Bos taurus (cow): 515338 Help Entry 515338            CDS       T01008                                  Symbol ACACB Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism bta  Bos taurus (cow) Pathway bta00061   Fatty acid biosynthesis bta00620   Pyruvate metabolism bta00640   Propanoate metabolism bta01100   Metabolic pathways bta04152   AMPK signaling pathway bta04910   Insulin signaling pathway bta04920   Adipocytokine signaling pathway bta04922   Glucagon signaling pathway bta04931   Insulin resistance bta04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:bta00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     515338 (ACACB)    00640 Propanoate metabolism     515338 (ACACB)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     515338 (ACACB)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     515338 (ACACB)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     515338 (ACACB)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     515338 (ACACB)    04922 Glucagon signaling pathway     515338 (ACACB)    04920 Adipocytokine signaling pathway     515338 (ACACB)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     515338 (ACACB)    04931 Insulin resistance     515338 (ACACB) Enzymes [BR:bta01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      515338 (ACACB)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      515338 (ACACB)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      515338 (ACACB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C Motif Other DBs NCBI-GeneID:  515338 NCBI-ProteinID:  NP_001192262 BGD-bta:  BT28796 Ensembl:  ENSBTAG00000022058 VGNC:  25520 UniProt:  Q50I03 Q50HZ7 Q50I02 Q50HZ8 Q50I04 Q50I01 LinkDB All DBs Position 17:complement(63845551..63960652) Genome browser AA seq 2431 aa AA seqDB search MSDSKQVTKSKRKVSFTPSQEPIPASEGSQEPPQEDCNSSPLPKTPSQAELASHKGPQDT CQQRPSQSPLPQNPQGNPLSSDDASPARQANGSETEGPEIPNTNDLSAPARPQGQRARTL SREDRKQAHIKRQLMTNFILGSFDDNSSDEDAGAALFRQSSRKGSRASLGTLSLETAHAA GETETCAPVIRPSMSGLHLARRGREQKKVDLHRDFTVASPAEFVTRFAGHLVIEKVLIAN NGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNN NYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLRKHEIAFLGPPSEAMWALGDKIA STIVAQTLQIPTLPWNGSGLTVEWAEHSLQEGQRISIPESVYNNGCVKDVDEGLEAAEKI GFPLMIKASEGGGGKGIRKAETAEDFPILFRQVQSETPGSPVFLMKLAQRARHLEVQILA DQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAGTVE YLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESP WGVTPISFETPSNPPIPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVA ATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLTNLLETENFQ NNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNVADSMFRTCMTDFLHSLERGQVLPAD SLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNGSHIEIDAHRLNDGGLLLSCSGNSYT TYLKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLVKYTVADGEHVEAGGSYAEIEV MKMTTTLNVQESGRVKYVRRPGAVLEAGCVVARLELDDPSKVRPAEPFTGELPSQPTLPI LGEKLHQVFHSVLENLTNIMNGYCLPEPIFSIKLKDWVQKLLRALRHPSLPLLELQEIMT SVSGRVPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMN