Bos taurus (cow): 537380
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Entry
537380 CDS
T01008
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
bta
Bos taurus (cow)
Pathway
bta01524
Platinum drug resistance
bta04010
MAPK signaling pathway
bta04071
Sphingolipid signaling pathway
bta04141
Protein processing in endoplasmic reticulum
bta04210
Apoptosis
bta04530
Tight junction
bta04668
TNF signaling pathway
bta04714
Thermogenesis
bta04722
Neurotrophin signaling pathway
bta04932
Non-alcoholic fatty liver disease
bta04936
Alcoholic liver disease
bta05010
Alzheimer disease
bta05012
Parkinson disease
bta05014
Amyotrophic lateral sclerosis
bta05016
Huntington disease
bta05017
Spinocerebellar ataxia
bta05022
Pathways of neurodegeneration - multiple diseases
bta05208
Chemical carcinogenesis - reactive oxygen species
bta05417
Lipid and atherosclerosis
bta05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
537380 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
537380 (MAP3K5)
04668 TNF signaling pathway
537380 (MAP3K5)
04071 Sphingolipid signaling pathway
537380 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
537380 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
537380 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
537380 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
537380 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
537380 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
537380 (MAP3K5)
05012 Parkinson disease
537380 (MAP3K5)
05014 Amyotrophic lateral sclerosis
537380 (MAP3K5)
05016 Huntington disease
537380 (MAP3K5)
05017 Spinocerebellar ataxia
537380 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
537380 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
537380 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
537380 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
537380 (MAP3K5)
04932 Non-alcoholic fatty liver disease
537380 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
537380 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bta01001
]
537380 (MAP3K5)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
537380 (MAP3K5)
Protein kinases [BR:
bta01001
]
Serine/threonine kinases: STE group
STE11 family
537380 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
537380
NCBI-ProteinID:
NP_001137553
BGD-bta:
BT19383
Ensembl:
ENSBTAG00000009065
VGNC:
31198
UniProt:
F1MXH6
LinkDB
All DBs
Position
9:complement(74542301..74770948)
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSYRRGGAATAAEGEENQLPPPPPGSFWNVESAAAPGAGCP
SATSGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVVAESEALQCLREACETVGAALE
TLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTN
SDSLQSLKEIICQKNTMCTGNYTFIPYMITPHSKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQNEEQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGASWFKKAFESEPT
LQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGKNTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRDCANDLLMDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLVASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEGDHDERPSDQTVR
RPHAVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIDVPGLPGCHSSSPGTNTEDSELTDWLRENGADEDTIS
RFLAEDYSLMDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQA
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctccgtgccacccttcgccgagggcggc
agctaccggaggggaggagcggcgacggcggccgagggcgaggagaaccagctgccaccg
ccgccaccgggcagcttctggaacgtggaaagtgccgccgctcccggcgccgggtgtccc
agtgccacctccgggagcagcgccacccggtgccggggcaactctgggggcggaggcggc
cgacggaccacggtggcctatgtcatcaacgaggcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagtgcctgcgggaggcgtgcgagacggtgggcgccgccctggag
accctgcattttgggaaactggactttggggaaactgcggtgctggaccgattttacaat
gcagatatcgccgtggtggagatgagtgatgccttccgacaaccatccttattttaccac
