Entry |
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Symbol |
HMGCS
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Name |
hydroxymethylglutaryl-CoA synthase [EC: 2.3.3.10]
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Pathway |
map00280 | Valine, leucine and isoleucine degradation |
map00900 | Terpenoid backbone biosynthesis |
map01110 | Biosynthesis of secondary metabolites |
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Module |
M00088 | Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone |
M00095 | C5 isoprenoid biosynthesis, mevalonate pathway |
M00849 | C5 isoprenoid biosynthesis, mevalonate pathway, archaea |
|
Reaction |
R01978 | acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) |
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Disease |
H01123 | HMG-CoA synthase deficiency |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase
Enzymes [BR:ko01000]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Montamat F, Guilloton M, Karst F, Delrot S |
Title |
Isolation and characterization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl-coenzyme A synthase. |
Journal |
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Sequence |
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LinkDB |
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