Bos taurus (cow): 787450
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Entry
787450 CDS
T01008
Symbol
ALOX12E
Name
(RefSeq) arachidonate 12-lipoxygenase, epidermal-type
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
bta
Bos taurus (cow)
Pathway
bta00590
Arachidonic acid metabolism
bta01100
Metabolic pathways
bta01523
Antifolate resistance
bta04726
Serotonergic synapse
bta04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
787450 (ALOX12E)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
787450 (ALOX12E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
787450 (ALOX12E)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
787450 (ALOX12E)
Enzymes [BR:
bta01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
787450 (ALOX12E)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
787450
NCBI-ProteinID:
NP_001077001
BGD-bta:
BT17869
Ensembl:
ENSBTAG00000031933
UniProt:
A4FV70
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Position
19:26726714..26736424
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AA seq
633 aa
AA seq
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MGKYRIRVATGDSLLAGSSNLVQLWLVGEHGEKDLGKILRPIRIREVQLEVEVSLYLGRL
LLVKLRKHKSLVGFDWFCKWIAVQGPGTQGEAFFPCYRWVQGNEIICLPEGTARTVRDDP
QNQFKKHREKELEERRKVYRWGFWKEGLILPIAGNTQWDLPRNERFLEDKDLDFSLSLAK
VLKDLALKGSLDLTNSVRRLEDFNKVFPQGKTPLAERVRNCWKDDALFGYQFLNGANPML
LRRSTSLPSRLVLPPEMEDLKTQLEKELQTGSLFEADFSLLDGVKPNVIIFKQQYVAAPL
VMLKLQPDGRLLPMVIQLQPPRNGCPPPVLFLPSDPPMAWLLAKTWVRSSDFQLHQLQSH
LLRGHLIAEVISVATMRSLPSLHPIYKVVSTGSGGHVDILQRATAGLTYRSFCPPDDLAD
RGLLDVKSSLYGQDALRLWGVISRYVEKMVSLFYKSDGAVKDDPELQAWCREITETGLQG
AQDRGFPISLESRAQLCHFITMCIFTCTGQHASTHQGQLDWYSWIPNGPCTMQKPPPISK
DVTEKDIVDSLPSLHQARTQKTFIKFLGRRQPVMVALGQHKENYFSDPGPQAVLKQFQEE
LAALDKEIEVRNAGLDLPYEYLRPSMVENSVTI
NT seq
1902 nt
NT seq
+upstream
nt +downstream
nt
atgggcaaatacaggattcgcgtcgccaccggagactcgctcttggctggctccagcaac
ctagtgcagctgtggctggtgggcgagcacggggagaaggacctggggaagatactgcgg
ccgatacggatcagggaggtgcagctcgaggtcgaagtctccctatacctggggcgcctc
ctgctggtgaagctgcgcaagcacaaaagcctggtgggtttcgactggttctgcaagtgg
atcgcggtccagggtcccggcacccaaggcgaggcctttttcccctgctaccgctgggtg
cagggcaacgagatcatctgcttgcccgagggcaccgcccggaccgtgagggatgatccc
cagaaccagtttaagaaacatcgggagaaagagcttgaggaaagaaggaaggtgtaccga
tggggtttctggaaagagggattaatcctgcctatagcagggaatacacaatgggatctt
cccagaaacgagagatttcttgaagataaggatttagacttcagtctctctctggcaaaa
gtgttgaaggacttggccttaaaggggtcattagatctcacaaattctgtaagaagactg
gaagacttcaataaagtattcccgcaaggaaaaactcctctggctgagcgggtccgcaat
tgctggaaggatgatgccctatttgggtaccagttcctcaacggggcaaaccctatgctc
ctgagacgctccacgagtctcccgtcacggttggtgctgcctccggaaatggaagacttg
aagacacagctggagaaagaactccagactggatctctctttgaagctgacttctccctg
ctggatggggtcaagcctaatgtcatcatttttaagcaacagtatgtagcagcccctctg
gtcatgctgaagctccagcccgatggaagacttttacctatggtcatccagctccagcca
cctcggaatggatgccccccacctgtgttgttcctgccttcggatccccccatggcctgg
ctccttgccaagacctgggtccggagctctgatttccagctccaccagctacagtcacac
ctgctgaggggccacctgatagccgaggttatttctgtggccaccatgaggagcctgccc
agcctgcatcctatctacaaggtggtgagcactgggagtggcggccatgtagacattctc
cagagagccacagctggtctgacctatcgctccttctgccctcctgatgacctggcagac
cgtgggctcctggatgtgaagtcttctctctatggccaagatgcgctcaggctctgggga
gtcatcagccggtacgtagagaagatggtcagtcttttctacaagagtgatggagctgtg
aaggatgatccagaactgcaggcctggtgtagagagatcactgagactggactgcagggg
gctcaggaccgggggttccctatctccttagagtcccgagctcagctctgccacttcatc
accatgtgcatcttcacgtgcactggtcagcatgcttccacccaccagggccagctggac
tggtactcctggatcccgaatggtccatgcaccatgcagaagcctccgcccatctccaag
gatgtgacagagaaggatatagtagactcactgcctagtctgcaccaggcccgaacacag
aagacattcataaaattccttggccgacgccagcctgtcatggtggccttggggcagcac
aaagaaaactatttctctgaccctggacctcaagctgtgctgaagcaattccaggaggag
ttggctgccctggacaaggagattgaggtccgaaatgcaggcctggacctgccctatgag
tatcttcgacccagcatggtagagaacagtgtgaccatttga
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