TQSIVQLVQKYRSGARGYMKAVVLDLLRRYLLVEHHFQQAHYDKCVINLREQLKPDMAQV LDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELTSILDELTQLSKSEHCKVALRARQV LIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKV VCMASLEVYVRRGYIAYELTSLQHRQFPDGTCVVEFQFMLPSSHPHRMTVPISVTNPELL RHSTELFMDSGFSPKSQRMGAMVAFQRFEDFVRNFDEVISCFANMPKDTPLFSEARNSLY SEDDSKSLREEPIHILNVALQHADHQEDEQLVPIFRTFVQSKKNILVECGLRRITFLIAQ EKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRLRNFDVTAMPCANHKMHLYLGAA RVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRT DCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTADSAIPI RLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNKQGPQHGMLINTPYVTKDLLQAKRF QAQSLGTTYVYDFPEMFRQALFKMWPSPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNE VGMVAFKMTLKTLEYPEGRDIILISNDITFRIGSFGPGEDLLYLRASELARAEGIPRVYL AANSGARIGLAEEIKHMFQVAWVDPEDPHKGIKYLYLTPQDYTRISSLNSVHCKHVEEDG ESRYVITDIIGKEEGLGVENLRGSGMIAGETSQDYDEIVTISMVSCRALGIGAYLVRLGQ RVIQVENSHIILTGATALNKVLGRDVYTSNNQLGGVQIMHHNGVSHVTVPDDFEGVCTIL EWLSYMPKDNRSPVPVVTPKDPIDREIEFQPSRGPYDPRWLLAGRPHPTLKGSWQSGFFD QGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETRTVELVVPADPANLDSEAKIIQQAGQ VWFPDSAYKTAQAIKDFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRKYRQ PVLIYIPPYAEVRGGSWAVMDTSINPLCIEMYADRESRASVLEPEGTVEIKYQKKDLVKT IRRLDPISKKLVEQLGVSELSDTDRKELEGQLKAREDLLLPMYHQVALHFADLHDTAGRM LEKGVIYDILEWKTARSFLYWRLRRLLLESQVKQEVLRACPELSHMHVQSMLRRWFVETE GAVKAYLWDNNQTVVQWLEAHGQASEGLHSTIRENITCLRRDSALKTIQGLVQENPELAM DSLVYVSQHISPAERAQVIHLLSTTDGPAST NT seq 7296 nt NT seq  +upstreamnt  +downstreamnt atgtcagactccaagcaagtcaccaagagtaaacggaaagtgagcttcaccccgagtcag gagccgattccagcctcagagggatcccaggagccaccgcaggaagactgcaacagcagc cctctgccaaagacccctagccaggctgagctggcctcccacaaaggaccccaagacacc tgccagcagaggccctcccaatcacctctgccacagaatccccaaggaaaccccctctcg tctgatgacgcctccccagcacgccaagccaacgggtcagagactgaaggcccggagatc ccaaataccaatgacctgtccgcgccagccaggccccagggccagcgagccagaaccctc tccagagaagacaggaagcaggcacacatcaagagacagctgatgaccaacttcatcctg ggctcttttgatgacaactcctccgatgaagatgctggtgctgccctgttccgacagtct tcccggaagggcagccgggccagcctggggaccctgtccctggagactgctcatgccgca ggcgagactgagacctgtgcccccgttataaggcccagcatgtcggggctccacctggca agaaggggccgagaacagaagaaagtggacctgcacagagacttcaccgtggcttcccct gctgagttcgtcacacgctttgcggggcatctggtcatcgagaaggtgctcatcgcgaac aacggtattgccgccgtgaaatgcatgcgctccatccgcaggtgggcctatgagatgttc cgaaatgagcgggccatccggttcgtagtcatggtaacgccagaggacctcaaggccaac gcagagtatatcaagatggcagatcagtatgtccctgtcccaggagggcccaacaacaac aattacgccaacgtggagctgattgtagacatcgccaagaggatccccgtgcaggcggtg tgggctggttggggccatgcttctgaaaaccccaaacttccggagctcctgcgcaagcac gagattgctttcctaggccctcccagcgaggccatgtgggcactaggagacaagattgcc tccaccatcgtggcccagactctgcagatcccaacgctgccctggaacggaagtggtctg acggtggagtgggcggaacacagtctacaggaggggcaaaggatcagcatcccagagtcc gtctacaacaatggttgcgtgaaagatgtagatgaaggcttggaggcagcagaaaaaatt ggttttcccttgatgatcaaagcttctgaaggcggtggagggaaaggaatccggaaggcg gagactgctgaggacttccccatcctgttcagacaagtgcagagcgagacccctggctcc ccagtcttcctcatgaagctggcccagcgtgcccggcacctggaggtccagatcctcgcc