Bos taurus (cow): 408015
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Entry
408015 CDS
T01008
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
bta
Bos taurus (cow)
Pathway
bta04010
MAPK signaling pathway
bta04020
Calcium signaling pathway
bta04022
cGMP-PKG signaling pathway
bta04024
cAMP signaling pathway
bta04260
Cardiac muscle contraction
bta04261
Adrenergic signaling in cardiomyocytes
bta04270
Vascular smooth muscle contraction
bta04713
Circadian entrainment
bta04720
Long-term potentiation
bta04723
Retrograde endocannabinoid signaling
bta04724
Glutamatergic synapse
bta04725
Cholinergic synapse
bta04726
Serotonergic synapse
bta04727
GABAergic synapse
bta04728
Dopaminergic synapse
bta04742
Taste transduction
bta04911
Insulin secretion
bta04912
GnRH signaling pathway
bta04921
Oxytocin signaling pathway
bta04924
Renin secretion
bta04925
Aldosterone synthesis and secretion
bta04927
Cortisol synthesis and secretion
bta04929
GnRH secretion
bta04930
Type II diabetes mellitus
bta04934
Cushing syndrome
bta04935
Growth hormone synthesis, secretion and action
bta05010
Alzheimer disease
bta05020
Prion disease
bta05022
Pathways of neurodegeneration - multiple diseases
bta05031
Amphetamine addiction
bta05207
Chemical carcinogenesis - receptor activation
bta05410
Hypertrophic cardiomyopathy
bta05412
Arrhythmogenic right ventricular cardiomyopathy
bta05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
408015 (CACNA1C)
04020 Calcium signaling pathway
408015 (CACNA1C)
04024 cAMP signaling pathway
408015 (CACNA1C)
04022 cGMP-PKG signaling pathway
408015 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
408015 (CACNA1C)
04929 GnRH secretion
408015 (CACNA1C)
04912 GnRH signaling pathway
408015 (CACNA1C)
04921 Oxytocin signaling pathway
408015 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
408015 (CACNA1C)
04924 Renin secretion
408015 (CACNA1C)
04925 Aldosterone synthesis and secretion
408015 (CACNA1C)
04927 Cortisol synthesis and secretion
408015 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
408015 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
408015 (CACNA1C)
04270 Vascular smooth muscle contraction
408015 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
408015 (CACNA1C)
04727 GABAergic synapse
408015 (CACNA1C)
04725 Cholinergic synapse
408015 (CACNA1C)
04728 Dopaminergic synapse
408015 (CACNA1C)
04726 Serotonergic synapse
408015 (CACNA1C)
04720 Long-term potentiation
408015 (CACNA1C)
04723 Retrograde endocannabinoid signaling
408015 (CACNA1C)
09157 Sensory system
04742 Taste transduction
408015 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
408015 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
408015 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
408015 (CACNA1C)
05020 Prion disease
408015 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
408015 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
408015 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
408015 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
408015 (CACNA1C)
05414 Dilated cardiomyopathy
408015 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
408015 (CACNA1C)
