KEGG   Bos taurus (cow): 504261
Entry
504261            CDS       T01008                                 
Symbol
CAD
Name
(RefSeq) CAD protein
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
bta  Bos taurus (cow)
Pathway
bta00220  Arginine biosynthesis
bta00240  Pyrimidine metabolism
bta00250  Alanine, aspartate and glutamate metabolism
bta01100  Metabolic pathways
bta01240  Biosynthesis of cofactors
Module
bta_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    504261 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    504261 (CAD)
   00220 Arginine biosynthesis
    504261 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:bta01002]
    504261 (CAD)
Enzymes [BR:bta01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     504261 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     504261 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     504261 (CAD)
Peptidases and inhibitors [BR:bta01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   504261 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   504261 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 ATP-grasp_3 Peptidase_C26 GARS_A
Other DBs
NCBI-GeneID: 504261
NCBI-ProteinID: NP_001178322
Ensembl: ENSBTAG00000017894
VGNC: 59209
UniProt: F1MVC0
LinkDB
Position
11:complement(72393099..72414665)
AA seq 2225 aa
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPPDEVDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSASCTLHEWLQQHGIPGLQGVD
TRELTKKLREQGSLLGKLVQDGTEPSTLPFLDPNARPLVPEVSTKVPQVFNAGGTPRILA
LDCGLKYNQVRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPNLVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
TDSLPASWLPLFTNANDHSNEGIVHESLPFFSVQFHPEHQAGPSDMELLFDIFLETVKET
AAGNPGGQTVRERLAERLCLLGIPTPGSGLTAPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFASRMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAYALGGLGSGFASNKEELSALVAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM
KRIIAHTQLLEQHRGQPLPPDLLHQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMREEVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGESPPQRSI
LEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKAHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPITDAPALALAQKLAEAGARCDYALFLGASSENAGTLGTVAGSAAGLKLYLN
ETFSKLRLDSVAQWMEHFETWPSHLPIVAHAERQSVAAVLMVAQLAQRSVHICHVARKEE
ILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPKLGSREDVEALWENMAII
DCFASDHAPHTVEEKCGPRPPPGFPGLETMLPLLLTAVSEGRLSLDDVLQRLHHNPRRIF
HLPPQEDTYVEVDLEHEWTVPSHMPFSKAHWTPFEGQKVKGTIRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQLTPSAPAASELTTTPERPRRSGPALPDGRFHLPPRIHRASD
PGLPAEEPKEKTSRKAAEPELMGTLDGICYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS
LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPPDVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq 6678 nt   +upstreamnt  +downstreamnt
atggccgccctggtgttggaggacgggtcggtcctgcggggccagccctttggggccgct
gtgtcgactgccggggaagtggtgtttcaaaccggtatggtcggctaccccgaggccctg
actgacccttcctacaaagcacagatcttagtgctgacataccctctgatcggtaactac
ggaatccccccggatgaagtggatgagttcgggctcagcaagtggtttgaatcctcgggg
atccacgtggcaggactggtggtgggagagtgctgtcccacacccagccactggagtgcc
agctgcactctgcacgagtggctgcaacaacatggcatacccggcctgcaaggagtggac
actcgggagctgactaagaagctgcgagagcaagggtctctgctgggcaagttggtccag