gaccagtacgggaacgcagtgtccctgttcgggcgtgactgttccatccagcggaggcac cagaagatcatagaggaggcgccggccaccattgccacgccagccgtgttcgagttcatg gagcagtgtgccgtgcgcctggccaagacggtgggctacgtgagcgcggggactgtcgag tacctttacagccaggatggcagcttccacttcttggagctgaatccccgcctgcaggtg gaacatccctgcacggaaatgatcgcggatgtcaacctgcctgctgcccagctgcagatt gccatgggtgtgccgctgcaccggctgaaggatatccggcttctgtacggagagtccccg tggggggtgacgcccatttcttttgagacccctagcaaccctcccattccccgaggccac gtcattgcagccagaatcaccagcgaaaacccagatgaggggtttaagccgagctccgga acggtccaagaattgaatttccgcagcagcaagaatgtatggggttatttcagcgtggct gcgactggtggcttacacgaatttgcggattcccagtttgggcactgcttttcctggggg gagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactatccatcagg ggcgacttcaggaccaccgtggaatatctcaccaaccttctggagactgagaactttcag aacaacgacattgacaccagctggttggataacctcattgctgagaaagtgcaggctgag aagccagatatcatgctcggggttgtgtgcggagccttgaacgtggccgactccatgttt agaacatgcatgacggacttcctacactcgctggaaaggggccaggtcctccccgcagac tctctgctgaacatcgtggacgtggaattaatctatggaggtgtcaagtacattctcaag gtggcccggcagtctccgaccatgttcgtgctcatcatgaacggctctcacatcgagatc gacgcccaccggctgaacgacggggggctactgctgtcctgcagcggcaacagctacacc acctacctgaaggaggaggtggacagttaccgaatcaccattggcaacaagacgtgcgtg tttgagaaggagaatgaccccacagtcctgagatccccttcggctgggaagctggtgaag tacactgtggcagacggggaacacgttgaggctgggggcagctacgccgagatagaggtc atgaagatgaccacgaccctgaacgtgcaggaaagtggccgggtgaagtatgtcaggcgc ccgggggctgtgttggaagctggctgcgtggtggccaggctggagctcgatgacccttct aaagtgcgcccggctgagccgttcacgggggagctcccctcacagcccacgctgcccatc ctcggagagaagctgcaccaggtttttcacagcgtcctggaaaatctcaccaacatcatg aatggctactgtctgccggagcctatttttagcatcaagctgaaggactgggtgcagaag ctcctgagggccctccggcacccgtcgctgccgctgctggagcttcaggagatcatgacc agtgtgtcgggccgcgttcccgcccccgtggagaaggccgtccgcagggtgatggcccag tacgccagcaacatcacctcggtgctctgccagttccccagccagcagatagccaccatc ctggactgccacgcagccaccctgcagcggaaggccgaccgggaggtcttcttcatgaac acccagagcattgtacagctggtccagaagtaccgcagtggggcccgcggctacatgaag gcggtggtcttggacctcctgcggagatatttactggttgagcaccatttccagcaagcc cactacgacaagtgtgtgataaacctccgggagcagctgaagccagacatggcccaggtg ttggactgcatcttctcccactcgcaggtggccaagaagaaccagctggtgatcatgttg attgatgagctctgtggcccagacccatccctgtccgatgagctgacctccatcctcgac gagctgactcagctgagcaaaagcgagcactgcaaggtggccctcagagccaggcaggtc ctgattgcctcccatctcccctcctacgagctgaggcacaaccaagtggagtccattttc ctgtctgccattgacatgtacggccaccagttctgcccagaaaacctcaagaaattaata ctctcagaaacaaccatctttgatgtgctgcccactttcttctaccacgctaacaaagtg gtttgcatggcatccttggaggtctatgtgcggaggggctacatcgcctatgagctaacc agcctgcagcaccgccagttcccggatggcacctgcgtggtggaattccagttcatgctg ccctcctcccacccgcaccggatgaccgtgcccatcagtgtcaccaacccggaactgctg agacacagcacggagctctttatggacagtggcttctcccccaagtcccagcgaatgggg gccatggtcgccttccagagattcgaggatttcgtcaggaactttgatgaggtcatctcc tgctttgccaacatgcccaaggacacccccctcttcagcgaggcccggaattccctgtac tctgaggacgacagcaagagcctccgagaggagccaatccacatcctaaatgtggccctc cagcacgcggaccaccaggaggatgagcagctggtgcccattttccgaacattcgtgcag tccaagaaaaacatccttgtggagtgtggactccgaagaatcacattcctgattgcccaa gagaaagaatttcccaagtttttcacattcagagcaagagatgagtttgcagaagatcgc