04934 Cushing syndrome
408015 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
bta04040
]
408015 (CACNA1C)
Ion channels [BR:
bta04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
408015 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Motif
Other DBs
NCBI-GeneID:
408015
NCBI-ProteinID:
XP_024848514
Ensembl:
ENSBTAG00000010660
VGNC:
59325
LinkDB
All DBs
Position
5:108334919..108794045
Genome browser
AA seq
2167 aa
AA seq
DB search
MLRAFFPHSTPGYQPLPRRPAKTQAGSRGTLVHEAQLSCSYVSPGGPSYGSPRPAHANMN
ANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKK
QGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDD
SNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAI
LEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHI
ALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTV
CKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIII
GSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN
EDEGLDEEKPRNMSMPTSETESVNTENVAGGDIEGESCGARLAHRISKSKFSRYWRRWNR
FCRRKCRAAVKSSIFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEM
LLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT
RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDN
FPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAI
AVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVVEKPAVEETKEEKIELKSITA
DGESPPATKINMDDLQPNENEDKSSYPNQETTGEEDEEEPEMPVGPRPRPLSELHLKEKA
VPMPEASAFFIFSPSNRFRLQCHRIVNDSIFTNLILFFILLSSISLAAEDPVQHTSFRNH
ILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAI
NVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLF
KGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTV
STFEGWPELLYRSIDSHTEDKGPIYNYRVEISVFFIIYIIIIAFFMMNIFVGFVIVTFQE
QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILL
NTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMVLKLIAFKPKHYFCDAWNTFDALIV
VGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLW
TFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFR
CATGEAWQDIMLACMPGKKCAPESEPGNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF
VAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFG
KLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKK
IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL
QAGLRTLHDLGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVGYYP
SDGRGAFPQTFTTQRPLHISKAGNSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN
NTALGRCPRPALHSGAVSTLEAHGPPLSPAIRVQEAAWRHSSQRCPSRDSPIAMLCQEEA
SGDETCAVHVDENAEHSSEPSLVSTEMLSYQDDENRQLTPPEEDRRDIRLSPKRGFLRSA
SLGRRASFHLECLKRQKNPGGDVSQNTVLPLHLVHHQALAVAGLSPLLQRSHPPGTLPPP
RLTPPATPGPAWPPRPVPTLRLEGAESSDKLTSSFPSIHCDPHIGEPTPCGVVGTPRRAR
PVSLTVPSPAGPQGRPFHGSASSLVEAVLISEGLGQFAQDPRFLEATTQELADACDMTIE
EMESAADDILSGGAGQSPNGTLLPCANCRDPGPDRAGGVEDAAWAPSAEPRQGAEEPRDS
RAFASGL
NT seq
6504 nt
NT seq
+upstream
nt +downstream
nt
atgctgcgagccttctttccccactccacgcccgggtaccagccgctgccccgccgcccc
gccaaaacccaggcgggctccaggggtacgctggtgcacgaggctcagctgagctgctcc
tatgtctctcctggaggtcccagctatgggagcccgcgcccggctcacgccaacatgaac
gccaacgcggccgcggggctggcacctgagcacatccccacaccgggggccgccctgtcc
tggcaggccgccatcgacgcggcccggcaggccaagctgatgggcagtgctggcaacgca
accatctccacggtcagctccacgcagcggaaacggcagcagtatgggaagcccaagaag
cagggcagcacgacagccacccgcccgccccgcgccctgctctgcctgaccctaaagaac
