Bos taurus (cow): 535820
Help
Entry
535820 CDS
T01008
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 precursor
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
bta
Bos taurus (cow)
Pathway
bta04137
Mitophagy - animal
bta04140
Autophagy - animal
bta04141
Protein processing in endoplasmic reticulum
bta04210
Apoptosis
bta04932
Non-alcoholic fatty liver disease
bta05010
Alzheimer disease
bta05012
Parkinson disease
bta05014
Amyotrophic lateral sclerosis
bta05020
Prion disease
bta05022
Pathways of neurodegeneration - multiple diseases
bta05160
Hepatitis C
bta05162
Measles
bta05168
Herpes simplex virus 1 infection
bta05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
535820 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
535820 (EIF2AK3)
04137 Mitophagy - animal
535820 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
535820 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
535820 (EIF2AK3)
05162 Measles
535820 (EIF2AK3)
05168 Herpes simplex virus 1 infection
535820 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
535820 (EIF2AK3)
05012 Parkinson disease
535820 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
535820 (EIF2AK3)
05020 Prion disease
535820 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
535820 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
535820 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
535820 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bta01001
]
535820 (EIF2AK3)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
535820 (EIF2AK3)
Protein kinases [BR:
bta01001
]
Serine/threonine kinases: Other
PEK family [OT]
535820 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
535820
NCBI-ProteinID:
NP_001091555
BGD-bta:
BT22227
Ensembl:
ENSBTAG00000000184
VGNC:
28382
UniProt:
A5D791
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:47433953..47515741
Genome browser
AA seq
1115 aa
AA seq
DB search
MERATGPGSLARTLLLPLLLGLVAGTVTARRTSDLLAPTAEAAFGLGAAAAPTSATRVPA
TGAVIAAEVTVEDSEALPAAAGEQEAREPEPEPEEEPDIRPCGRSLVIISTLDGRIAALD
PENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVE
SLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDEMEQEEDILLLQ
RTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEQSKIISDVE
EQEAVMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDT
SYAPNDGVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVSS
ENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNG
YYLPYYKRERNKRSTQITVRFLDNPNYKNIRKKDPVLLLHWWKEIVGTIVFCIVATTFIV
RRLFHPHPHRQRKESETQCQTENKYDAVSGEANDSSWNDIKNSGYVSRYLTDFEPIQCMG
RGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLE
APPEKWQEKMDEIWLKDDSTDWPLSSPSPVDAPSVKIRRMDPFSTKECIEIIAPSPHSSR
SFSVGISCSQTSSSESQFSPLEFSGMDHGNVSKSADAVCQLQDSCLTDCEGEDGTMDGND
EGHSFELCPSEASPYIRSRERTSSSIVFEDSGCDNASSKEEPRMNQPPVGNHYANKLSAL
RHSGSKSSEPTVSVSPSRPTTLSLDLTKSSVGKLQPSSPKVYLYIQMQLCRKENLKDWLN
SRCTIEARERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTA
MDQDEEDQMVLTPMPGYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPF
GTQMERVRILTDVRDLKFPPLFAQKYPREYAMVQDMLSPSPTERPEAASIIENAIFEDLE
FPEKTLLRQRSRSMSSPGAKHSRHSSSPHSPLPSN
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccaccggcccggggtcgctggcacggacgctgctactgccgctgctgctg
gggctcgtggctgggacagtgaccgcgcggcgcacctctgacctcctcgcaccgacagcg
gaggcggcgttcggccttggggccgcggcggctcccacctcggctacgcgggtgccggcg
