Bos taurus (cow): 515924
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Entry
515924 CDS
T01008
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret precursor
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
bta
Bos taurus (cow)
Pathway
bta04010
MAPK signaling pathway
bta04020
Calcium signaling pathway
bta04151
PI3K-Akt signaling pathway
bta05200
Pathways in cancer
bta05216
Thyroid cancer
bta05223
Non-small cell lung cancer
bta05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
515924 (RET)
04020 Calcium signaling pathway
515924 (RET)
04151 PI3K-Akt signaling pathway
515924 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
515924 (RET)
05230 Central carbon metabolism in cancer
515924 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
515924 (RET)
05223 Non-small cell lung cancer
515924 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bta01001
]
515924 (RET)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
515924 (RET)
Protein kinases [BR:
bta01001
]
Receptor tyrosine kinases (RTK)
RET family
515924 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
Pkinase
RET_CLD3
RET_CRD
Cadherin
Pkinase_fungal
RIO1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
515924
NCBI-ProteinID:
NP_001178412
Ensembl:
ENSBTAG00000000570
VGNC:
33876
LinkDB
All DBs
Position
28:13467125..13524201
Genome browser
AA seq
1072 aa
AA seq
DB search
MAKATASTVGLRLLLLLLPLLGEAPLGLYFSRDAYWEKLYVDQPAGTPLLYVHALRDVPE
EVPSFRLGQHLYGAYRTRLHENDWVRIQEDTGLLYLNQSLDHSSWEKLNIRNGGFPLLTV
YLWVFLSPASVREGECQWPGCARVYFSVINASFPACGALKPRELCFPESGLSFRIRENRP
PGTFHQFRLLPVQFLCPNVSVAYRLLGGESLPFRCDPDSLEVSTRWALDREQREKYELVA
ACTVRVGAREEEVMVPFPVTVYDEDDSAPTFLGGVDSASAVVEFKRKEGTVVATLRVFDA
DVVPASGELLRRYTNTLLSGDPKALRTFRVEHAPNETLAQANGSFVRATVHDYKLVLNRS
LPISESWAVQLAVLVNDSDFQGPGEGVVLLHFNVSVLPVSLRLPSAYSFSVSRRAHRFAQ
IGKVCVENCQEFSGIQVQYRLQPSSANCSALGMVTSAEDTSGTLFVNDIEALQRPECAQL
QYTVVAAEKPTRQQAQAPLLVSVEGIYVPEEPGCPLSCAVSKRRPECEECGGLGSLTGRC
EWRQGDGKGITRNFSTCSPSIRTCPDGHCDAVESRDPNICPQDCLRGGSIIGGHEPGERR
GIKAGFGICNCFPEEKKFFCEPEDSQDSLCDELCRTVITAAVLFSFIVSVLLSTFCIHRY
HKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDTFKIPEDPKWEFP
RKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLK
QVNHPQVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRNSSYLDN
PEERALTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNVLVAEGRRMKISDFGLSRDVY
EEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL
FNLLKTGYRMERPDNCSEEMYNLMLQCWKQEPDKRPVFADIGKDLDKMMVKSRDYLDLAA
STPSDSLLYDDGLSEEETPLVDCNNAPLPRTLPSTWIENKLYGRISHAFTRF
NT seq
3219 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggccagcaccgtggggctgcggttgctgcttctgctgctgcccctg
ctcggcgaagccccgctgggactctacttctccagggatgcttactgggagaagctatac
gtggaccagccggccggcacgcccctgctctatgtccacgccctgcgggacgtgccggag
gaggtgcccagcttccgcctgggccagcacctctacggcgcctaccgcacgcggctgcac
gagaacgactgggtccgcatccaggaggacacggggcttctctaccttaaccagagcctg
gaccacagctcctgggagaagctcaacatccgcaacggcggcttcccactgcttaccgtc
