Bos taurus (cow): 407169
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Entry
407169 CDS
T01008
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
bta
Bos taurus (cow)
Pathway
bta00590
Arachidonic acid metabolism
bta01100
Metabolic pathways
bta01523
Antifolate resistance
bta04726
Serotonergic synapse
bta04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
407169 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
407169 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
407169 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
407169 (ALOX12)
Enzymes [BR:
bta01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
407169 (ALOX12)
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GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
407169
NCBI-ProteinID:
NP_001179265
BGD-bta:
BT10598
Ensembl:
ENSBTAG00000021933
VGNC:
25841
UniProt:
F1MFA8
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All DBs
Position
19:26787205..26800876
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AA seq
663 aa
AA seq
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MGRYRILVATGASLFAGSHNRVQLWLVGARGETELELQLRPARGQKEEFEHEVPEDLGPL
QFVKLRKHHSLVEDAWFCDRITVRGPGACEEAAFPCYRWVQGDGVLCLPEATARLAGNNA
LDVFQRHREKELKERHKIYRWATWKEGLPLTIAAGSEDDLPANMRFHEEKRLDFEWTLKA
GALEMVLKRVYTLLSSWTSLEDFDLIFWGQKSPLAEKVHQCWRDDELFGYQFLNGANPML
LRRCTSLPSRLVLPSGMEELRAQLERELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMDPSGKLLPMVIQIQPPSPISPTPPLFLPSDPPLAWLLAKTWVRNSDFQLHQLQYH
LLNTHLLAEVIAVATMRCLPGLHPVFKLLMPHIRYTMEINTRARTQLISDGGIFDKAVST
GGGGHVHLLRRALAQLTYRSLCPLDDLADRRLLGTPGALYACDALRLWEITARYVEGIVH
LFYHGDDVVKGDPELQAWCREITEVGLRQAQERGFPVSFQSQNQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAITWHLGRR
QPDMVPLGHHKEKYFSDPKAKSVLNQFQTDLENLEREITARNEQLDLPYEYLKPSHIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatcctcgtggccaccggggcctcgctcttcgccggctcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaaacggagctggagctgcagctgcgg
ccggcgcggggccagaaggaggagtttgaacacgaagttccggaggacctggggccgttg
cagttcgtgaagttgcgcaaacaccactccctggtggaggacgcgtggttctgcgaccgc
atcacggtgcggggccctggagcctgcgaggaggccgcgttcccgtgctaccgctgggtg
cagggtgacggcgtgctgtgcctgccagaggccaccgcccgcctggcaggaaacaatgca
ttggacgtgttccagagacatcgagagaaggagctgaaagaaagacataagatataccgc
tgggccacctggaaggaagggttacctctgacaatagctgcaggctctgaagacgatcta
cctgcaaatatgagattccacgaggagaagaggctggactttgagtggacactgaaggcg
ggggctctggagatggtcctcaaacgtgtttacaccctcctgagctcctggaccagtctg
gaggattttgatctcatcttctggggccagaagagccccctggctgagaaggttcaccag
tgctggcgggacgatgagttgtttggctaccagtttctcaatggcgccaaccccatgctg
ttgagacgctgcacctctctgccctcccggctggtgctgccctcggggatggaggagcta
cgggcccagctggagagagaactccagaacggttccctgtttgaggctgatttcatcctc
ctggacggaattccagccaatgtgatccgaggagagaagcagtacctggctgcccccctc
gtcatgctcaagatggaccccagtgggaagctgctacccatggtcatccagatccagcct
cccagccccatctccccgacccccccattgttcctgccctcggatcctccacttgcctgg
ctcctggcaaagacctgggtccgaaattcagatttccaactgcatcagctccaataccat
ctgctcaacacccatctgctggctgaggtcatcgctgtggccaccatgaggtgcctccca
gggctgcaccctgtcttcaagctcctgatgccacacatccgctacacgatggaaatcaac
accagggcacggactcagctcatctcagacggaggcatatttgataaagcagtgagcacc
ggtggagggggccatgtgcacttgctccgccgggccctggctcagctgacctaccgctcc
ctctgtcctcttgacgatctggctgatcgccgcctgctgggaaccccgggtgctctctac
gcctgtgatgctttacggctctgggaaatcactgcccggtatgtggaggggattgtccac
ctcttctaccatggggacgacgttgtaaaaggggaccctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgcgccaggcccaggagcgaggcttccctgtctccttccag
tcccagaatcaactctgccatttccttaccatgtgtgtcttcacgtgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccttgcaca
atgcggatgcccccacccaccactaaggaagatgtgacaatggccacagtgatgggctca
ctacctgatgtccgacaagcctgtcttcaaatggccatcacatggcatctgggtcgccgt
cagccagacatggtgcctctggggcatcacaaagaaaagtatttctcagaccccaaggcc
aaatctgtactaaaccaattccaaacagatctggaaaacttggaaagggaaattacagcc
cgcaatgagcaacttgacctgccctatgaatacctaaagcccagccacatagagaacagc
gtcactatttga
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