Bos taurus (cow): 507481 Help Entry 507481            CDS       T01008                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism bta  Bos taurus (cow) Pathway bta01524   Platinum drug resistance bta04115   p53 signaling pathway bta04210   Apoptosis bta04215   Apoptosis - multiple species bta04217   Necroptosis bta04620   Toll-like receptor signaling pathway bta04621   NOD-like receptor signaling pathway bta04622   RIG-I-like receptor signaling pathway bta04623   Cytosolic DNA-sensing pathway bta04625   C-type lectin receptor signaling pathway bta04657   IL-17 signaling pathway bta04668   TNF signaling pathway bta04932   Non-alcoholic fatty liver disease bta04936   Alcoholic liver disease bta05010   Alzheimer disease bta05016   Huntington disease bta05022   Pathways of neurodegeneration - multiple diseases bta05132   Salmonella infection bta05134   Legionellosis bta05142   Chagas disease bta05145   Toxoplasmosis bta05152   Tuberculosis bta05160   Hepatitis C bta05161   Hepatitis B bta05162   Measles bta05163   Human cytomegalovirus infection bta05164   Influenza A bta05165   Human papillomavirus infection bta05167   Kaposi sarcoma-associated herpesvirus infection bta05168   Herpes simplex virus 1 infection bta05169   Epstein-Barr virus infection bta05170   Human immunodeficiency virus 1 infection bta05200   Pathways in cancer bta05203   Viral carcinogenesis bta05416   Viral myocarditis bta05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     507481 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     507481 (CASP8)    04215 Apoptosis - multiple species     507481 (CASP8)    04217 Necroptosis     507481 (CASP8)    04115 p53 signaling pathway     507481 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     507481 (CASP8)    04621 NOD-like receptor signaling pathway     507481 (CASP8)    04622 RIG-I-like receptor signaling pathway     507481 (CASP8)    04623 Cytosolic DNA-sensing pathway     507481 (CASP8)    04625 C-type lectin receptor signaling pathway     507481 (CASP8)    04657 IL-17 signaling pathway     507481 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     507481 (CASP8)    05203 Viral carcinogenesis     507481 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     507481 (CASP8)    05161 Hepatitis B     507481 (CASP8)    05160 Hepatitis C     507481 (CASP8)    05164 Influenza A     507481 (CASP8)    05162 Measles     507481 (CASP8)    05168 Herpes simplex virus 1 infection     507481 (CASP8)    05163 Human cytomegalovirus infection     507481 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     507481 (CASP8)    05169 Epstein-Barr virus infection     507481 (CASP8)    05165 Human papillomavirus infection     507481 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     507481 (CASP8)    05134 Legionellosis     507481 (CASP8)    05152 Tuberculosis     507481 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     507481 (CASP8)    05142 Chagas disease     507481 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     507481 (CASP8)    05016 Huntington disease     507481 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     507481 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     507481 (CASP8)    05416 Viral myocarditis     507481 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     507481 (CASP8)    04932 Non-alcoholic fatty liver disease     507481 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     507481 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:bta01002]     507481 (CASP8) Enzymes [BR:bta01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      507481 (CASP8) Peptidases and inhibitors [BR:bta01002]  Cysteine peptidases   Family C14: caspase family    507481 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  507481 NCBI-ProteinID:  NP_001039435 BGD-bta:  BT10840 Ensembl:  ENSBTAG00000015718 VGNC:  26784 UniProt:  Q2LGB8 LinkDB All DBs Position 2:89861821..89885546 Genome browser AA seq 485 aa AA seqDB search MALTQCLYNIGEQLGSDDLAALKFLSRDHIPYRKQEPIKDALMLFQRLQEKRMLEENNLS FLKELLFRVNRLDLLLNYLYTSEEEMKRELQIPGRAQISAYRILLFQISEDVNKVELKDF KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGEENLDTLKRICEQVNKSLLKKIYDYEE LRKERRMSLERDPYAFSNDMSQSLPEEGYSKMPAMSDSPEQDSELQTSDTVYRMTSKPRG YCLIFNNYDFSIARKQVPELHDLKDRTGTDFDADALDKTFRELHFEIVHYKDLTAKGICE VLESYQKKDHKNKDCFICCILTHGNKGIIYGSDGQEASIYELTSYFTGLKCPSLIGKPKI FFIQACQGDKYQKGVAVETDSEQMEAYLEVDSSPQKRYIPDEADFLLGMATVKNYVSYRN IWNGAWYIQSLCQNLRERCPRGEDILTILTKVNFEVSKLDDKQRMAKQMPQPTFTLRKKL FFPLN NT seq 1458 nt NT seq  +upstreamnt  +downstreamnt atggcgctcacccaatgtctctataatattggggagcagctgggcagtgacgacctggct gccctcaagttcctaagccgggaccacatcccatataggaagcaggaacccatcaaggat gccttgatgctattccagaggctccaagaaaagagaatgttggaggaaaacaatctgtcc ttcttgaaggagctgcttttccgagtgaatagactggatctgctgcttaactacttgtat accagcgaggaggagatgaagagggagcttcagatacccggcagggcccagatctctgcc tacaggattctgcttttccagatttcagaagatgtgaacaaagtagaattgaaggacttt aagttttttttgagccaggagattgccaaatgtaagctggatgatgacatgactttgctt gatattttcgtggagatggagaagaggaccatcctaggggaagagaacttggacaccctg aaaagaatctgtgagcaggtcaacaagagcttgctgaagaaaatctatgattatgaagaa ttaagaaaagagagaagaatgagccttgaaagagatccatatgcattttcaaatgacatg tcacaatcgcttccagaggagggctactctaagatgccggccatgtcagactctccagaa caggacagtgagttgcagacatctgacacagtttaccgaatgacaagcaaacctcgggga tactgtttgatctttaacaattatgattttagcatagcacggaagcaggtgcctgaactt cacgaccttaaggataggactggaacagactttgatgcagacgctttggataagaccttt cgtgaacttcattttgagatagtgcactacaaagacctaacagcaaagggaatctgtgag gttctagaatcctaccagaagaaggaccacaaaaacaaagactgcttcatctgctgcatc ctcacccacggaaacaagggcatcatctatggctccgatgggcaagaagcctccatctat gagctgacctcttacttcactggcttaaagtgcccttcccttattggcaaacccaaaatc ttttttattcaggcttgccaaggggacaagtaccagaaaggtgtagccgttgagaccgac tcagaacagatggaagcctatttagaggtggactcatcacctcagaagagatatatccca gatgaggctgactttctgctggggatggccactgtgaaaaactatgtttcctaccgaaac atctggaatggggcctggtatatccagtcactttgccagaatctgagagaaagatgtcct aggggtgaagacattctgaccatcctaaccaaggtgaacttcgaagtaagcaaactggat gacaagcaacgtatggccaaacagatgccacaacctactttcacactgcgaaaaaaactc ttctttcctcttaattga

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