Budorcas taxicolor (takin): 128059256 Help Entry 128059256         CDS       T08909                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism btax  Budorcas taxicolor (takin) Pathway btax00230   Purine metabolism btax01100   Metabolic pathways btax01522   Endocrine resistance btax04015   Rap1 signaling pathway btax04020   Calcium signaling pathway btax04022   cGMP-PKG signaling pathway btax04024   cAMP signaling pathway btax04062   Chemokine signaling pathway btax04072   Phospholipase D signaling pathway btax04081   Hormone signaling btax04082   Neuroactive ligand signaling btax04114   Oocyte meiosis btax04211   Longevity regulating pathway btax04213   Longevity regulating pathway - multiple species btax04261   Adrenergic signaling in cardiomyocytes btax04270   Vascular smooth muscle contraction btax04371   Apelin signaling pathway btax04540   Gap junction btax04611   Platelet activation btax04713   Circadian entrainment btax04714   Thermogenesis btax04720   Long-term potentiation btax04723   Retrograde endocannabinoid signaling btax04724   Glutamatergic synapse btax04725   Cholinergic synapse btax04727   GABAergic synapse btax04742   Taste transduction btax04750   Inflammatory mediator regulation of TRP channels btax04911   Insulin secretion btax04912   GnRH signaling pathway btax04913   Ovarian steroidogenesis btax04914   Progesterone-mediated oocyte maturation btax04915   Estrogen signaling pathway btax04916   Melanogenesis btax04918   Thyroid hormone synthesis btax04921   Oxytocin signaling pathway btax04923   Regulation of lipolysis in adipocytes btax04925   Aldosterone synthesis and secretion btax04926   Relaxin signaling pathway btax04927   Cortisol synthesis and secretion btax04928   Parathyroid hormone synthesis, secretion and action btax04934   Cushing syndrome btax04935   Growth hormone synthesis, secretion and action btax04970   Salivary secretion btax04971   Gastric acid secretion btax04972   Pancreatic secretion btax04976   Bile secretion btax05032   Morphine addiction btax05163   Human cytomegalovirus infection btax05166   Human T-cell leukemia virus 1 infection btax05200   Pathways in cancer btax05207   Chemical carcinogenesis - receptor activation btax05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:btax00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     128059256 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     128059256 (ADCY8)    04371 Apelin signaling pathway     128059256 (ADCY8)    04020 Calcium signaling pathway     128059256 (ADCY8)    04072 Phospholipase D signaling pathway     128059256 (ADCY8)    04024 cAMP signaling pathway     128059256 (ADCY8)    04022 cGMP-PKG signaling pathway     128059256 (ADCY8)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     128059256 (ADCY8)    04081 Hormone signaling     128059256 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     128059256 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     128059256 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     128059256 (ADCY8)    04062 Chemokine signaling pathway     128059256 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     128059256 (ADCY8)    04923 Regulation of lipolysis in adipocytes     128059256 (ADCY8)    04912 GnRH signaling pathway     128059256 (ADCY8)    04913 Ovarian steroidogenesis     128059256 (ADCY8)    04915 Estrogen signaling pathway     128059256 (ADCY8)    04914 Progesterone-mediated oocyte maturation     128059256 (ADCY8)    04921 Oxytocin signaling pathway     128059256 (ADCY8)    04926 Relaxin signaling pathway     128059256 (ADCY8)    04935 Growth hormone synthesis, secretion and action     128059256 (ADCY8)    04918 Thyroid hormone synthesis     128059256 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     128059256 (ADCY8)    04916 Melanogenesis     128059256 (ADCY8)    04925 Aldosterone synthesis and secretion     128059256 (ADCY8)    04927 Cortisol synthesis and secretion     128059256 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     128059256 (ADCY8)    04270 Vascular smooth muscle contraction     128059256 (ADCY8)   09154 Digestive system    04970 Salivary secretion     128059256 (ADCY8)    04971 Gastric acid secretion     128059256 (ADCY8)    04972 Pancreatic secretion     128059256 (ADCY8)    04976 Bile secretion     128059256 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     128059256 (ADCY8)    04727 GABAergic synapse     128059256 (ADCY8)    04725 Cholinergic synapse     128059256 (ADCY8)    04720 Long-term potentiation     128059256 (ADCY8)    04723 Retrograde endocannabinoid signaling     128059256 (ADCY8)   09157 Sensory system    04742 Taste transduction     128059256 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     128059256 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     128059256 (ADCY8)    04213 Longevity regulating pathway - multiple species     128059256 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     128059256 (ADCY8)    04714 Thermogenesis     128059256 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     128059256 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     128059256 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     128059256 (ADCY8)    05163 Human cytomegalovirus infection     128059256 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     128059256 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     128059256 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     128059256 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     