tatctctgggtcttcctgtcacccgcgtccgttcgtgagggcgagtgccagtggccgggc
tgtgcccgtgtgtacttctccgtcatcaatgcctccttcccagcttgcggcgccctcaaa
ccccgggagctctgcttccccgagtcaggcctgtccttccgcatccgggagaacaggccc
cccggcaccttccaccagttccgcctgctgcccgtgcagttcctctgccccaacgtcagc
gtggcctacaggctcctgggaggtgagagtctgcctttccgctgcgatccggacagcctg
gaggtgagcacgcgctgggccctggaccgcgagcagcgggagaagtatgagctggtggcc
gcgtgcacggttcgcgtgggcgcgcgcgaggaggaggtgatggtgcccttccccgtgacc
gtgtacgacgaggacgactctgcgcccaccttcctcgggggcgtcgacagcgccagcgcc
gtggtggagttcaagcggaaggagggcacagtggtagccacgttacgtgtcttcgatgca
gacgtggtgccagcctccggggagctcctgagacggtacacgaacacgctgctctctggg
gaccccaaggccctccggaccttccgagtggagcacgcgcccaatgagaccttggcccag
gccaacggcagctttgtgagggcaaccgtgcatgactacaagctggttctcaaccggagc
ctccccatctcggagagctgggctgtgcagctggccgtgctggtcaacgactcagacttc
cagggcccaggggagggtgtcgtcctcctccacttcaacgtgtccgtgctgcccgtcagc
ctgcgcctgcccagcgcctactccttctccgtgagcaggcgggcccaccgcttcgcccag
atcgggaaagtctgcgtggaaaactgccaggagttcagcggcatccaagtgcagtacagg
ctgcagccctccagcgccaactgcagcgccctggggatggtcacctcggctgaggacacc
tcggggaccctgttcgtgaatgacatagaggccctgcagcggcccgagtgtgcccagctc
cagtacacggtggtggccgccgagaaaccaacccgccagcaagcccaggccccgctgctc
gttagcgtggaagggatatacgtgcctgaggagcctggctgccccctgtcctgcgcggtc
agcaagaggcggcccgaatgtgaggaatgcggcggcctgggctctctaacgggcaggtgc
gagtggagacagggagacggcaaagggatcaccaggaacttctccacctgctcccccagc
atcaggacctgccccgatggccactgtgacgccgtggagagcagagaccccaacatctgc
ccccaggactgcctccggggcggcagcatcattggtgggcacgagcctggggagcgccgg
gggattaaagctggcttcggtatctgcaactgcttccctgaggagaagaagttcttctgc
gagccagaggacagccaggactccctgtgtgatgagctctgccgcacagtgatcacggcg
gccgtgctcttctccttcatcgtgtctgtgctgctgtccacgttctgcatccaccgctac
cacaagaacgcccacaagccgcccattgcctcggccgagatgaccttccgccggcccgcc
caagccttcccggtcagctactcctcgtctggcgcccgccggccctctctggactccatg
gagaaccaggtctcggtggacaccttcaagatcccggaggatcccaagtgggaattccct
cggaagaacttggtgcttggaaaaactctgggagaaggcgaatttggaaaagtggtcaag
gccacagccttccggctgaaaggcaaagcggggtacacgactgtggctgtgaagatgctg
aaagagaatgcctccccaagcgagctgcgggacctgctatcagagttcaacctcctgaag
caggtcaaccacccgcaagtcatcaagctgtacggggcctgcagccaggacgggccactg
ctcctcatcgtggagtatgccaagtacggctccctgcggggcttcctccgagagagccgc
aaggcggggcctggctacgtgggcagcgggggcagccgcaattccagttacctggacaac
ccggaggagcgggccctgaccatgggcgacctcatctcctttgcctggcagatctcacga
gggatgcagtacctggctgagatgaagcttgtccatcgggacttggcagccagaaacgtc
ctggtagctgagggccgcaggatgaagatctcagattttggtctgtcccgagatgtttat
gaagaggattcctatgtgaagaggagcaagggtcggatcccagtcaagtggatggccatt
gagtccctcttcgatcatatctataccacccagagtgatgtgtggtcctttggcgttctg
ctgtgggagattgtgaccctgggcggcaacccctaccctgggattcctccagagcggctc
ttcaaccttctgaagacaggctaccggatggagaggccggacaactgcagtgaggagatg
tacaatctgatgctgcagtgctggaagcaggaaccagacaagaggccagtgtttgccgac
atcggcaaagacctggataagatgatggttaagagcagagactacctggacctggccgcg
tccaccccatctgactccctgctgtatgacgacggcctgtcggaggaggagacgcccctg
gtggactgtaataacgctcccctccctcgcaccctcccctccacgtggattgaaaacaaa
ctctatggtagaatttcacatgcatttactagattctag
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