Bos taurus (cow): 404546
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Entry
404546 CDS
T01008
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein precursor
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
bta
Bos taurus (cow)
Pathway
bta00140
Steroid hormone biosynthesis
bta00980
Metabolism of xenobiotics by cytochrome P450
bta01100
Metabolic pathways
bta05204
Chemical carcinogenesis - DNA adducts
Module
bta_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
404546 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
404546 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
404546 (HSD11B1L)
Enzymes [BR:
bta01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
404546 (HSD11B1L)
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Gene cluster
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
404546
NCBI-ProteinID:
NP_996852
BGD-bta:
BT11226
Ensembl:
ENSBTAG00000001793
VGNC:
29966
UniProt:
Q6Q7D1
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Position
7:complement(18611627..18616500)
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AA seq
287 aa
AA seq
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MKVLLLTGLGALFFAYYWDDNFDPASLHGARVLLTGVSAGIGEELAYHYARLGSHLVLTA
HTEALLQQVVGNCRKLGAPKVFYIAADMASPEVPERVVQFALDKLGGLDYLVLNHLGAAP
AGTRVRSSQSTRWLMQMNFLSYVQLTSSALPSLTDSKGSLVVVSSLLGRVPTSFSSPYSA
AKFALDSFFSSLRRELDVQEVNVAITMCVLGLRDRASAAEGVRGITRVRAAPGPKAALAV
IRGGATRASGVFYPWRFHLLCLLRSWMPHSRAWFVRQELNITTPAAA
NT seq
864 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtgctgctccttaccgggctgggagccctgttctttgcctattactgggatgac
aactttgacccagccagcctccacggagcccgtgtgctactgaccggagtcagtgccggc
ataggggaagagctggcgtatcactacgcgcgcctgggctcccacctcgtgctcactgcc
cacaccgaagctctgctgcagcaggtggtagggaactgccggaagctgggcgctcccaag
gtcttctacatcgctgcggacatggcctcccccgaggtgcccgagcgcgtggtgcagttt
gcgctggacaagctgggagggctggactacctggtgctgaaccacctcggcgccgcccca
gcaggcacgagggtccgcagctcccagtcgacacgttggctcatgcagatgaacttccta
agttacgtgcaattgacttcttcggcgctgccaagcctgactgacagcaagggctccctg
gtggtggtgtcctcattgctcggccgggtgcccacttccttctccagcccctactctgca
gccaagttcgcgctggacagcttcttcagttctctccggagggagctggacgtgcaggaa
gtgaacgtggccattaccatgtgcgttctgggtctccgagatcgtgcctcagccgccgaa
ggagtcaggggcatcacgagggtcagggccgctccagggcccaaggcagccctggccgta
atccgcggaggcgccacgcgtgcctctggggtcttctacccgtggcgcttccacctgctc
tgcctgctccgcagttggatgccacactcaagggcctggttcgtacgccaggagctcaat
ataacgacgcccgctgctgcctga
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