Bos taurus (cow): 514607 Help Entry 514607            CDS       T01008                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism bta  Bos taurus (cow) Pathway bta04022   cGMP-PKG signaling pathway bta04068   FoxO signaling pathway bta04081   Hormone signaling bta04140   Autophagy - animal bta04152   AMPK signaling pathway bta04211   Longevity regulating pathway bta04213   Longevity regulating pathway - multiple species bta04910   Insulin signaling pathway bta04920   Adipocytokine signaling pathway bta04923   Regulation of lipolysis in adipocytes bta04930   Type II diabetes mellitus bta04935   Growth hormone synthesis, secretion and action bta05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     514607 (IRS4)    04022 cGMP-PKG signaling pathway     514607 (IRS4)    04152 AMPK signaling pathway     514607 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     514607 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     514607 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     514607 (IRS4)    04923 Regulation of lipolysis in adipocytes     514607 (IRS4)    04920 Adipocytokine signaling pathway     514607 (IRS4)    04935 Growth hormone synthesis, secretion and action     514607 (IRS4)   09149 Aging    04211 Longevity regulating pathway     514607 (IRS4)    04213 Longevity regulating pathway - multiple species     514607 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     514607 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     514607 (IRS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH_11 Motif Other DBs NCBI-GeneID:  514607 NCBI-ProteinID:  XP_005227955 BGD-bta:  BT10405 Ensembl:  ENSBTAG00000006535 VGNC:  30285 LinkDB All DBs Position X:complement(57408199..57424624) Genome browser AA seq 1254 aa AA seqDB search MASCSFARDQATRRLRAAVAATAAGLAAAATTPFLSSGTPTALIGTGSSCPGAMWLSTAT GSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHWRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGATVPALIAPRRVITLYQCFSVSQRADARYPHLIALFTQNEYFAMV AENESEQESWYLLLSRLILESKRRRCGRLGAQPEGEPAALAAAAAAEPPFYKDVWQVIVK PRGLGHRKELSGVFRLCLTDEEVLFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGGHLLTLLSTRRH LDMLPLEPGGWFRRSRFEQFCHLRAIGDGEDEMLLAGRYITPSEPVPRSRRGRLHLPRGR RSRRATSVPASFFRHAAPSPVRIRYPAEALHDRDPESSEASSSGSGNSGEEGGPQRKEDQ EENEGDYMPMNNWGSGNGRGSGSGQGSSGQGSSSQSSGGSQCSGRGHGSGGGQGSSSSHG SSGSGSGDQSAGGNQCSGDGQGTAGHGSGSGQGAGGGHGSGRDQGAGDGHGSGGGKNSGG GKGSGSGKGPEGNGDRGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPGAATGGKGKSGGR FRLYFCADRGATKERKEAKEGKDTEPPEGAARGPHRARAFDEDEDDPYVPMRPGVAAPLA SSSDYMPMAPQNVSVSKKRHSRSPFEDSRGYMMMFPRVSPPPVPSPPKEPDPAKEDDSKD NDSDSDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQSDHSEYVPML PGKFLGKGLEKEVSSNRGPKDTASKPSVKGSFSKPRDGGSPSKRSGDGPPKNKAKRPNRL PFMTKGNKVKPKPQKPTQEQREADSPRGYVNIDFPKRGYNMPDPCLQRLPGVWGIIADPR QFAFSNYVNVEFGVPFPNPADNLSDFFRAIPGANPFFLDGATGSSANREEGDYIEVIFNP AMTPAVPFADSAIRYDAETGRIYVVDPFSECCMNISLSPSRCSERPPVARLLLLEELERR RPQSRSQSFFAAARAAISAFPTDSLERDLSASFAAAAAAVPTLALGRALAAASALVAAPG IGAAAAGLEAAAGFDSASVRWFLPVADAAGAAVRGAQDIAGGSNPRPPNPSADLAGGENR AGGAAAAVAAAPRSPGRGRVSRPPEREDSDDDDTYVRMDFARRDNGKFDSPQRE NT seq 3765 nt NT seq  +upstreamnt  +downstreamnt atggctagttgctccttcgctcgcgaccaagcgacaaggagactgcgagctgcagtagcg gcaacagcggcgggtctagctgcggcggcgaccaccccatttctttcctcgggaaccccc accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccact ggctcccggtcagactcggagtccgacgaggaggaccttcccgtcggggacgaagtctgc aaacgcggctacctgcggaagcagaagcatgggcactggcgctacttcgtgctcaaactc gagacagccgacgccccagctcggctggaatactacgaaaatgccaggaagttccggcac