cccatccggagggcctgcatcagcatcgtcgagtggaagccatttgaaatcattatttta
ctgactatttttgccaattgtgtggccttagcgatctatattcccttcccagaggacgac
tccaacgccacgaattccaacctggagcgggtggagtatctcttcctcatcatttttact
gtggaagcatttttaaaagtcatagcctacggactcctctttcaccccaacgcttacctc
cgcaatggctggaacttactagactttatcatcgtggttgtcgggcttttcagcgcgatc
ttagagcaagcgaccaaagccgatggggccaacgccctgggagggaagggtgctggattc
gacgtaaaggcgctgagggcgttccgtgtgctacggcccctgcggttggtgtccggggtc
ccgagtctccaggtggtcttgaattccatcatcaaggccatggtgcccctgctgcacatc
gccctgctcgtgctgttcgtcatcatcatctatgccatcatcggcctggagctcttcatg
ggcaagatgcataagacctgctacaaccaggagggcattgcagatgtcccagcagaagac
gacccctcgccctgtgccctggagacaggccacgggcggcagtgccagaatggcacggtg
tgcaaaccaggctgggatggacccaagcacggcatcaccaatttcgacaacttcgccttc
gccatgctgactgtgttccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaatgatgccgtgggaagggactggccctggatctattttgtcacattaatcatcata
ggttcattctttgttcttaacttggttctcggtgtccttagcggagagttctccaaagag
cgagagaaggccaaggcccggggagacttccagaagctgcgagagaagcagcagctggag
gaggacctgaagggctacctggactggatcacgcaggccgaggacatcgaccccgagaat
gaggacgagggcctggacgaggagaaaccccgaaacatgagcatgcccaccagtgagacc
gagtctgtcaacaccgaaaacgtggctggaggggacatcgagggagagagctgcggggcc
aggctggcccaccggatctccaagtcaaagttcagccgctactggcgccggtggaatcgg
ttctgcaggaggaagtgccgcgcggccgtgaagtccagcatcttctactggctggtcatc
ttcctggttttcctcaacacactcaccatcgcctccgagcactacaaccagccccactgg
ctcacggaagtccaagacacggccaacaaggcgctgctggccctgttcacggcggagatg
ctgctcaagatgtacagcctgggcctgcaggcctacttcgtgtcgctcttcaaccgcttc
gactgcttcatcgtgtgcgggggcatcctggagaccatcctggtggagaccaagatcatg
tcgccgttgggcatctccgtgctgcgttgcgtgcgcctccttcggatatttaagatcaca
aggtactggaactccctgagcaacctggtggcatccctgctgaactcagtgcgctccatt
gcctcgctgctgctgctgctcttcctcttcatcatcatcttctccctcctggggatgcag
ctctttggggggaagttcaactttgatgagatgcagacccggaggagcacctttgacaac
ttcccgcagtccctcctcaccgtgtttcagatcctgaccggggaggactggaattcggtg
atgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgtatt
tacttcatcatcctcttcatctgtggaaattatatcctactgaacgtgttcttggccatt
gctgtggacaacctggctgacgcggagagcctcacatctgcccagaaggaggaggaagag
gagaaggagaggaagaagctagccaggaccgccagcccagagaagaagcaagaggtggta
gagaagccggccgtggaggagaccaaggaggagaaaatcgagctgaaatccatcacggca
gatggagagtccccacccgccaccaagatcaacatggatgacctccagcccaacgagaat
gaggacaagagctcctaccccaaccaggaaaccacaggagaagaggacgaggaggagccc
gagatgcccgtgggcccccgcccgcgccccctctctgagctgcacctgaaggagaaggca
gtgcccatgccggaagccagcgccttcttcatcttcagccccagcaacaggttccgcctc
cagtgccatcgcatcgtcaatgactccatcttcaccaacctgatcctcttcttcatcctg
ctcagcagcatctccctggccgccgaggaccccgtgcagcacacctccttcaggaaccac
attctgttttattttgacattgttttcactaccattttcaccattgagattgccctgaag
atgacggcctacggggccttcctgcacaagggctccttctgccgcaactacttcaacatc
ctggacctgctggtggtcagtgtgtccctcatctccttcggcatccagtccagtgccatc
aacgtggtgaagatcctgcgagtcctgagggtgctccggccactgagggccatcaacagg
gccaaggggctgaagcacgtcgtgcagtgcgtgttcgtggccatccgcaccatcgggaac
attgtgatcgtcaccacgctgctccagttcatgttcgcctgcattggggtccagctcttc
aagggaaagctctacacctgttcggacagttccaaacagacagaggctgaatgcaagggg
aactacataacatacaaggatggggaggtggaccaccccatcatccagccccgcagctgg
gagaacagcaagtttgactttgacaatgtcctggcagccatgatggccctgttcaccgtc
tccaccttcgagggatggccagagttgctgtaccgctccatcgactctcacacggaggac
