Bos taurus (cow): 353120
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Entry
353120 CDS
T01008
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein homolog
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
bta
Bos taurus (cow)
Pathway
bta01524
Platinum drug resistance
bta03440
Homologous recombination
bta03460
Fanconi anemia pathway
bta04120
Ubiquitin mediated proteolysis
bta04151
PI3K-Akt signaling pathway
bta05206
MicroRNAs in cancer
bta05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
353120 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
353120 (BRCA1)
03460 Fanconi anemia pathway
353120 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
353120 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
353120 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
353120 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
353120 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
bta01009
]
353120 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
bta04121
]
353120 (BRCA1)
03036 Chromosome and associated proteins [BR:
bta03036
]
353120 (BRCA1)
03400 DNA repair and recombination proteins [BR:
bta03400
]
353120 (BRCA1)
Enzymes [BR:
bta01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
353120 (BRCA1)
Protein phosphatases and associated proteins [BR:
bta01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
353120 (BRCA1)
Ubiquitin system [BR:
bta04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
353120 (BRCA1)
Multi subunit type E3
BRCC complex
353120 (BRCA1)
Chromosome and associated proteins [BR:
bta03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
353120 (BRCA1)
DNA repair and recombination proteins [BR:
bta03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
353120 (BRCA1)
BRCA1-A complex
353120 (BRCA1)
BRCA1-B complex
353120 (BRCA1)
BRCA1-C complex
353120 (BRCA1)
BRCA complex
353120 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
353120 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
RTT107_BRCT_5
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
353120
NCBI-ProteinID:
NP_848668
BGD-bta:
BT11167
Ensembl:
ENSBTAG00000022520
VGNC:
55781
UniProt:
Q864U1
LinkDB
All DBs
Position
19:complement(43069050..43140040)
Genome browser
AA seq
1849 aa
AA seq
DB search
MDLSADHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFANSYNFSRKEDNSPEHLKE
EVSIIQSMGYRNRAKRLWQSEPENPTLQETSLTVELSNLGIVRSLRTKQQTQSQNKSVYI
ELGSDSSEDTVNKASYFSVGDHELLEITPQGAKAKTNLNPAEKAACEFSEKDITNTEHHQ
LSIKDLITTQKHATETHPEKYQGISVSDFHVEPCGTDTHASSLQHENSSLLLTENRLNVE
KAEFCNKSKQPVLVKSQQSRWAESKGTCKDRQIPSTEKKIVLNTDPLYRRKELRKQKPAC
PDSPGDSQDVPWVTLNNSIQKVNDWFSRSDEILTSDDSCDGGSESNNEVAGAVEIPNKVD
GYSGSSEKINLMASDPHGTLIHERVHSKPVESNIEDKIFGKTYRRKSSLPNFSHIAEDLI
LGAFTVEPQITQEQPLTNKLKCKRRGTSGLQPEDFIKKVDLTIVPKTPEKMTEGTDQTEQ
KCHGMNITSDGHENKTKRDYVQKEQNANPAESLEKESVFRTEAEPISISISNMELELNIH
RSKAPKNRLKRKSSTRKIPELELVVSRNPSLPNHTELPIDSSSSNEEMKKKHSSQMPVRQ
SQKLQLIGDKELTAGAKNNKTYEQINKRLASDAFPELKLTNTPGYFTNCSSKPEEFVHPS
LQREENLGTIQVSNSTKDPKDLILREGKALQIERSVESTNISLVPDTDYSTQDSISLLEA
KTPEKAKTAPNPCVSLCTATKNLKELIHRDFKDTKNNTEGFQDLLGHDINYVIQETSREM
EDSELDTQYLQNTFKASKRQTFALFSNPGNPQKECATVFAHSGSLRDQSPRDPLKCRQKE
DSQGKSESKSQHVQAICTTVHFPVADQQDRTPGDDAKCSAKEVTRVCQSSQLRGHKTELV
FANKQGVSEKPNLIPSLSPIKSSVKTICKKSPSEKFEEPVTSPEKTLGSESIIQSAVSTI
