KEGG   Bos taurus (cow): 533729
Entry
533729            CDS       T01008                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
bta  Bos taurus (cow)
Pathway
bta04010  MAPK signaling pathway
bta04012  ErbB signaling pathway
bta04014  Ras signaling pathway
bta04024  cAMP signaling pathway
bta04062  Chemokine signaling pathway
bta04360  Axon guidance
bta04392  Hippo signaling pathway - multiple species
bta04510  Focal adhesion
bta04625  C-type lectin receptor signaling pathway
bta04650  Natural killer cell mediated cytotoxicity
bta04660  T cell receptor signaling pathway
bta04666  Fc gamma R-mediated phagocytosis
bta04810  Regulation of actin cytoskeleton
bta05132  Salmonella infection
bta05170  Human immunodeficiency virus 1 infection
bta05205  Proteoglycans in cancer
bta05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    533729 (PAK1)
   04012 ErbB signaling pathway
    533729 (PAK1)
   04014 Ras signaling pathway
    533729 (PAK1)
   04392 Hippo signaling pathway - multiple species
    533729 (PAK1)
   04024 cAMP signaling pathway
    533729 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    533729 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    533729 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    533729 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    533729 (PAK1)
   04660 T cell receptor signaling pathway
    533729 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    533729 (PAK1)
   04062 Chemokine signaling pathway
    533729 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    533729 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    533729 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    533729 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    533729 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    533729 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bta01001]
    533729 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    533729 (PAK1)
   03036 Chromosome and associated proteins [BR:bta03036]
    533729 (PAK1)
Enzymes [BR:bta01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     533729 (PAK1)
Protein kinases [BR:bta01001]
 Serine/threonine kinases: STE group
  STE20 family
   533729 (PAK1)
Membrane trafficking [BR:bta04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    533729 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    533729 (PAK1)
Chromosome and associated proteins [BR:bta03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     533729 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 533729
NCBI-ProteinID: NP_001070366
BGD-bta: BT21063
Ensembl: ENSBTAG00000010191
VGNC: 53657
UniProt: Q08E52
LinkDB
Position
29:18521574..18682812
AA seq 544 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRAILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKAVSETPAVPPVSEDEDDD
DDGTPPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaaataacggcctagacattcaagacaaacctccagcccctccgatgagaaatacc
agcactatgattggagctggcagcaaagacgctggaaccctaaaccacggttccaaacct
ctgccaccaaacccagaggaaaagaaaaaaaaggaccgattttaccgagccatcttacct
ggagataaaacaaataaaaagaaggagaaggaacggccagagatttctcttccttcagat
tttgagcacacgattcatgttggttttgatgctgtcacaggcgagtttacagggatgcca
gagcaatgggcccgcttgcttcagacatcaaatatcactaagtcggagcagaagaaaaac
ccgcaggctgttctggatgtgttggaattttataactcaaagaagacctccaacagccag
aagtatatgagctttacagataaatcagctgaggattataattcttctaacactttgaat
gtgaaggcggtgtctgagacccctgcagtgccaccagtttcagaagatgaagatgatgat
gatgatggcaccccacccccagtgattgctccacgcccagagcacacaaaatctgtatac
acacggtctgtgattgaaccacttcctattactccaactcgggatgtggctacatctccc
atttcacctactgagaataataccactccacctgatgctctgactcggaatactgagaag
cagaagaagaagcctaagatgtctgatgaggagatcttggagaaattacgcagcatagtg
agtgtgggtgatcctaagaagaaatacacacggtttgagaagattggacaaggtgcttcg
ggcactgtgtacactgcaatggatgtagccacaggacaggaggtggccattaagcagatg
aaccttcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagttaccttgtgggagatgagctatgg
gttgtcatggaatatttggctggaggttctttgacagacgtggtaacagaaacttgcatg
gacgaaggtcagattgcagctgtgtgccgtgagtgcctgcaagctttggagtttctgcat
tcgaaccaagttattcatagagacatcaagagtgacaacatcctgttgggaatggatggc
tctgtcaagttaactgattttggattttgtgctcagatcaccccagagcagagcaaacgg
agcaccatggtgggaacaccgtactggatggcaccagaggttgtaacccggaaagcctat
gggcctaaggttgacatttggtccttgggcatcatggccattgaaatgattgaaggggag
cccccatacctcaacgaaaaccctctgagagccttgtacctcattgccaccaatgggacc
ccagagcttcagaacccagagaagctgtcagctatcttccgagactttctgaaccgctgt
cttgagatggatgtggagaagagaggttcggctaaagaactgctgcagcatcaatttctg
aagattgccaagcctctctccagcctcactccactgattgctgctgcaaaggaagcaacc
aagaacaatcactaa

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