
DDSVFAHDLLPPAPSGSGGSRT
NT seq 2409 nt   +upstreamnt  +downstreamnt
atgggcgccccggctcgcgccctcgcgttttgcgtggcagtggcggtcatgaccggcgcc
gccctcgggtccccgggcgtggagccccgcgtcgcgcggagagcggcagaggtcccgggc
cccgagcccagcccgcaggagcgggcctttggcagcggggacaccgtggagctgagctgc
cgcttgccggcgggggtgcccacagagcccaccgtctgggtgaaggacggcgtgggcctg
gcgccctcggaccgcgtcctggtggggccgcagcggctacaggtgctcaacgcctcccac
gaggacgccggagcctacagctgccgccagcgcctctcccagcggctgctgtgcctcttc
agcgtgcgcgtgacagatgctccgtcctcaggggatgacgagggtggggacgacgaggcc
gaggacacagctggggccccttactggacgcggcctgagcggatggacaagaagctgcta
gcggtgccggccgccaacacggttcgcttccgctgcccagctgctggcaaccccacgcca
tccatcacctggctgaagaacggcaaggagttccggggcgagcaccgcatcgggggaatc
aaactgcggcagcagcagtggagcctggtcatggagagcgtggtgccctcggaccgcggc
aactacacgtgcgtcgtggagaacaagttcggcagaatccagcagacctacaccctggac
gtgctggagcgctctccgcaccggcccatcctacaggccgggctgcccgctaaccagaca
gccgtgctgggcagcgatgtggagttccactgcaaggtctacagcgacgcccagccccac
atccagtggctcaagcacgtggaggtgaacggcagcaaggtggggcccgacggcacgccc
tacgtcaccgtgctcaagacggcgggcgctaacaccaccgacaaggagctagaggttcta
tccttgcgcaatgtcacctttgaggacgcgggggagtacacatgtctggcgggcaattct
atcgggttttcccatcactctgcgtggctggtggtgctgccagctgaggaggagctggtg
gaagccggtgaggctggcggtgtgttcgcgggtgtcctcagctacgggctgggcttcctc
ctcttcatcctggccgtggccgccgttacgctctaccgcctgaggagcccccctaagaag
ggcctgggctcgcccgcggtgcacaaggtctcccgcttcccgctcaagcgacaggtgtcc
ttggagtccagctcatccatgagctccaacacaccgctggtacgcattgcccggctgtca
tcgggcgagggccccaccctggccaacgtctctgagctcgagctgcccgccgaccccaag
tgggagctgtcccgggcccggctgaccctgggcaagcctcttggggagggctgcttcggc
caggtggtcatggcagaggccattggcatcgacaaggaccgagctgccaagcctgtcacg
gtggccgtgaagatgctgaaagatgacgccacggataaggacttatcggacctggtgtcc
gagatggagatgatgaagatgatcggaaaacacaagaacattatcaacctgctaggcgcc
tgcacgcagggcgggcccctgtacgtgctggtggagtacgcggccaagggcaacctgcgg
gaatacctgcgggcacggcggcccccgggcactgactactccttcgacacctgccggctg
cccgaggagcagctcaccttcaaagacctggtgtcctgcgcctaccaggtggcgcggggc
atggagtacctggcctcgcagaagtgcatccacagggacctggcggcccgcaacgtgctg
gtgactgaggacaacgtgatgaaaatcgccgacttcggcctggctcgtgacgtgcacaac
ctcgactactacaaaaagaccacaaacggccgcctgcccgtgaagtggatggcacccgag
gccttgtttgaccgcgtctacacccaccaaagtgacgtctggtccttcggggtcctgctc
tgggagatcttcacgctggggggctcgccgtaccccggcatccccgtggaggagctcttc
aagctgctgaaggaaggccaccgcatggacaagccggccaactgcacgcatgacctgtac
atgatcatgcgcgagtgctggcacgccgcgccctcgcagaggcccaccttcaagcagctg
gtggaggacctggaccgtgtgctcaccgtgacgtccaccgacgagtacctggacctgtcg
gtgcccttcgagcagtactcgccgggcggccaggacacccccagctccggctcctcgggg
gacgactccgtgttcgctcacgacctgctgcccccggccccatccggcagcggaggctcg
cggacgtga

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