Budorcas taxicolor (takin): 128046764 Help Entry 128046764         CDS       T08909                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism btax  Budorcas taxicolor (takin) Pathway btax00230   Purine metabolism btax01100   Metabolic pathways btax01522   Endocrine resistance btax04015   Rap1 signaling pathway btax04020   Calcium signaling pathway btax04022   cGMP-PKG signaling pathway btax04024   cAMP signaling pathway btax04062   Chemokine signaling pathway btax04072   Phospholipase D signaling pathway btax04081   Hormone signaling btax04082   Neuroactive ligand signaling btax04114   Oocyte meiosis btax04211   Longevity regulating pathway btax04213   Longevity regulating pathway - multiple species btax04261   Adrenergic signaling in cardiomyocytes btax04270   Vascular smooth muscle contraction btax04371   Apelin signaling pathway btax04540   Gap junction btax04611   Platelet activation btax04713   Circadian entrainment btax04714   Thermogenesis btax04720   Long-term potentiation btax04723   Retrograde endocannabinoid signaling btax04724   Glutamatergic synapse btax04725   Cholinergic synapse btax04727   GABAergic synapse btax04750   Inflammatory mediator regulation of TRP channels btax04911   Insulin secretion btax04912   GnRH signaling pathway btax04913   Ovarian steroidogenesis btax04914   Progesterone-mediated oocyte maturation btax04915   Estrogen signaling pathway btax04916   Melanogenesis btax04918   Thyroid hormone synthesis btax04921   Oxytocin signaling pathway btax04923   Regulation of lipolysis in adipocytes btax04925   Aldosterone synthesis and secretion btax04926   Relaxin signaling pathway btax04927   Cortisol synthesis and secretion btax04928   Parathyroid hormone synthesis, secretion and action btax04934   Cushing syndrome btax04935   Growth hormone synthesis, secretion and action btax04970   Salivary secretion btax04971   Gastric acid secretion btax04972   Pancreatic secretion btax04976   Bile secretion btax05032   Morphine addiction btax05142   Chagas disease btax05146   Amoebiasis btax05163   Human cytomegalovirus infection btax05166   Human T-cell leukemia virus 1 infection btax05200   Pathways in cancer btax05207   Chemical carcinogenesis - receptor activation btax05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:btax00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     128046764 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     128046764 (ADCY1)    04371 Apelin signaling pathway     128046764 (ADCY1)    04020 Calcium signaling pathway     128046764 (ADCY1)    04072 Phospholipase D signaling pathway     128046764 (ADCY1)    04024 cAMP signaling pathway     128046764 (ADCY1)    04022 cGMP-PKG signaling pathway     128046764 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     128046764 (ADCY1)    04081 Hormone signaling     128046764 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     128046764 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     128046764 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     128046764 (ADCY1)    04062 Chemokine signaling pathway     128046764 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     128046764 (ADCY1)    04923 Regulation of lipolysis in adipocytes     128046764 (ADCY1)    04912 GnRH signaling pathway     128046764 (ADCY1)    04913 Ovarian steroidogenesis     128046764 (ADCY1)    04915 Estrogen signaling pathway     128046764 (ADCY1)    04914 Progesterone-mediated oocyte maturation     128046764 (ADCY1)    04921 Oxytocin signaling pathway     128046764 (ADCY1)    04926 Relaxin signaling pathway     128046764 (ADCY1)    04935 Growth hormone synthesis, secretion and action     128046764 (ADCY1)    04918 Thyroid hormone synthesis     128046764 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     128046764 (ADCY1)    04916 Melanogenesis     128046764 (ADCY1)    04925 Aldosterone synthesis and secretion     128046764 (ADCY1)    04927 Cortisol synthesis and secretion     128046764 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     128046764 (ADCY1)    04270 Vascular smooth muscle contraction     128046764 (ADCY1)   09154 Digestive system    04970 Salivary secretion     128046764 (ADCY1)    04971 Gastric acid secretion     128046764 (ADCY1)    04972 Pancreatic secretion     128046764 (ADCY1)    04976 Bile secretion     128046764 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     128046764 (ADCY1)    04727 GABAergic synapse     128046764 (ADCY1)    04725 Cholinergic synapse     128046764 (ADCY1)    04720 Long-term potentiation     128046764 (ADCY1)    04723 Retrograde endocannabinoid signaling     128046764 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     128046764 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     128046764 (ADCY1)    04213 Longevity regulating pathway - multiple species     128046764 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     128046764 (ADCY1)    04714 Thermogenesis     128046764 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     128046764 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     128046764 