Budorcas taxicolor (takin): 128050313 Help Entry 128050313         CDS       T08909                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism btax  Budorcas taxicolor (takin) Pathway btax04010   MAPK signaling pathway btax04014   Ras signaling pathway btax04015   Rap1 signaling pathway btax04022   cGMP-PKG signaling pathway btax04066   HIF-1 signaling pathway btax04068   FoxO signaling pathway btax04072   Phospholipase D signaling pathway btax04081   Hormone signaling btax04150   mTOR signaling pathway btax04151   PI3K-Akt signaling pathway btax04152   AMPK signaling pathway btax04211   Longevity regulating pathway btax04213   Longevity regulating pathway - multiple species btax04520   Adherens junction btax04910   Insulin signaling pathway btax04913   Ovarian steroidogenesis btax04923   Regulation of lipolysis in adipocytes btax04930   Type II diabetes mellitus btax04931   Insulin resistance btax04932   Non-alcoholic fatty liver disease btax04960   Aldosterone-regulated sodium reabsorption btax05010   Alzheimer disease btax05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:btax00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     128050313 (INSR)    04014 Ras signaling pathway     128050313 (INSR)    04015 Rap1 signaling pathway     128050313 (INSR)    04066 HIF-1 signaling pathway     128050313 (INSR)    04068 FoxO signaling pathway     128050313 (INSR)    04072 Phospholipase D signaling pathway     128050313 (INSR)    04022 cGMP-PKG signaling pathway     128050313 (INSR)    04151 PI3K-Akt signaling pathway     128050313 (INSR)    04152 AMPK signaling pathway     128050313 (INSR)    04150 mTOR signaling pathway     128050313 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     128050313 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     128050313 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     128050313 (INSR)    04923 Regulation of lipolysis in adipocytes     128050313 (INSR)    04913 Ovarian steroidogenesis     128050313 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     128050313 (INSR)   09149 Aging    04211 Longevity regulating pathway     128050313 (INSR)    04213 Longevity regulating pathway - multiple species     128050313 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     128050313 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     128050313 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     128050313 (INSR)    04932 Non-alcoholic fatty liver disease     128050313 (INSR)    04931 Insulin resistance     128050313 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:btax01001]     128050313 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:btax04090]     128050313 (INSR) Enzymes [BR:btax01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      128050313 (INSR) Protein kinases [BR:btax01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    128050313 (INSR) CD molecules [BR:btax04090]  Proteins   128050313 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  128050313 NCBI-ProteinID:  XP_052498480 LinkDB All DBs Position 7:complement(16087979..16235585) Genome browser AA seq 1382 aa AA seqDB search MGAGGWRGAAAVLLMVVVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCVPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWGKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPSRKRRALGDVGNVTAAVPTVLGF PNSSSTSTPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV SRRHYALERGCRLRGLLPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSICLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMESVPLDRSSHAQREEAGGRDGGSALGLKRNYDEHIPYSHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggctggaggggggcggcagccgtgctgctgatggtggtcgtcgccgcg ctgctggtgggcgccgcgggccacctgtaccctggagaagtgtgccccggtatggatatc cgaaataatctcacccggctgcatgagctggccaactgctcggtcattgaaggacatttg cagattctgttgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag gacttgttccccaacctcacggtcatccgaggctcgcgcctcttctttaattatgcactg