KEGG   Bos taurus (cow): 508809
Entry
508809            CDS       T01008                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
bta  Bos taurus (cow)
Pathway
bta00670  One carbon pool by folate
bta00790  Folate biosynthesis
bta01100  Metabolic pathways
bta01240  Biosynthesis of cofactors
bta01523  Antifolate resistance
bta04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    508809 (DHFR)
   00670 One carbon pool by folate
    508809 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    508809 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    508809 (DHFR)
Enzymes [BR:bta01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     508809 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 508809
NCBI-ProteinID: NP_001071351
Ensembl: ENSBTAG00000007681
UniProt: P00376 A0A140T872
LinkDB
Position
7:complement(80733288..80748878)
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGNLPWPPLRNEFQYFQRMTTVSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPKGAHFLAKSLDDALELIEDPELTNKVDVVWIVGGSS
VYKEAMNKPGHVRLFVTRIMQEFESDAFFPEIDFEKYKLLPEYPGVPLDVQEEKGIKYKF
EVYEKNN
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccactaaactgcatcgttgctgtgtcccagaacatgggtatcggcaagaac
ggaaacctgccctggccaccgctcaggaatgaattccagtatttccagagaatgactaca
gtctcttcagtagaaggtaaacagaatttggtgattatgggtaggaagacctggttctcc
attccagagaagaatcgacctttaaaggacagaattaacatagttctcagtagagaactc
aaggaacctccaaagggagctcattttcttgccaaaagtctggatgatgccttagaactt
attgaagatccagaattaacaaataaagtagacgtggtttggatagtgggaggcagttct
gtttataaggaagccatgaacaagccaggccatgttagactatttgtgacaaggatcatg
caagaatttgaaagtgatgcgtttttcccagaaattgattttgaaaaatataaacttctt
ccagaatatccaggtgttcctttggatgtccaagaggaaaaaggcattaagtacaaattt
gaagtatatgaaaagaacaattaa

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