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     128046764 (ADCY1)    05163 Human cytomegalovirus infection     128046764 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     128046764 (ADCY1)    05142 Chagas disease     128046764 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     128046764 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     128046764 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     128046764 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     128046764 (ADCY1) Enzymes [BR:btax01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      128046764 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF7246 Motif Other DBs NCBI-GeneID:  128046764 NCBI-ProteinID:  XP_052494919 LinkDB All DBs Position 4:complement(78074749..78173480) Genome browser AA seq 1134 aa AA seqDB search MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQ AATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLP VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNMYGVFVRILAERA QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA LRTASEKLRNRSSFSTNVVQATPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERE RKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPV LPAPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGA GAISGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRIL FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIE MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR IQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMCPY GRAGLQTRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA NT seq 3405 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggcggcggaggcggaggcggcgccggcgagtct gggggcgccgagcgggcggcggggccgggcggccggcgcgggctgcgggcgtgcgatgag gagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcag gcggcgacgctgaaggcgctggccgtgctcagcctgctggcgggcgcgctggccctggcc gagctgctgggcgcgccggggcccgcgcccggcctggccaagggctcgcaccccgtgcac tgcgtgctcttcctggcgctgctcgtggtcaccaacgtccgctcgctgcaggtgccccag ctgcagcaggtcggccagctcgcgctgctcttcagcctcaccttcgctctgctgtgctgt cccttcgcgctcggcggccccgccggtgcccacgccggggcggcagcggtgccggcgaca gccgatcagggagtctggcagctccttttggtcaccttcgtgtcctatgccctgctgccc gtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacctgctggtc acagctacgttggtccccgccaagcgcccacgtctctggagaacgctgggtgccaacgct ctgctcttccttggtgtgaacatgtatggtgtcttcgtgaggatcctggctgagcgcgcc cagaggaaggccttcctgcaggcccggaactgcattgaggaccggctgaggctggaggac gagaatgagaagcaggagcggctgctcatgagcctcctgcctcggaatgttgccatggag atgaaggaggacttcctgaagccccctgagaggattttccacaagatttatatccagcgg catgacaatgtgagcatcctctttgcagacatcgtgggcttcacgggcttggcgtcacag tgcacggcccaagagctggtgaaactcctcaacgagctcttcgggaagtttgacgagctg gccacggagaaccactgccgccgcatcaagatcctgggagattgctactactgcgtgtct ggcctcactcagcccaagactgaccacgcccactgctgtgtggagatgggcctggacatg atcgacaccatcacgtccgtggctgaggccactgaggtggacttgaacatgcgtgtgggg ctgcacaccggcagggtcctctgtggggtcctgggcctgcgtaagtggcagtatgatgtg tggtccaacgatgtgaccctggccaacgtcatggaggccgccggcctgcctgggaaggtt cacatcacaaagaccaccctggcgtgcctgaacggtgactatgaggtggagccgggacac ggacatgagaggaacagttttctgaaaacgcataacattgagaccttttttattgtgccc tcacatcggcgaaagatatttccagggctgattctctcagacataaaaccggccaagagg atgaagttcaagactgtgtgctacctgctggtgcagctcatgcattgccggaagatgttc aaggccgagatccctttctccaacgtcatgacctgtgaggacgacgacaagcggagggca ttgagaacagcctcggaaaaactcagaaaccgctcgtctttctctacaaacgttgtccaa gccacccccggcacacgtgtcaacaggtacatcggccgcctcctggaagcccgccagatg gagctggagatggcagacctgaacttcttcaccctgaagtacaagcaagctgagcgagag cgaaagtaccaccagcttcaggacgagtatttcaccagcgccgtggttctggctctcatt ctggccgccttattcggccttgtctaccttctaataatcccacagagtgtggctgtcctg ctcctgctggtgttctgcatctgcttcctggtggcctgtgtcctgtacctacacatcacc cgggtccagtgttttccagggtgcctgaccatccagatccgcaccgtcttgtgcatcttc atcgtggtcttaatctactctgtggcccaaggctgtgtggtgggctgcctgccttggtcc tggagctccagtcccaatgggtccctggtggtcctgtcttccgggggccgggacccagtg ctgcctgccccgccctgcgagtctgcgccccacgccctgctgtgcggcctcgtgggcacc ctcccgctggccatattcctgcgggtctcctccttgccaaaaatgatcctgctcgccgtg cttaccacctcctacatcctcgtcctggagctcagcgggtacacgaaggccatgggggcc ggtgccatctcagggcgcagcttcgagccgatcatggccatcctgctattctcgtgcacg ctggccctgcacgcccggcaggtggatgtcaagctgcggctggactacctctgggcggcc caggcagaggaggagcgggatgacatggagaaagtgaagctggataacaagaggattctc ttcaacctcctgccagcccacgttgcccagcacttcctaatgtccaaccctcgcaacatg gacctgtattaccagtcatactcgcaggtgggggtcatgtttgcatccatccccaacttc aatgacttctacattgagctggatggcaacaacatgggggtggagtgtctgcgccttctg aacgagatcatcgccgactttgatgagctcatggacaaagacttttacaaagacctagag aagatcaagaccatcgggagcacgtacatggctgctgtggggctggcgcccactgctggg accaaggctaagaagtgcatctcctcccacctcagcacgttggcagattttgccatcgag atgtttgatgtcctggatgagatcaactaccagtcttataacgactttgtgctccgtgtt ggcatcaacgttggccctgtggtggctggagtgatcggggctcgcaggccacagtatgac atttggggaaacacggtcaatgtggccagtcggatggacagtactggcgtccagggcagg atccaggtcacagaggaagttcaccggctgctgcggcggggttcctaccgcttcgtgtgc cgaggcaaagtcagtgtcaagggcaagggcgagatgctgacatacttcctggaaggcagg accgatggaaatggctcccaaaccaggtccctgaactcagagcggaaaatgtgtccttac ggaagagctggcctccagaccagactggccgcgggtcatcctccagtgccccctgcagcc ggcctcccggttggagctgggccaggggctctgcagggctcggggcttgccccaggcccc ccaggccaacacctgccccctggagcctctgggaaggaggcttag

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