agtgtccgcgccgcggcggctgcagcggcggcggccgcctctggcgccacggtccccgcg ctcattgcaccgcggcgcgtgatcaccctgtaccagtgcttctcggtgagccagcgggcc gacgcaaggtacccacacctcatcgctcttttcacccaaaacgagtatttcgcaatggtg gcagagaatgagtcggagcaagagagctggtacttgctgctcagccgcctcatcctcgag agcaagcgccgccgctgcggcaggctcggcgcgcagccggagggagagccggccgcgcta gcagctgcagcggcggcagagccacccttctacaaagatgtgtggcaagtaatagtcaaa cccagggggctggggcaccgaaaagagctgagcggcgtgttccggctctgtcttaccgac gaggaggttctgttcgtgaggttaaataccgaagtggccagcgtggttgtccagctcctg agcatccgtcgctgtgggcactcggagcagtatttcttcttggaagtcggcaggtccacc gtcatcggtccgggggagctctggatgcaagtggatgactgtgtcgtggcccaaaacatg cacgagctgtttttggagaagatgagagccttgtgtgcagacgaatacagagcccgctgc cgcagctacagcatcagcatcggcggccacctgttaaccctgctgtccactaggaggcac ctggacatgctgccgctcgagcccggcggctggttccgaaggtcccgctttgagcagttt tgccaccttcgggccatcggtgacggggaagacgaaatgctcctcgccgggcgctacata acacccagtgagccagtgccccgctccagacgaggaagactacacctgcccagagggcgc agatccaggagagcgacttcagtgccagccagctttttccgccacgccgcacccagccct gtgcgcatccggtaccctgcagaagccctccacgaccgagatcccgagtcttctgaagcc tctagttctggctctggcaattcaggggaagaaggcggtcctcagcgcaaagaggatcag gaagaaaacgaaggtgactatatgcccatgaacaactggggctcgggaaatggccggggc tcaggaagtggacagggttcaagtgggcaaggctccagtagccaaagctccgggggaagt cagtgctcaggcagggggcatggctccggaggtggtcagggctcaagtagcagccatggc tcaagtggcagcggttccggggaccagagtgcaggaggaaaccagtgctctggggatggc cagggcaccgctgggcatggctcaggcagtggccagggagctggaggtgggcatggctca ggccgtgaccagggagccggagatggccatggctcaggcggtggcaagaactctggaggg ggcaaaggctcagggagtgggaaggggcctgaaggcaatggtgatcgtgggaaatctctg aagaaaagatcctactttggcaaattaactcaaagcaagcaacagcaaatgccaccacct ccgccccctccacccccaccaggtgcagcaactggtggcaaagggaagtctgggggaagg ttccgactttatttttgtgcagacagaggggccacaaaagaacgcaaagaagccaaagaa gggaaagacacagagcccccagaaggtgcagctcggggtccccacagagccagagctttt gatgaagacgaggatgatccatatgtgccaatgaggccaggcgtggctgctcctctcgca agctccagtgactacatgcccatggctcctcaaaatgtctctgtgtccaaaaagcgccac tctcgatcaccttttgaagattctagagggtacatgatgatgtttcccagagtgagccca ccacctgtgccaagtcctccaaaagaacctgatcctgctaaagaggatgactcaaaggac aatgacagtgacagtgactatatgttcatggcccctggagctggtgccattcctaaaaac cccagaaatcctcagggaggctcttcctccaaaagttggagctcctacttctctctgcca aatccttttcggagctccccattgggacagagtgaccacagtgagtatgtaccaatgtta cctggaaaattcctaggaaagggcctagagaaggaagtctcatctaacagaggccccaaa gatacagcttcaaagccttcagtcaaagggtctttctcaaagcctagagatgggggatca ccttccaagcgttcaggtgacgggccccccaagaacaaggctaagagacctaatcgactt ccttttatgacaaaaggaaacaaagtcaagccaaaaccacaaaagcccacacaggagcag agagaagccgacagccccaggggctacgtcaacattgacttccctaagagaggttataat atgccagatccatgtcttcaaagacttccaggtgtgtggggcataattgccgaccccaga cagtttgccttttccaattatgtgaatgttgagttcggagtgccatttccaaatccagca gacaacctctcagatttcttcagagctatcccaggtgccaatcccttctttctggacggt gctaccgggagcagtgctaatagggaagaaggtgactacatcgaagtgattttcaaccca gcgatgacaccagccgtgccttttgctgacagtgccattcgctacgatgccgaaactggt cgcatctacgtggtcgacccattttctgagtgctgtatgaacatttctctctcccccagc cgctgctccgaacgaccacctgtagcgaggctgctactgctagaagagctcgagcgaagg cgcccacaaagccgttcgcaaagtttctttgcagccgccagagccgccatctctgctttc cctacagacagcctcgagagagacctatccgcctccttcgccgcggccgcggccgccgtg ccaaccttagccctgggccgggctttagccgccgcctccgctttggtcgcggctcccggc atcggcgcagcagccgccggcctcgaggccgccgctggatttgactccgcctccgtccgc tggttcctacctgttgccgatgctgctggtgccgcggtcaggggggcccaagacattgcg ggtggctcgaaccccagacccccaaacccatcagcagacctggccggaggtgagaaccga gccggtggggctgctgctgcagtcgccgctgcgcctcgatcacctggccgcggccgggtg tccagacccccagagcgagaagattctgacgacgacgacacgtacgtgagaatggacttt gcaagacgtgacaacgggaagttcgactctccccaaagagagtga

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