SQNNIQESTFKEVSSNSVNEVGSSTNEVGSSVNEVGSSGENIQAEPGRNREPKLRALLGL
GLTQPEVYKQSLPVSNCHHPEIKRQGENEDMPQAVKADFSPCLISDNLEQPTGSRHASQV
CSETPDNLLNDDEIKENSHFAESDIKERSAVFSESVQKGEFRGSPGPFTHTHLAQGHQRG
AGKLESEETVSSEDEELPCFQQLLFGKVTSTLSPSTGCNTVATEGLSKETEGNLESLKSG
LNDCSGQVTSAKVSQEHHLNEEARCSGSLFSSQCSAMEDLTTNTNTQDPFLMFERPSKQV
YQSESEEVLSDKELVSDDEERETGLEEDSCQEEQSVDSDLGEAVSDHVSETSLSEDGVGL
SSQSDILTTQQRDTMQDNLLKLQQEMAELEAVLERHGSQPSHSSASLTADSRGPEHLLNL
EQDTSERAILTSEKSRDYSRSQNPESLSADKFPVSLDSSTNKNKEPGMERSSASKFQLSY
NRWYMHSSRSLQDRNCPSQKEPINVADMEEQQLAKREAQDLMGSFLPRQDQEGTPYLKSG
ISLFSHEPESDPSEDRAAEPAHVHSMPPSASALKLSQFRVEESTKNPAAAHIANTTRCNL
REESMSKEKPEVISSTERSKKRLSMVASGLTPKELMLVQKFARKHHVTLTNLITEETTHV
IMKTDPEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKEGKMLDEHDFEVRGDVVNGRNHQ
GPKRARESRDKKIFKGLEICCYGPFTNMPTDQLEWMVQLCGASVVKEPSSFTPDQGTHPV
VVVQPDAWTEDAGFHVIGQMCEAPVVTREWVLDSVALYQCQELDTYLVP
NT seq
5550 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcggatcatgttgaagaagtacaaaatgtcctcaatgctatgcagaaa
atcttagagtgtccaatatgtctggagttgatcaaagagcctgtctctacaaagtgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacaa
tgtcctttgtgtaagaatgatataaccaaaagaagcctacaagaaagtacaagatttagt
caacttgttgaagagctgttgaagatcattcatgcttttgagcttgacacaggattgcag
tttgcaaacagctataacttttcgagaaaggaagataactctcctgagcatctgaaggag
gaagtttctataatccaaagtatgggctaccggaaccgggccaaaagactttggcagagt
gaacctgaaaatcctaccttgcaggaaaccagtcttactgtcgaactctctaaccttgga
attgtcagatctctgaggacaaagcagcagacacaatctcagaataagtccgtctacatt
gaattgggatctgattcttctgaagacacagttaataaggccagttatttcagtgtggga
gaccatgaattgttagaaatcacccctcaaggagccaaggccaagaccaatttgaatcct
gcagaaaaggctgcttgtgagttttctgagaaggacataacaaatactgaacatcatcaa
ctcagtattaaagatctgatcaccacccagaagcatgcaactgagacgcatccagaaaag
tatcagggtatttctgtttcagactttcacgtggagccatgtggcacagatactcatgcc
agctcattacagcatgagaacagcagtttattgctcactgaaaacagactgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcctgtcttagtaaagagccagcagagcaga
tgggctgaaagtaagggcacatgtaaggataggcagattcccagcactgagaaaaagata
gttctgaatactgatcccctgtacagaagaaaagaactgcgtaagcagaaacctgcatgc
cctgacagtcctggagattcccaagatgttccttgggtaaccctgaataatagcatacag
aaagttaatgactggttttccagaagtgatgaaatattaacttctgatgactcgtgcgat
ggggggtctgaatcaaataatgaagtagctggtgcagtggaaattccaaataaagtagat
ggatattcaggttcttcagagaaaatcaacttaatggccagtgatcctcatggtacttta
atacacgaaagagtccactccaaacccgtagagagtaatattgaagataaaatatttggg
aaaacctatcggaggaagtcaagtctccctaacttcagccacatagctgaagatctaatt
ctaggcgcatttactgtagaacctcagataacacaagagcagcccctcacaaataaacta
aaatgtaaaaggagaggtacatcaggccttcagcctgaggattttatcaagaaagtcgat
ttgacaattgttccaaagactcctgaaaagatgacggagggaactgaccaaacagagcag
aaatgtcatgggatgaatattactagtgatggtcatgagaataaaacaaaacgtgattat
gttcagaaagagcaaaacgctaacccagcagaatcattggaaaaagaatctgttttcaga
actgaggctgaacctataagcatcagtataagcaatatggaactagaattgaatatccac
cgttcaaaagcacctaagaataggctgaagagaaagtcctctaccaggaaaattcctgaa
cttgaactagtagtcagtagaaacccaagtctacctaatcatactgagctaccaattgat
agcagttctagcaatgaagagatgaagaaaaaacattctagccaaatgccagtcaggcag
agccaaaagcttcaactcattggagataaagaacttactgctggagccaagaataacaaa
acatatgaacaaataaataaaagacttgctagtgatgcttttccagaactaaagttaaca
aacacacctggttattttactaactgttctagtaaacctgaagagtttgttcatcctagc
cttcaaagagaggagaacctaggaacaattcaagtgtcgaatagtaccaaagaccccaaa
gatctgatattaagagaaggaaaagctttgcaaattgaaagatctgtagagagtaccaat
atttccttggttcctgatactgattatagcactcaggatagtatctcattactagaagct
