Bos taurus (cow): 508431
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Entry
508431 CDS
T01008
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
bta
Bos taurus (cow)
Pathway
bta04120
Ubiquitin mediated proteolysis
bta04144
Endocytosis
bta04330
Notch signaling pathway
bta04668
TNF signaling pathway
bta04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
508431 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
508431 (ITCH)
04668 TNF signaling pathway
508431 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
508431 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
508431 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bta04131
]
508431 (ITCH)
04121 Ubiquitin system [BR:
bta04121
]
508431 (ITCH)
Enzymes [BR:
bta01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
508431 (ITCH)
Membrane trafficking [BR:
bta04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
508431 (ITCH)
Ubiquitin system [BR:
bta04121
]
Ubiquitin ligases (E3)
HECT type E3
508431 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
508431
NCBI-ProteinID:
NP_001075897
BGD-bta:
BT28819
Ensembl:
ENSBTAG00000000308
VGNC:
30307
UniProt:
A2VE03
LinkDB
All DBs
Position
13:63785090..63885035
Genome browser
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWEQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVVTL
QLVGDKEPAETIGDLSVCLDGLQLESEVVANGETACSESASHNDDGSRPKDETRANASGS
DDPEDAGSGENRRINGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTTSESD
GSSTGSLPPTNTNSSTSEGATSGLIIPLTISGGAGPRPLNPIPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagtttgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatgggagcagcctcttacagttattgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctggattg
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccagcagagacaataggagatttgtcagtctgtcttgat
gggctgcaactagagtctgaagttgttgccaatggtgaaactgcatgttcagaaagtgct
tcacacaatgatgatggctccaggcccaaggatgaaacaagagcgaacgcaagtggatca
gatgaccctgaggatgcagggtctggtgaaaataggaggatcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggctcaccatctaccacttctgaaagtgat
ggctctagtacaggctctctgccaccaacaaatacaaattcaagtacatctgaaggagca
acatctggattaataattcctcttactatatctggaggtgcaggccctagaccattaaat
cctatacctcaagctcccctcccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggagcggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacactggaatcagtccggaactatgaacaatggcag
ctccagcgtagtcaacttcagggagctatgcagcagtttaaccagaggttcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgccg
cctggttgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacggtagacggaattccgtattttgtggaccacaataga
agaacaaccacctatatagatccccgcaccggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcaatatttccgtttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtcctcaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaataaaccagttggactgaaggatttagaatcgattgat
ccagaattttacaattctctcatctgggttaaagagaacaatattgaggagtgtggtttg
gaaatgtatttctccgttgataaagaaatcttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggagattgtctcgtggtgttgaagaacagacgcaagctttctttgagggcttt
aatgaaattcttccccagcagtatttacagtacttcgatgcaaaggaattagaggttctt
ttatgtgggatgcaagagattgatttgaatgattggcaaagacatgccatctaccgtcac
tataccaggacaagtaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgcgacttttgcagtttgttactgggacctgccgactgccagttggagga
tttgctgacctcatggggagcaatgggccacagaagttctgcattgaaaaagtcgggaaa
gaaaattggttgcctagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgctattgaagaaacagaaggctttgga
caagagtga
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