acgggagccgtgattgcagccgaagtgacggtggaggactccgaggcgctgccggcggct
gcaggcgagcaggaggcgcgggagccggagccggagccggaagaggagcccgatattcgg
ccgtgcggcagatcattagtgatcatcagcactttagatggccgaattgctgccttggat
cctgagaatcatgggaaaaagcagtgggatttggacgtggggtctggttccttggtgtca
tccagccttagcaaaccagaggtatttgggaacaagatgatcattccttccctggatgga
gacctcttccagtgggaccgggaccgtgagagcatggaaacagttccgtttacagttgaa
tcacttctcgaatcgtcttataagtttggagatgatgttgtcttggttggaggaaagtct
ctcactacatatggactcagtgcatatagtggaaaggtgaggtacatttgttcagctctg
ggttgtcgccagtgggataatgatgaaatggaacaagaagaagacatcttgcttctgcag
cgcacccagaaaactgtgagagccgttggacctcgcagtggcaatgagaagtggaatttc
agtgttggccactttgaacttcggtatattccagacatggaaactagagccggatttatt
gaaagcaccttaaagcccagtggaaacaaagaacagtctaaaattatttcagacgtggaa
gagcaggaagctgtcatgatggatacagtgataaaggtctccgttgcagattggaaagtt
atggcgtttaataagaagggaggacacctggagtgggaataccagttttgtactcccatt
gcatctgcctggttggttaaggatggcaaagtcattcccatcagtctttttgatgataca
agttacgcgcccaatgatggagttttagaagatgaagaagatattgtagaagctgcccgg
ggagccacagaaaacagtgtttacttgggaatgtacagaggccagctgtatctgcaatca
tcagtcagaatttcagaaaagtttcctacgagtcccaaggccttggaatctgtcagtagt
gaaaatgctattattcctttgccaaccatcaaatggaaacctctaattcattctccttct
agaactcctgtcttggtgggctctgatgaatttgacaaatgtcttagtaatgataagttt
tctcacgaagagtacagtaatggtgcgctttcaatcttgcagtatccttacgataatggt
tattatctgccatactataagagggaaagaaacaaacggagcacgcagatcacggtcaga
tttcttgacaacccgaattacaagaacatccgcaagaaggaccctgttcttctcttacac
tggtggaaagaaatagttggaaccatcgtgttttgtattgtagcaacaactttcattgta
cgcagactcttccatcctcatcctcacagacaaaggaaggaatctgaaactcagtgtcaa
actgaaaataaatatgatgctgtcagtggagaagctaatgacagtagctggaatgacata
aaaaattctggatacgtgtcacggtatctaacagactttgaaccaattcagtgcatgggc
cgtggggggtttggagttgtctttgaagctagaaacaaggttgatgactgcaattatgct
atcaagagaatccgtctccccaacagggaactggctcgggagaaggtaatgcgagaagtg
aaagccttagccaagcttgaacacccaggaattgtgagatatttcaatgcttggttggaa
gcgccaccagaaaagtggcaagaaaaaatggatgaaatttggctgaaagatgacagcaca
gactggccgctcagctctcctagtcccgtggacgcgccttctgttaaaatacgcagaatg
gatcctttctctacaaaggaatgtattgaaatcatagctccttcgccacacagcagcagg
tctttttcagttgggatttcttgcagccagaccagttcatccgagagccagttctctccg
ctggagttttccgggatggaccacggaaatgtgagcaagtcagcagatgcagtatgccaa
ctccaggacagctgccttacagactgcgagggggaggatggtaccatggatggtaatgat
gaagggcactcctttgaactttgtccttcggaagcttctccttacataaggtccagggag
cgaacctcctcgtctatagtatttgaagattctggctgtgataacgcgtccagcaaagag
gagcccagaatgaaccaaccccctgtgggcaaccattatgcgaataaactgtctgcactc
cggcattccggtagcaaatcttcggaacctactgtgtctgtttctccgtcaagaccaacc
actttaagtttagacctcactaaaagctcggtggggaaactccagcccagttcgcccaag
gtgtatctgtacatccagatgcagctgtgcagaaaggaaaacctcaaagactggctgaac
agccgctgcaccattgaggcgagagagaggagcgtatgtttgcacatctttctgcagatt
gcagaggcggtggagtttctgcacagcaaagggctcatgcacagggacctcaagccttcc
aacatattctttacaatggatgatgtggtcaaggttggggattttggactggtgacagca
atggaccaagacgaggaagatcagatggttctgaccccaatgccgggctacgccaggcac
acgggacaggtggggaccaagctgtatatgagcccggaacagattcatggcaacagctac
tctcataaagtggacatcttttctttgggcctcattctgtttgaattactatacccgttc
ggcactcaaatggaaagggtcaggatcctaactgatgtaagagatctcaaatttccacca
ctatttgctcaaaaatatcctcgtgagtatgccatggtgcaagacatgctgtccccatcc
cctactgaacggccagaagcggcgagcatcattgaaaacgcgatcttcgaggacttggag
tttccagaaaagacactcctcagacagaggtctcgctccatgagctcgcccggagcaaaa
cattcaagacactccagcagcccccacagccctttgcccagcaattag
DBGET
integrated database retrieval system