gtcatctttgagatggttcacctgaaggagcttggcctctacaacctgatgaacatcacc cgggggtctgtccgcatcgagaagaacaatgaactctgctacctggccaccatcgactgg tctcgcatcctggattccgtggaggataattacatcgtgctgaacaaagacgacaatgag gagtgtggggacatttgtccaggcaccgccaagggcaagaccaactgccctgccactgtc atcaatgggcaatttgtggagcggtgctggacacacagccactgccagaaagtgtgtccg actatctgtaagtcacatggctgcacctctgagggtctctgctgccacagcgagtgcttg ggcaactgctcagagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gacggcaggtgcgtggagacctgcccgcccccttactaccacttccaagactggcgctgc gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcaaggc tgccaccagtatgtcattcacaacaacaagtgcgtccccgagtgcccctctggctacacg atgaattctagcaacttgatgtgtaccccttgcctgggcccctgtcccaaggtatgccac ctcctggaaggtgagaagaccatcgattcagtgacatctgcccaggagctccgaggctgc accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag ctagaggccaaccttggactcattgaagaaatttcaggatatctgaaaatccgccggtcc tatgccctggtatcactttccttcttccggaagttacgtctgattcgaggggagaccttg gaaattgggaactactctttctacgccttggacaaccagaacctaaggcagctatgggac tggggcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa ctgtgcctgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag agaaatgacattgctctaaagaccaatggggaccaggcatcctgtgaaaatgaattactt aaattttcttacattcggacatcttatgacaagatcttgctgaaatgggagccgtattgg cctcctgacttccgagacctcctggggttcatgttgttctacaaagaggccccttaccag aatgtgacagaattcgatgggcaggatgcgtgcggctccaacagctggacagtggtggat attgacccgcctacgaggtccaacgaccccaagtcacagaaccatcctgggtggctgatg cgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtcaccttttct gatgaacgccgtacatacggagccaagagtgacatcatctatgtccagacagacgccact aatccttccgtccccctggatcccatctcagtttctaattcctcgtcccagattattctg aagtggaagcctccctccgaccccaacggcaatatcacacactacttggtgttctgggag aggcaggcggaagacagtgagctgtatgaactggattattgcctcaaagggttgaagctg ccctcccggacctggtctccaccgttcgagtcggaggggtcccagaagcacaaccagagt gagtatgaggagtctgctggcgaatgctgctcctgcccgaagaccgactctcagatcctc aaggagctggaggagtcctcgttcaggaaaacgtttgaagattacctgcacaacgtggtt ttcatccccagaaagtcatcttcaggccctgttgccgaggacgctaggccttcgaggaaa cgcagagcccttggtgacgtggggaatgtgacagcagccgtgcccactgttctggggttc cccaatagctcctccaccagcacacccacgagctcagaggagcacagacccttcgagaaa gtggtgaacaaggagtcgctggtcatctccggcctgcgtcactttactgggtatcgcatc gagcttcaggcttgcaaccaagattcccccgaggagaggtgtagcgtggctgcctatgtc agcgccaggaccatgcctgaagccaaggcagatgatattgtcggccccgtgacccatgaa atcttcgagaacaacgtcgttcacttgatgtggcaggagcccaaggaacccaacggtctg attgtgctgtatgaagtgagttaccgacgatacggcgaggaggagctgcacctctgcgtc tcccgccggcattatgctctggagcgcggctgccggctgcgcgggctgctgcctgggaat tacagcgtgcgagttcgggccacctccctggcaggcaatgggtcttggacggaagccacc tacttctacgtgacagactatttagacgtgccatcaaatattgcaaaaatcatcatcggt cccctcatctttgtctttctcttcagtgttgtgattggaagtatttgtctattcctgaga aagaggcagccagatgggccactgggaccactgtatgcttcttcaaacccagagtacctc agtgccagcgatgtgttcccatgctctgtgtatgtgccggacgagtgggaggtgcctcga gagaagatcacgctcctgcgagaactggggcaaggctccttcggcatggtgtacgagggc aacgccagggacattgtcaagggtgaggcggagacccgcgtggcagtgaagacggtcaat gagtcggccagcctgcgagagcggatcgagtttctcaacgaggcttcggtcatgaagggc ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctg gtggtgatggagttgatggctcacggagacctgaagagttacctccgttccctgcggcct gaggctgagaataaccccggccgccctccccctaccctgcaagaaatgattcagatggcg gcagagatcgccgatgggatggcatacctgaacgctaagaagttcgtgcaccgggatctt gcagcccggaactgcatggttgcccacgactttaccgtcaaaattggagacttcggaatg acaagagacatctatgaaacggattactaccggaaagggggcaaaggtctgctccccgtg cggtggatggcacctgaatccctcaaggacggagtcttcaccacctcttcggacatgtgg tcttttggtgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggtcta tcaaatgagcaggtgctgaaatttgtcatggatggagggtacctggatcaacctgacaat tgtccagagagagtcaccgacctgatgcggatgtgctggcagttcaaccctaagatgcgt ccgaccttcctggagatcgtggacctgctcaaggatgacctgcaccccagctttcccgaa gtgtccttcttccacagcgaggagaacaaggcgcccgagagcgaggagctggaaatggag tttgaggacatggagagcgtgcccctggaccggtcctcgcacgcgcagagagaggaggcc gggggccgggacggagggtcggcgctggggctaaagcgaaactatgacgagcacatcccc tacagccacatgaacgggggcaagaaaaacggacggattctgactttgccccggtcaaat ccttcctaa

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