aagggtcccatatacaactaccgcgtggagatctccgtcttcttcatcatctacatcatc
atcattgccttcttcatgatgaacatcttcgtgggtttcgtcatcgtcaccttccaggag
cagggggagcaggaatacaagaactgcgagctggacaagaaccagcggcagtgtgtggag
tatgccctcaaggcccggcccctgcggaggtacatcccgaaaaaccagcaccagtacaag
gtgtggtacgtggtcaactccacctacttcgagtacctgatgttcgttctcattctgctc
aacaccatctgcctggccatgcagcactacggtcagagctgtctgttcaaaatcgccatg
aacatcctcaacatgctcttcaccggcctcttcacagtggagatggtcctgaagctcatc
gccttcaagcccaagcactatttctgtgatgcatggaacacatttgacgccttgattgtt
gtgggtagcattgttgatatagccatcaccgaggtaaacccagctgaacatacccaatgc
tctccctttatgaacgcggaagagaactctcgcatctccatcaccttcttccgcctcttc
cgggtcatgcgtctggtcaagctgctgagccgcggggagggcatccggacactgctgtgg
accttcatcaagtccttccaggccctaccctatgtggccctcctgatcgtgatgctgttt
ttcatctacgccgtgatcgggatgcaggtgtttggcaaaattgccctgaatgacacgaca
gagatcaacaggaacaacaacttccagaccttcccccaggccgtgctgctcctcttcagg
tgcgccactggggaggcctggcaggacatcatgctggcctgcatgcctggcaagaagtgc
gcccccgagtcagagccgggcaacagcacagagggggagacgccctgtggcagcagcttc
gccgtcttctacttcatcagcttctacatgctctgcgccttcctgatcatcaacctcttc
gtagccgtcatcatggacaactttgactacctgacgagggactggtccatcctgggtccc
caccacctggacgaatttaagagaatttgggcagagtatgaccctgaagccaagggacgc
atcaaacacctggatgtggtgaccctgctccgacggattcagccccccctgggttttggg
aagctgtgccctcaccgcgtggcttgcaaacgcctggtctccatgaacatgcccctgaac
agcgacgggactgtcatgttcaatgccacgctgtttgccctggtccgtacagctctgagg
atcaagacggaagggaacctggaacaggccaatgaggagctgcgggccatcatcaagaag
atctggaaacggaccagcatgaagctgctggaccaagtggtgccgcccgcaggagatgac
gaggtcacggtgggcaagttttacgctactttcctgatccaggagtatttccggaagttc
aagaagcgcaaagagcaaggcctggtgggcaagccctcccagaggaacgccctgtccctg
caggctggcctgcgcaccctgcacgatctggggcccgagatccgccgggccatctctggg
gacctgaccgccgaggaggagctggacaaggccatgaaggaggctgtgtctgcagcctca
gaagatgacatcttcaggagggccggcggcctgttcggcaaccacgtgggctactacccg
agcgacggccggggcgccttcccccagaccttcaccacccagcgccccctgcacatcagc
aaggcaggcaacagccagggggacaccgagtccccctcccacgagaaactggtggactcc
accttcacccccagcagctactcatccacgggctccaacgccaacatcaacaacgccaac
aacaccgccctgggccgctgcccccgccccgcgctccactccggtgctgtcagcaccttg
gaggcccacgggccccccttgtcccctgccatccgggtgcaggaggccgcgtggaggcac
agctcccagaggtgcccctcccgggacagcccgatagccatgctgtgtcaggaagaggcc
tctggggacgagacctgtgccgtgcacgtggacgagaacgcagagcacagcagcgagccc
agcttggtctccacggagatgctctcctaccaggatgacgagaatcggcagctgactccc
cccgaggaggacaggagggacatccgtctgtccccaaagaggggcttcctgcgctccgcc
tccctaggtcgaagggcctccttccaccttgaatgtctgaagcgacagaagaatcctggg
ggagacgtctctcagaacacagtcctgcctttgcacctggttcaccatcaggcgctggca
gtggcgggtctgagccccctcctgcagagaagccatccccctgggaccctccccccacca
cgcctcacaccccccgccacacctggcccagcctggcctccgcggcctgtgcccaccctg
cggctggaaggggccgagtccagcgacaagctcaccagcagcttcccatccatccactgc
gacccccacatcggggagcccacgccctgcggggttgtcggcaccccccggagggcccgg
cccgtgtcactcactgtgcccagcccggcagggccccagggccgtccgttccatggcagt
gccagcagcctggtggaggcggtcttgatctcggaaggattggggcagtttgctcaggac
cccaggttcctcgaggccaccacgcaggagctggccgatgcctgcgacatgaccattgag
gagatggagagcgcggctgacgacatcctcagcgggggcgccgggcagagccccaacggc
accctgctcccgtgtgcaaactgcagggacccggggccggaccgagcggggggtgtggag
gacgcagcctgggcgcccagcgccgagccccgccagggcgcagaggagccccgggacagc
agggccttcgccagcggcctgtag
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integrated database retrieval system