aaaaccccagaaaaggcaaagactgcaccaaatccatgtgtgagtctgtgtacagcaacc
aaaaacctcaaggaacttatccatagggattttaaagataccaaaaacaacacagagggc
tttcaggatctactgggacatgacattaactacgtcattcaggagacaagcagagaaatg
gaagacagtgaacttgatacacagtatttgcagaatacattcaaggcttcaaagcgtcag
acatttgctctgttttccaatccaggaaatccacaaaaggaatgtgccacagtctttgcc
cactcggggtccttaagggatcaaagtccaagagaccccctcaaatgcagacaaaaagaa
gacagtcagggaaagagtgagtctaaaagccagcacgtgcaggccatttgtacaacagtg
cactttcctgtggctgatcagcaagataggacgccaggtgacgatgccaaatgtagcgca
aaagaagtaactagggtttgtcagtcatcacagttgagaggccacaaaactgaacttgtt
tttgcaaataaacaaggggtttcagaaaaaccaaatcttataccatcactttctcccatc
aagtcatctgttaaaaccatatgtaagaaaagcccatcagagaagtttgaggaacctgta
acgtcacctgaaaaaacattggggagtgagagcatcattcaaagtgcagtgagcacaatc
agccaaaataacattcaagaaagcacttttaaagaagtcagctcaaacagtgtaaatgaa
gtaggttccagtactaatgaagtaggctctagtgttaatgaagtaggttccagtggtgaa
aacattcaagcagaaccaggtagaaacagagaacctaaattaagagctttactcggatta
ggtcttacgcaacctgaagtctataagcaaagtcttcctgtaagtaactgtcaccatcct
gaaataaaaaggcaaggagaaaatgaggacatgcctcaggctgttaaggcagatttctcc
ccatgtctaatttcagataacctcgaacaacctacgggaagccgtcatgcttctcaggtt
tgttctgagacacctgacaacttgttaaatgatgatgaaataaaagaaaatagccacttt
gctgaaagtgacattaaggaaagatctgctgtttttagtgaaagtgtccaaaaaggagaa
ttcagagggagccctggccctttcacccatacacatttggctcagggtcaccaaagaggg
gctggcaaactagagtcagaagagactgtgtctagtgaggatgaagagcttccctgcttc
caacaattattgtttggtaaagtaaccagtacactgtctccatctaccggatgtaacact
gttgccactgagggtctgtctaaggaaacagaggggaacctagaatcattgaagagtggc
ttaaatgactgcagtggccaggtaacatcagccaaggtgtcccaggaacatcaccttaat
gaggaagcgagatgttctggtagcttattttcctcacagtgcagtgcaatggaagacttg
accactaatacaaacacccaggatcctttcttgatgtttgagcgtccttccaaacaagtg
tatcagtctgaaagcgaggaagttctgagtgacaaggaattggtttcagatgatgaagaa
agggaaactggcttggaagaagatagttgccaagaagagcagagtgtggattcagactta
ggtgaagcagtatccgaccatgtgagtgaaacaagcctctctgaagacggtgtggggctg
tcctctcagagcgatatcttaaccactcagcagagggataccatgcaagataacctacta
aagctccagcaggaaatggccgagctggaagctgtgttagagcggcacgggagccagcct
tcccacagctctgcttccctcacagctgattctcgtggcccagagcacctgctaaatcta
gagcaagacacatcagaaagagcaatattaacttcagagaaaagtagagactattctaga
agccagaatcctgaaagcctctctgctgacaagtttccagtatctctggatagttctacc
aataaaaataaagaaccaggaatggaaaggtcttccgcttctaaattccagttgtcgtat
aataggtggtatatgcacagctcaaggagtcttcaggacagaaactgcccatctcaaaag
gagcccattaatgttgctgacatggaagagcaacagctggctaagcgtgaggcccaagat
ttaatggggtcttttttgccgagacaagatcaagagggaaccccttatctgaaatctgga
atcagcctcttctctcatgaacccgagtctgatccctctgaagacagagccgcagagcca
gctcatgttcacagcatgccaccctcagcctctgcactgaaattatcccaatttcgagta
gaagaatctaccaagaatccagctgctgctcacattgctaatactacacgttgtaacctg
agggaagaaagtatgagcaaagagaagccagaagtgatatcttcaacagaaagaagcaag
aaaagactttctatggtggcatcaggcttgaccccaaaagaacttatgcttgtgcagaaa
tttgccagaaaacatcacgtcactttaactaatctaattactgaagagactactcatgtc
attatgaaaacagatcctgagtttgtgtgtgaacggacactgaaatatttcctgggaatt
gcaggaggaaaatgggtagttagctatttttgggtcacccagtctattaaagaaggaaag
atgctggatgagcatgattttgaagtcagaggagatgttgtcaatggaagaaaccatcaa
ggcccaaagcgagcaagagaatcccgggacaagaagatcttcaagggcctagaaatctgt
tgctatggaccttttaccaatatgcccacagatcaactagagtggatggtgcagctgtgt
ggggcttctgtggtgaaggagccctcatcattcaccccagaccagggtacccacccagtt
gtggtcgtgcagccggatgcctggacagaggatgctggcttccatgtgatcgggcagatg
tgtgaagcacccgtggtaacccgagagtgggtactggacagtgtggccctctaccagtgc
caggagctggacacctatctggtcccctag
DBGET
integrated database retrieval system
