Bos taurus (cow): 503684
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Entry
503684 CDS
T01008
Symbol
HMGCS2
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase, mitochondrial precursor
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
bta
Bos taurus (cow)
Pathway
bta00280
Valine, leucine and isoleucine degradation
bta00650
Butanoate metabolism
bta00900
Terpenoid backbone biosynthesis
bta01100
Metabolic pathways
bta03320
PPAR signaling pathway
Module
bta_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
503684 (HMGCS2)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
503684 (HMGCS2)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
503684 (HMGCS2)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
503684 (HMGCS2)
Enzymes [BR:
bta01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
503684 (HMGCS2)
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GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
ACP_syn_III
DUF627
Motif
Other DBs
NCBI-GeneID:
503684
NCBI-ProteinID:
NP_001039348
BGD-bta:
BT17324
Ensembl:
ENSBTAG00000003898
VGNC:
29881
UniProt:
Q2KIE6
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Position
3:23536604..23560576
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AA seq
508 aa
AA seq
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MQRLLTPVRQVLQVKRVMQEASLLPARLLPAAHPSFSTVPAVPLAKTDTWPKDVGILAME
VYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQQLMERTQLP
WDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWM
ESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYD
FYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEKQWKQAGIDRPFTLDDVQYMIF
HTPFCKLVQKSLARLMFNDFLLASGDTQTGIYKGLEAFRGLKLEDTYTNKDVDKAFLKAS
LNMFNKKTKNSLYLSTYNGNMYTSSLYGCLASLLAHHSAQDLAGSRIGAFSYGSGLAASF
FSFRVSQDASPGSPLEKLVSSTSDLQKRLASRKRVSPEEFTEIMNQREQYYHKMNFSPPG
DKNSLFPGTWYLERVDELYRRKYARRPV
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgcagcggctgttgactccagtgaggcaggtgttgcaagtgaagagagtgatgcaagaa
gcttccctcctgcctgcccgccttctcccagcagcccaccccagtttttctacagttccg
gctgtccccttggccaaaacagatacttggccaaaggatgtgggtattcttgccatggag
gtctactttccagcccaatatgtggaccaaacagagctggagaagtttaacaaagtggag
gcagggaggtacaccgtgggcttgggccagacccagatgggcttctgctcagtccaggag
gatgtcaactccctgtgcctgacggtggtgcaacagctgatggagcgcacgcagctcccc
tgggactctgtgggccgcctggaagtgggcactgagaccatcatcgataagtccaaggct
gtcaaaacagtgcttatggagctcttccaggattcaggcaacactgacattgagggcata
gataccaccaatgcctgctacggtggcactgcctccctcttcaatgctgccaactggatg
gaatccagctcctgggatggtcgctatgcactggtggtctgtggggacatcgcagtctac
cccagtggtaacgctcgccccacaggcggggctggagctgtggcaatgctggttgggcct
gaggcccctctggtcctcgagagagggcttagaggaacccacatggagaatgtgtacgac
ttctacaaaccagatgtgacttcagagtacccactggtggatgggaagctctccatccag
tgctacttacgggccctggacaaatgctatgcattctaccgtcaaaagatcgagaaacag
tggaagcaagctggcatcgatcggcctttcactctcgatgatgtgcagtatatgattttt
cacacgcctttctgcaagttagtccagaaatccctggcccgcctgatgttcaatgacttc
ctgttggccagtggtgacacacagactggcatctacaagggcttggaggccttcagggga
ctaaagctggaagacacctacaccaataaggatgtagataaagcatttctaaaagcctct
ctgaacatgttcaataagaaaaccaagaactccctctacctctccacgtacaacgggaat
atgtacacctcatccctatatggatgcctggcctcacttctggcccatcactctgcccaa
gacttggctggctccaggatcggtgccttctcttatggctctggtttggcagcaagtttc
ttttctttccgggtgtcccaggatgcttctccaggctccccactggagaagctggtatcc
agtacatcagacctgcagaaacgtcttgcctcccggaagcgtgtgtctcctgaggagttc
acagaaataatgaaccaaagagaacaatactaccacaagatgaatttctcaccacctggt
gataagaacagccttttcccaggcacttggtacctggagcgagtggatgagctgtatcgc
aggaagtacgcccggcgtcccgtttaa
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