gatgggacagaaccttcaaccctgcccttcttggaccccaatgcccgccccctggtgcca
gaggtctccactaaggttccccaggtattcaacgcagggggtacccctcggatccttgct
ttggactgtggcctcaagtataatcaggtccgatgcttgtgccagcgtggggcagaggtc
actgtggtaccctgggaccacgcgttagacagtcaagagtatgagggtctcttcctgagt
aatggccctggtgaccctgcctcctatcccaacttggtatccacactgagccgtgtttta
tctgaaccaaacccccgacctgtcttcgggatctgtctgggacaccagcttttggcctta
gccattggggccaagacttacaagatgagatatgggaaccgaggccataaccagccatgc
ttgctggtgggctctgggcgctgctttctaacatcccagaaccatggatttgctgtggaa
acagactcgctgccagcaagctggcttcctctcttcaccaatgccaatgatcactccaac
gaaggcatcgtacatgagagcctgcccttcttcagtgtccagtttcacccagagcatcaa
gctggcccttcagatatggaacttctttttgacatttttctggaaactgtgaaagaaact
gcagctggaaaccctgggggccagacagttcgagagcggctggctgagcgcctctgtctc
cttgggattcccaccccaggctctgggcttacagcaccacgaaaggttctgattctgggc
tcagggggcctctccatcggccaggccggcgagtttgactactcaggctctcaggcgatc
aaggccctgaaggaggaaaacattcagacattgctgatcaaccctaacatcgctaccgtg
cagacttcacaggggctggcggacaaggtctatttcctccccataacacctcactacgta
acccaggtgatacgtaatgagcgcccagatggtgtgttactgacttttgggggccaaaca
gctctgaactgtggtgtggagctgaccaaggctggggtgcttgctcggtacggagtccgg
gtcctgggcacacccgtggagaccattgagttgactgaagatcggcgtgccttcgcctcc
aggatggcagagatcggagagcatgtggcccccagcgaggcagcgaattctcttgagcag
gcccaggcagctgctgagagactgggataccctgtgctggtgcgcgcagcctacgccttg
ggtggcctgggctctggctttgcctctaacaaagaggagttgtctgctctcgtggcccca
gcttttgcccataccagccaagtgctggtagataagtccctgaaaggatggaaggagatt
gagtatgaggtggtgagagatgcctatggcaactgtgtcacggtgtgtaacatggagaac
ctagacccgctgggcatccacaccggggagtccatcgtggtggctccaagccagacgcta
aatgacagggagtaccagctgctgaggcagacggccatcaaggtgactcagcacctcgga
atcgtcggggagtgcaacgtgcagtatgccctgaaccctgagtctgagcagtactacatc
attgaagtgaatgccaggctctctcgcagctctgccctagccagtaaggccacaggctac
ccactggcctatgtggcagccaagctggctttgggcatccctctgcctgaactcaggaac
tctgtgacagggggaacggcagcctttgaacccagtctggattactgtgtggtgaagatt
cctcgctgggacctcagcaagttcctccgcgtcagcacaaagattgggagctgcatgaag
agcgtgggtgaagtcatgggcattgggcgttcttttgaggaggccttccagaaggctctg
cgcatggtggatgagaactgcgtgggctttgatcacacggtcaagcccgtcagtgatatg
gagttagagactccaacagacaagcgcatcttcgtggtggcagcagccctatgggctggc
tactcagtggatcgcctgtatgaactcactcgcatcgaccgctggttcctgcaccggatg
aagcggatcatagcacacacccagctgctagagcaacaccgtggacaacctttgccccca
gacctgcttcatcaggccaagcgccttggcttctcagacaagcagattgccctcgcggtc
ctcagcacagagctggctgttcgcaagctgcgtcaggaactagggatctgcccagcagtg
aagcagattgacacggttgcagctgagtggccggcccagacaaattacttgtacctgaca
tactggggcaccacccatgacctcacctttcgaacaccccatgtcctagtccttggctct
ggcgtctaccgtatcggctccagcgtcgagtttgactggtgtgccgtgggctgtatccag
cagctgcgaaagatggggtataagaccatcatggtgaactacaacccagagacagtcagc
accgactacgacatgtgtgaccgactctacttcgatgaaatctcttttgaggtggtgatg
gacatctatgagctggaaaaccctgaaggtgtgatcttgtccatgggtgggcagctgccc
aacaacatggccatggctttgcatcggcaacagtgtcgggttctgggcacctccccagaa
gccattgactcagctgagaaccgttttaagttctcccggctcctggacaccattggtatc
agccagcctcagtggagggagctcagtgacctagagtctgctcgccagttctgccagacc
gtggggtacccctgtgtcgtgcgcccctcctatgtgctgagtggtgctgctatgaacgtg
gcctacaccgatggggacttggagcgcttcttgagcagtgcagcagctgtctccaaggag
caccccgtggtcatctccaagttcatccaggaggccaaggagattgacgtggatgctgtg
gcttgtgatggtgtggtggcagctatcgccatctccgaacacgtagagaatgcaggtgtg
cattcaggtgatgccacactggtgaccccaccgcaggacatcactgccaaaaccctggag