cttggagtgagagaaagtttcagcatggccaacaacatcatcctctactgtgatactaat
tcagactctctgcagtcgctgaaggagatcatttgccagaagaatactatgtgcactgga
aactacacatttatcccttacatgataacgccgcacagcaaggtctactgctgtgacagc
agcttcatgaagggcttgactgagctcatgcagccgaactttgagctgcttctgggaccc
atctgcttacctctcgtggatcgtttcattcagcttttgaaggtggcacaagcaagttcc
agccagtatttccgggagtctatactcaacgatatcaggaaagctcgtaacttatatact
ggcaaagaattggcagctgaattggcaagaattcgacagcgagtggataatattgaagtc
ttgacagcagatattgtcataaatctgttactttcatatagagatatccaggactatgat
tctattgtgaagctggtagagactttagaaaagcttccaacgtttgatttggcctcccat
caccatgtgaagtttcattatgcctttgcactgaataggagaaacctccctggagataga
gcaaaagctcttgacattatgattcccctggtgcaaaatgaagagcaggttgcttcagat
atgtattgcctcgttggtcgaatctacaaagatatgtttttggactctaatttcatggac
actgaaagtagagaccatggagcttcttggttcaaaaaggcatttgaatcagagccaaca
ctacagtcaggaattaattatgcggtcctcctcctggcatctgggcaccagtttgaatct
tcctttgagctccgaaaagttggggtgaagctaagtagtcttcttggtaaaaagggaaac
ttggaaaaactccagagctactgggaagttggatttttcctgggggccagtgtcctggcc
aatgaccacttgagagtcattcaagcatctgaaaagctttttaaactgaagacacctgca
tggtacctcaagtctatcgtagagacaattttgatatataagcattttgtgaaactgact
tcggaacagcctgtggccaaacaggaacttgtggacttctggatggatttcctggtcgag
gccacaaagacagatgtcactgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcgtatttgtctatcaacaatgaagttgaggagaagacaatatctatt
tggcacgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggtgtgagtatttctaaatttgaagaacgatgctgttttctgtacgtgcttcac
aattctgacgatttccaaatctacttctgtacagaacttcactgtaaaaagttttttgaa
atggtgaacaccattactgaagagaaggggaaaaacacagaggaaggagattgtgaaggt
gactccctggagtatgactatgaatacgatgaaaatggtgacagagtcgttttaggaaaa
ggcacttatgggatagtttatgcaggtcgagatctgagcaaccaagtcagaatcgccatt
aaggaaatcccagagagagacagcagatactcccagcccctgcatgaagaaatagccttg
cataagcatctgaagcacaaaaatattgtccagtatctgggctctttcagtgaaaacggt
ttcattaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgttcc
aaatggggcccactgaaagacaatgagcaaacaattggcttttatacaaagcaaatactg
gaaggattaaaatacctccatgataatcagatagttcaccgggatataaagggtgacaat
gtgttgattaatacctacagcggtgttctcaagatttctgatttcggaacatcaaagagg
cttgctggcataaatccatgtactgaaacttttactggtaccctccagtatatggcacca
gaaataatagataaaggaccaagaggctatggaaaggcagcagacatttggtctctgggc
tgcacgatcattgaaatggccactggaaaaccacccttttatgaactgggggaaccacaa
gcagctatgttcaaggtggggatgtttaaagtccacccagagatcccagagtccatgtca
gcagaggccaaggcgttcatattgaagtgtttcgaaccagaccctgacaagagagactgt
gctaacgacttgcttatggatgagttcttaaaagtttcaagcaaaaagaaaaagacacaa
cctaagctttcagctctttcagctggatcgaatgagtacctcaggagtatctccttgcca
gtgccagtcctggtggaggacacgagcagcagcagtgagtacggctcagtttcccctgac
acagagttgaaggtggaccccttctctttcaaaacaagagccaagtcctgtggagaaaag
gatgtcaaaggcatccggacgctgtttctgggcatccctgatgaaaattttgaagaccac
agtgctccaccttctccagaagaaaaagattccggattctttatgctgaggaaggacagt
gagagacgggccacgcttcacaggattctgacggaagaccaagacaaagttgtgagaaac
ttaatggaatccttggctcagggggctgaagaacctaaactgaaatgggaacacatcaca
actctggtcgcaagcctcagagaatttgtgaggtccacggaccggaagatcatagccacc
accctgtccaagctgaagctggagctggacttcgacagccacgggatcagtcaggtccag
gtggtgctctttggtttccaagatgctgtcaataaagttcttcggaatcataacatcaag
ccacactggatgtttgccttagacagtatcatccgaaaggcggtacagacagctattacc
attctggttccagaactgaggccgcatttcagccttgcatctgagagtgatactgccgat
caagaagacttggatgcagaaggtgaccatgacgaacggccttcagatcaaactgtccga
agacctcatgccgtccttgaagacgcggtggccacctcaggggtgagcacgctcagttct
actgtatcccatgactcccagagtgctcaccgatcactgaatgtacagcttggaaggatg
aaaatagaaacaaatagattactggaagaattggttcagaaagagaaagaattacaagca
ctccttcatcaagctattgaagagaaagaccaagaaattaaacacctgaagcttaagtcc
caaccaatagatgttcctgggttgcctgggtgtcactccagttctcctggcacaaacact
gaagattcggaacttactgactggctgagagagaacggagctgatgaagacactataagt
cggtttttggctgaggattattcattaatggatgttctctactatgttacacgtgatgat
ttaaaatgcctgagactaaggggcgggatgctgtgcacactgtggaaagccatcactgac
ttccgagacaaacaggcttga
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