atctaccgtcacttggagccggccctggccttccagctggagctcagccggttgcgaaac ttcgacgtgaccgccatgccctgcgccaaccacaagatgcacctgtacctgggtgccgcc agagtgaaggagggcgccgaggtcacggaccacaggttcttcatccgggtcatcatcagg cactcagacctgatcaccaaggaagcctccttcgagtacctccagaacgagggcgagcgg ctgctcctggaggccatggacgagctggaggtggcattcaacaacaccagcgtgcgcaca gactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggacccctccaagatt gaggagtcggtgcggtccatggtgatgcgctacggcagccgcctctggaagctccgcgtg ctccaggctgaggtcaagatcaacatccgccagaccaccgccgacagcgccatccccatc cgcctcttcatcaccaacgagtcaggctactacctggacatcagcctctacaaggaagtg accgaccccagatctggaaacatcttgtttcactcctttggcaacaagcaaggcccccag catgggatgctgatcaacactccctatgtcaccaaggatctgcttcaggccaagcgattc caggcccagtccctgggtaccacctatgtgtatgacttcccagaaatgttcaggcaggct ctttttaaaatgtggccctctccggacaagtaccccaaagacatcctgacgtacaccgaa ctcgtgctggatccgcagggccagctggtggagatgaaccgacttcctggaggaaatgag gtgggcatggtggccttcaaaatgacgttgaagaccctcgagtaccccgaagggcgtgac attatcctcatcagcaatgacatcaccttccgtatcggatcctttggccccggagaagac cttctgtacctgcgggcgtctgagctggcccgggccgagggcatccccagagtctacctc gcggccaacagtggggcccgtatcggcctggcagaggagatcaagcacatgttccaggtg gcttgggtggacccggaagacccccacaagggaattaaatacctgtacctgaccccccaa gactacaccagaatcagctccctgaactccgtccattgtaaacacgtggaggaagatgga gaatccaggtatgtcatcacggacatcattgggaaggaggagggcctgggcgtagagaac ctgaggggctcaggcatgattgctggggagacctcccaggactacgacgagatcgtcacc atcagcatggtgagctgccgggccctcgggatcggggcctacctggtgaggctgggccag cgagtgatccaggtggagaattcccacatcatcctcacgggggcgacggcgctcaataag gtcctgggcagagacgtttacacgtccaacaaccagctgggcggtgtgcagatcatgcat cacaatggcgtctcgcatgtcaccgtgccagatgactttgagggtgtttgtaccatcctg gaatggctgtcctatatgccaaaggataatcgcagcccagtcccagtcgtcacacccaag gaccccattgacagagaaattgaattccaaccatctcgcgggccctacgacccccggtgg ctgcttgcaggaagacctcacccaactctgaagggatcctggcagagtggattctttgac cagggcagtttcaaggagatcatggtgccctgggcccagactgtggtgacgggacgagca aggctggggggtatccccgtcggagtgatagctgcagagacgcggacggtggagttggtt gtgcccgccgaccctgccaacctggattccgaggccaagataatccagcaggctggccag gtgtggttcccagattcggcctataagacggcccaggccatcaaggatttcaaccgggag aagttgcccctgatgatctttgccaactggagggggttctccgggggcatgaaagacatg tatgaccaggtgctaaagttcggagcctacatcgtggatggcctccggaagtacagacag cccgtcctgatctacatcccgccctatgcggaggtccggggcggctcctgggcagtcatg gacacctccatcaacccgctgtgcatagagatgtacgcggacagagagagcagagcaagt gttctggagccagagggaacagtggagattaagtaccagaagaaagatctggtgaagacc atcagaagactcgaccccatttccaagaagctcgtggaacagctcggagtgtctgagctc tcagacacggaccgcaaggagctggagggccagctgaaggcccgggaggacctgctgctg cccatgtaccaccaggtggcgctgcactttgccgacctccacgacacggcgggcaggatg ctggagaagggcgtcatttacgacatcctggagtggaagacggcccgcagcttcctgtac tggcgcctgcgccgcctgctgctggagagccaggtgaagcaggaggtcctgagggcctgc cccgagctcagccacatgcatgtgcagtccatgctgcgccgctggtttgtggagacggag ggcgctgtcaaggcctacctgtgggacaacaaccagacggtggtgcagtggctggaggcg cacgggcaggcgagcgaggggctgcactccaccatccgggagaacatcacgtgcctgagg cgggactccgccctcaagaccatccagggcctggttcaagaaaaccccgagctggccatg gactcactggtgtacgtcagccagcacatcagcccggccgagcgggcccaggtcattcac ctcctgtccaccacggacggcccggcctctacctga

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