cggatcaaagccattgtgcatgccgtgggccaggagctgcaggtcacaggacccttcaat
ctgcagctcattgccaaggacgaccagctgaaagtcattgaatgcaacgtgcgtgtgtct
cgctccttccccttcgtctccaagacactaggtgtggacctagtagccttggcgacacgg
gtcatcatgagggaagaagtggagcctgtgggactcatgactggctctggagttgtgggg
gtgaaggtgccccagttctcgttctcccgcctggcgggggctgacgtggtgctgggtgtg
gagatgaccagtactggggaagtagctggctttggggagagccgctgcgaagcctacctc
aaggccatgctcagtactggttttaagatccccaagaagaacatcttgctgaccattggc
agctataagaacaaaagtgagttgctcccaactgtgaggctgctggagagcctgggctac
agcctatacgccagtctgggcaccgctgacttctacacagagcatggtgtcaaggtgacg
gctgtggactggcattttgaagaggcagtggatggagagtccccaccacagcgaagcatt
ttggagcagcttgctgagaaaaactttgaactcgtaattaacctgtccatgcgtggggcc
gggggccggcgtctttcttccttcgtcaccaagggctaccggacacggcgcctggccgct
gacttctccgtacccctcatcattgatatcaagtgcaccaaactgtttgtggaggcgctg
ggacagattgggccagcccctcctctgaaggcgcatgttgactgcatgacctcccagaag
ctcgtgcggctgcctggattgatcgacgtccatgtgcacctgcgggaaccaggggggaca
cacaaggaggactttgcctcgggcacagctgctgccctggccgggggcgtcaccatggtg
tgcgctatgcccaatacccggccccccatcactgatgcccctgccctggccctggcgcag
aagctggcagaggccggcgcccgctgtgactatgccttattcctcggagcctcgtcggaa
aatgcagggaccctgggcactgtggctgggtctgctgcggggctgaagctctacctcaac
gagaccttctctaaactgcggctggacagtgtggcccagtggatggagcacttcgagaca
tggccatcccacctccccatcgtggcccacgccgagcggcagagtgtcgcagccgtcctc
atggtggcccagctggcccagcgctcggtgcacatctgtcatgtggcacggaaggaggag
atcctgctgattaaagcggctaaggcgcgggggctgccggtgacctgtgaggtggcaccc
caccatctgttcctgagccatgatgacctggagcgtctggggcccgggaagggggaggtt
cggcccaaacttggctcccgggaggacgtggaagccctatgggagaacatggccatcatc
gactgttttgcctccgaccacgccccccacaccgtggaggagaagtgtgggccccggcct
ccccccggcttcccagggctggagaccatgctgcccctgctgctgacggcagtgagcgag
ggccggctcagcctggacgacgtgctgcagcgactgcaccacaaccctcggcgcatcttc
cacctgccccctcaggaggacacctatgtggaggtggatctggagcacgaatggacagtc
cccagccacatgcccttctccaaggcccactggacaccctttgaagggcagaaggtgaag
ggcaccatccgccgtgtggtcctgcgtggggaggtggcctatattgacgggcaggtgctg
gtgccacccggctatggacaggacgtccgcaagtggccccagggtgctgttccacagctc
acgccctcggccccggctgccagtgagctaaccacgaccccggagaggccccgccggagc
ggcccagcactccctgatggccgcttccacctgcctccccggatccaccgagcctctgac
ccaggtttgccagctgaggagccaaaggagaagacctcccgcaaggcagctgagccagag
ctgatgggaacccttgatggcatctgctaccctccaccaccagtacctagacaggcgtca
ccccagaacctggggacccctggcctgctgcacccccagacctcacccctgctgcactca
ctagtgggccaacatatcctgtccgtccagcagttcaccaaggatcagatgtctcacctg
ttcaacgtggcacacacgctgcgcatgatggtacagaaggagcggagcctcgacatcctc
aaggggaaggtgatggcctccatgttctacgaggtgagcacacggaccagcagctccttt
gcagcagccatggcccggctcgggggcgctgtgctcagcttctccgaagccacgtcctcc
gtccagaagggcgagtccctggctgactcggtgcagaccatgagctgctacgctgatgtc
gttgtgctgcggcacccccagcccggggcagtggagctggcagccaagcactgccggagg
ccagtgatcaacgcaggggacggggttggagagcaccctacccaggccttgctggacatc
ttcaccatccgggaggagcttgggacggtcaatggcatgacgatcacgatggtgggcgac
ctgaagcatggccgcacggtgcattcgctggcctgcctgctcacccagtaccgtgtcagc
ctgcgctacgtggcgcccccaagcctgcgcatgccccctgacgtgcgggccttcgtggcc
tcccgtggcaccaagcaggaggaatttgagagcatcgaggaggcgctgcctgacaccgat
gtactctacatgacacgcatccagaaggagcgcttcggctccacccaggagtatgaagca
tgcttcggccagttcatcctcactccgcacatcatgacccgggccaagaagaagatggtg
gtgatgcacccaatgccccgtgtcaatgagatcagtgtggaggtggactcagacccccga
gcagcctacttccgccaggcagagaacggcatgtacatccgcatggctctgttggccacc
gtgctgggccgcttctag

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