128059256 (ADCY8) Enzymes [BR:btax01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      128059256 (ADCY8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  128059256 NCBI-ProteinID:  XP_052507611 LinkDB All DBs Position 14:23297303..23529455 Genome browser AA seq 1250 aa AA seqDB search MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGN GSSSKASDPGGGGPNHHHASQLSGDSALPLYALGPGERAHGTGGPKVFPERSGSGSGSGS GGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKS EVVMNVLDVLTKLTLLVLHLSLAAAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTY LQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSL MQVVLQAVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARL RLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVK GFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHC CVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLE SGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDI VKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQ SGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFI VLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINET YLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGV LAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEAS LLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVAR HFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDEL LGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHS FNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILK DQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQ SLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAPAEGADKSELP NT seq 3753 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgcctgagcggcagcgaggaactctacaccatccacccg acgcccccggccggcgacggcgggagcggctcccggccgcagcggctgctgtggcagacg gcggtgcggcacatcaccgagcagcgcttcatccacgggcaccgcggcggcggcgggaac ggaagctccagcaaagcctcggaccccggaggcggcggccccaaccaccaccacgcgtcg cagctgtctggcgactcggcgctgcccctctacgcgctgggccctggggagcgagcgcac ggcaccggcggccccaaagtcttcccggaacgcagcgggagcggcagcggcagcggcagc ggcggcgggggcgacctgggcttcctgcacctcgactgcgccccgagcaactcggatttc ttcctcagtgggggctacagctaccgaggggtcattttccccaccctgcgcaactccttt aagtcccgggatctggagcgcctctaccagcgctatttcctgggccagaggcgcaaatcg gaggtggtgatgaacgtgctggacgtgctgaccaaactcaccctcctggttctccacttg agcctggccgcggcccccatggacccgctcaagggcatcctgctgggcttcttcaccggc atagaggtggtgatctgcgccctggtggtggtcaggaaggacaccacctcgcacacatac ctgcagtacagcggtgtggtcacttgggtagccatgaccacccagatcttagcagcaggg ctcggctatgggctcctgggagacggcatcggctacgtgctcttcaccctttttgccacc tacagcatgctgccgctgccgctcacctgggccatcctggccggcctaggcacctctttg atgcaggtggtcctccaagcggtcatccccaggctggcggtcatttccatcaatcaggtt gtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagttacctg tcagaccgggcccagcgccaagccttcctggagacacggaggtgtgtggaggccaggctg cgcctggagacggaaaaccaaagacaggagcgacttgtgctgtccgtgcttcctcgtttt gttgtcctggagatgatcaacgatatgaccaacgtggaagacgagcacctgcagcatcag ttccaccggatctacatccatcgctatgagaatgtcagtattctttttgcagatgttaaa ggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctcaacgag ctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatcctg ggggactgctactactgcgtttcaggactgcctgagccccgccaggaccacgcccactgc tgtgttgaaatgggcctcagcatgatcaaaaccatcaggtatgtgcgatcaaggacgaag cacgatgttgacatgcggattggaatccactcgggctcggtgctgtgtggcgtgttgggt cttcggaagtggcagtttgatgtctggtcttgggatgtggacattgcgaacaaacttgaa tctggaggaatccccgggcggattcacatttccaaagccacgctggactgcctcaacggt gactataatgtggaagagggtcacggtaaagagaggaacgaattcttgaggaagcataat atagagacctatttaattaagcagcctgaggagagtctgctgtctttgcccgaagacatc gtcaaggagtctgtgagctcctcagacaggagaaacagcggggcgacgttcacagaggga tcttggagccctgaactgcccttcgataacatagtggggaaacagaacactctggctgcc ctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcatgtccag tctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggtgat aaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctggag cacaagtattctcaaatgagggatgaagtattcaaatcaaacttggtctgtgcgtttatc gttcttctatttatcacggcaatacaaagcttgcttccttcttcaagagtgatgcccatg gccatccagttttccatcctgatcatgctgcactcggctctggtcctcatcactacggcg gaggattacaagtgcttgcccctggtcctccgaaaaacctgctgttggattaacgagacc tatttggccaggaacgtcatcatctttgcatctatcttgattaatttcctgggcgccatc ctaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaat tcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcacgggggtg ttggccatggtgacctgtgcggttttcctccgactcaactctgtccttaagctggctgtg ctcctgatcatgattgccatctatgccctgctgaccgagaccatctatgcaggcctcttt ctgcgctacgacaacctgaaccacagcggagaagatttcctggggaccaaggaagcgtcg ctgctgctaatggccatgttccttctagctgtgttctaccatggacagcagctggagtac acggcccgcctagacttcctgtggcgagtccaggccaaagaggaaatcaacgagatgaag gagctgagggagcacaatgagaacatgctgaggaacatcctgcccagccacgtggcccgc cacttcctggagaaggaccgggacaatgaggagctgtattctcaatcctatgatgcagtt ggggtgatgtttgcctccatcccggggtttgcagacttttactctcagaccgaaatgaac aaccaaggagtggaatgcctccgcctgctgaatgagatcattgctgacttcgatgagctg cttggtgaagaccggtttcaagacattgaaaagattaagaccattggtagtacctacatg gctgtgtcaggcctgtcacctgaaaagcagcaatgcgaggataagtggggacatttgtgc gccctggccgatttctccctcgccctgactgaaagcatccaggagatcaacaagcattcc ttcaacaatttcgagctccggattggcatcagccacggctcagtggtagctggcgtcatc ggcgctaagaaaccacagtacgacatctggggcaaaaccgtgaacctggcgagtcggatg gacagcacgggggtcagcggcaggatccaggtcccggaggagacctacctcatcctgaag gaccagggctttgcctttgactaccgaggggagatctacgtgaagggcatcagtgaacag gaagggaaaatcaaaacgtactttctcctgggaagagtccagcccaaccccttcatccta ccccccaggagactgcccgggcagtactccctggccgcggtggtcctgggcctcgtccag tccctcaacaggcagaggcagaagcagctgctgaacgagaacaacaacacgggcattatc aagggccactacaaccggcggactttgctgacacccagcgggccagagccgggagcccca gctgaaggcgccgacaagtccgagttgccatga

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