Bos taurus (cow): 282089
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Entry
282089 CDS
T01008
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein precursor
KO
K13375
transforming growth factor beta-1
Organism
bta
Bos taurus (cow)
Pathway
bta04010
MAPK signaling pathway
bta04060
Cytokine-cytokine receptor interaction
bta04068
FoxO signaling pathway
bta04110
Cell cycle
bta04148
Efferocytosis
bta04218
Cellular senescence
bta04350
TGF-beta signaling pathway
bta04380
Osteoclast differentiation
bta04390
Hippo signaling pathway
bta04659
Th17 cell differentiation
bta04672
Intestinal immune network for IgA production
bta04926
Relaxin signaling pathway
bta04932
Non-alcoholic fatty liver disease
bta04933
AGE-RAGE signaling pathway in diabetic complications
bta05140
Leishmaniasis
bta05142
Chagas disease
bta05144
Malaria
bta05145
Toxoplasmosis
bta05146
Amoebiasis
bta05152
Tuberculosis
bta05161
Hepatitis B
bta05166
Human T-cell leukemia virus 1 infection
bta05200
Pathways in cancer
bta05205
Proteoglycans in cancer
bta05210
Colorectal cancer
bta05211
Renal cell carcinoma
bta05212
Pancreatic cancer
bta05220
Chronic myeloid leukemia
bta05225
Hepatocellular carcinoma
bta05226
Gastric cancer
bta05321
Inflammatory bowel disease
bta05323
Rheumatoid arthritis
bta05410
Hypertrophic cardiomyopathy
bta05414
Dilated cardiomyopathy
bta05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
282089 (TGFB1)
04350 TGF-beta signaling pathway
282089 (TGFB1)
04390 Hippo signaling pathway
282089 (TGFB1)
04068 FoxO signaling pathway
282089 (TGFB1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
282089 (TGFB1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
282089 (TGFB1)
09143 Cell growth and death
04110 Cell cycle
282089 (TGFB1)
04218 Cellular senescence
282089 (TGFB1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
282089 (TGFB1)
04672 Intestinal immune network for IgA production
282089 (TGFB1)
09152 Endocrine system
04926 Relaxin signaling pathway
282089 (TGFB1)
09158 Development and regeneration
04380 Osteoclast differentiation
282089 (TGFB1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
282089 (TGFB1)
05205 Proteoglycans in cancer
282089 (TGFB1)
09162 Cancer: specific types
05210 Colorectal cancer
282089 (TGFB1)
05212 Pancreatic cancer
282089 (TGFB1)
05225 Hepatocellular carcinoma
282089 (TGFB1)
05226 Gastric cancer
282089 (TGFB1)
05220 Chronic myeloid leukemia
282089 (TGFB1)
05211 Renal cell carcinoma
282089 (TGFB1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
282089 (TGFB1)
05161 Hepatitis B
282089 (TGFB1)
09171 Infectious disease: bacterial
05152 Tuberculosis
282089 (TGFB1)
09174 Infectious disease: parasitic
05146 Amoebiasis
282089 (TGFB1)
05144 Malaria
282089 (TGFB1)
05145 Toxoplasmosis
282089 (TGFB1)
05140 Leishmaniasis
282089 (TGFB1)
05142 Chagas disease
282089 (TGFB1)
09163 Immune disease
05323 Rheumatoid arthritis
282089 (TGFB1)
05321 Inflammatory bowel disease
282089 (TGFB1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
282089 (TGFB1)
05414 Dilated cardiomyopathy
282089 (TGFB1)
05415 Diabetic cardiomyopathy
282089 (TGFB1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
282089 (TGFB1)
04933 AGE-RAGE signaling pathway in diabetic complications
282089 (TGFB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
bta03110
]
282089 (TGFB1)
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
bta04052
]
282089 (TGFB1)
00536 Glycosaminoglycan binding proteins [BR:
bta00536
]
282089 (TGFB1)
Chaperones and folding catalysts [BR:
bta03110
]
Intramolecular chaperones
Others
282089 (TGFB1)
Cytokines and neuropeptides [BR:
bta04052
]
Cytokines
Transforming growth factors (RSTK binding)
282089 (TGFB1)
Glycosaminoglycan binding proteins [BR:
bta00536
]
Heparan sulfate / Heparin
Growth factors/receptors
282089 (TGFB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Motif
Other DBs
NCBI-GeneID:
282089
NCBI-ProteinID:
NP_001159540
Ensembl:
ENSBTAG00000020457
VGNC:
35800
UniProt:
P18341
LinkDB
All DBs
Position
18:complement(50473691..50508349)
Genome browser
AA seq
390 aa
AA seq
DB search
MPPSGLRLLPLLLPLLWLLMLTPGRPVAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGDVPPGPLPEAILALYNSTRDRVAGESAETEPEPEADYYAKEVTRVLMVEYGNKI
YDKMKSSSHSIYMFFNTSELREAVPEPVLLSRADVRLLRLKLKVEQHVELYQKYSNNSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLTRREEIEGFRLSAHCSCDSKDNTLQVDINGFS
SGRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgccgccctcggggctgcggctgctgccgctgctgctgccgctgctgtggctgctaatg
ctgacgcctggccggccggtcgccggactgtccacctgcaagaccatcgacatggagctg
gtgaagcggaagcgcatcgaggccatccgcggccagattttgtccaagcttcggctcgcc
agccccccgagccagggggatgtgccacccggcccgctgcccgaggccatactggccctt
tacaacagtacccgcgaccgggtggccggggaaagtgccgaaacggagcctgagccagag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaatacggcaacaaaatc
tatgacaaaatgaagtctagctcgcacagcatatatatgttcttcaacacgtccgagctc
cgggaagcggtgcccgaacctgtgttgctctctcgggcagacgtgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatatagcaacaattcctggcgc
tacctcagcaaccggctgctcgcccccagcgactcaccggagtggctgtcctttgacgtc
actggagttgtgcggcagtggctgacccgcagagaggaaatagagggctttcgcctcagt
gcccactgttcctgtgacagtaaagataacacgcttcaagtggacattaacgggttcagt
tccggccgccggggtgacctcgccaccattcacggcatgaaccggcccttcctgctcctc
atggccacccctctggagagggcccagcacctgcacagctcccgccaccgccgagccctg
gacaccaactactgcttcagctccacagaaaagaactgctgtgttcgtcagctctacatt
gacttccggaaggacctgggctggaagtggattcatgaacccaaggggtaccacgccaat
ttctgcctggggccctgcccttacatctggagcctggatacacagtacagcaaggtcctg
gccctgtacaaccagcacaacccgggcgcttcggcggcgccgtgctgcgtgcctcaggcg
ctggagcccctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagttgtcc
aacatgatcgtgcgctcctgcaagtgcagctga
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