Budorcas taxicolor (takin): 128069000 Help Entry 128069000         CDS       T08909                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism btax  Budorcas taxicolor (takin) Pathway btax04022   cGMP-PKG signaling pathway btax04068   FoxO signaling pathway btax04081   Hormone signaling btax04140   Autophagy - animal btax04150   mTOR signaling pathway btax04151   PI3K-Akt signaling pathway btax04152   AMPK signaling pathway btax04211   Longevity regulating pathway btax04213   Longevity regulating pathway - multiple species btax04722   Neurotrophin signaling pathway btax04910   Insulin signaling pathway btax04920   Adipocytokine signaling pathway btax04923   Regulation of lipolysis in adipocytes btax04930   Type II diabetes mellitus btax04931   Insulin resistance btax04932   Non-alcoholic fatty liver disease btax04935   Growth hormone synthesis, secretion and action btax04960   Aldosterone-regulated sodium reabsorption btax05010   Alzheimer disease btax05206   MicroRNAs in cancer btax05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:btax00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     128069000 (IRS1)    04022 cGMP-PKG signaling pathway     128069000 (IRS1)    04151 PI3K-Akt signaling pathway     128069000 (IRS1)    04152 AMPK signaling pathway     128069000 (IRS1)    04150 mTOR signaling pathway     128069000 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     128069000 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     128069000 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     128069000 (IRS1)    04923 Regulation of lipolysis in adipocytes     128069000 (IRS1)    04920 Adipocytokine signaling pathway     128069000 (IRS1)    04935 Growth hormone synthesis, secretion and action     128069000 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     128069000 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     128069000 (IRS1)   09149 Aging    04211 Longevity regulating pathway     128069000 (IRS1)    04213 Longevity regulating pathway - multiple species     128069000 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     128069000 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     128069000 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     128069000 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     128069000 (IRS1)    04932 Non-alcoholic fatty liver disease     128069000 (IRS1)    04931 Insulin resistance     128069000 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  128069000 NCBI-ProteinID:  XP_052518247 LinkDB All DBs Position 2:complement(159591537..159653807) Genome browser AA seq 1235 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPN GHYILPRGGNGHRYVPAAGLGTSPALPGEEAAGAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRVPSYRHSAFVPTHSYPEEGLEMHPLERRVGHHR PDTSSLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDIGGGPSSGGSSSGAAPSGSSYGKLWTNGVGGHHSHALPHPKLPVES GSGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEL EEPRHHQHLRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCGARPEPGLPHLHHQVLQAH LPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQQPPPPLLLPPEPKSPGEYVNIEF GSDQPGYLSGPVASHSSPSIRCPSQLQPAPREEETGAEEYMNMDLGPGRRATWQESVGVQ PGRVGPAPPGAASVCRPTRAVPSSRGDYMTMQMGGPRQSYVDTSPVAPISYADMRTGVVE DASLPGATADAPSSSSTASVSSTAPPGTGELAARSALLGGPSAFTRVNLSPNRNQSAKVI RADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVAGSGGGSSSSAEDVKRHSSASFE NVWLRPGELGGAPKELAQLCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQPPPLPAP HQPLGSSQSGPTSRSSEDLSAYASITFQKQPEDLQ NT seq 3708 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggagacggacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgattcttcgtgctgcgggcggccagcgaggctgggggt ccggcgcgcctcgagtactacgagaacgaaaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctggagagctgcttcaacatcaacaagcgggcggactccaagaac aagcacctggtggctctctacacccgggacgagcactttgccatcgcggcagacagcgag gccgagcaggacagctggtaccaggccctcctgcagctgcacaaccgtgccaagggccac cacgacggggccgcggcgcctggggcgggaggcggcgggggcagctgcagtggcagctcc ggcctcggggaggccggggaggacttgagctacggggacgtgcccccaggacccgccttc aaggaggtctggcaggtgatcctgaaacccaagggcctgggtcagacaaagaacctgatc ggcatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag gcggcggccgtggtgctgcagctgatgaacatcaggcgctgtggccactcagagaacttc ttcttcatcgaagtgggccgttccgcagtgacgggcccgggggagttctggatgcaggtg gacgactccgtggtggcccagaacatgcatgagacaatcctggaggccatgcgggccatg agcgatgagttccgccctagaagcaagagccagtcctcctccaactgctccaaccccatt agtgtgcccctgaggaggcaccacctcaacaaccctccacccagccaggtggggctgacc cgccgctcgcgcaccgagagcatcacggccacctccccagccagcttggtgggcgggaag cagggctccttccgcgtgcgtgcctccagtgatggcgaaggcaccatgtctcgccctgcc tcagtggacggcagtcctgtgagtcctagcaccaacaggacccacgcccaccgccatcga ggcagctcccggctgcacccgcctctcaatcacagccgctccatccccatgccttcttct cgctgctcgccttccgccaccagccccgtcagtctgtcgtccagcagcacgagtggccac ggctccacctcagactgccttttcccgcggcggtctagtgcttctgtgtctggttccccc agtgatggcggcttcatctcctccgatgagtatggctccagtccctgcgatttccgaagc tccttccgcagcgtcaccccagattccctgggccacaccccgcccgcccggggtgaggaa gagctgagcaactacatctgcatgggaggcaagggggcctccaccctcactgcccccaat ggtcactacattttgccccggggtggcaatggtcaccgctacgtgccagccgcaggtttg ggcacaagcccagccctgccaggagaagaagcagccggtgcggcagatctggataatcgg ttccgaaagcggactcattctgcgggcacctcgcctaccatttcccaccagaaaaccccg tctcagtcctctgtggcttccattgaggaatatactgaaatgatgcccgcctacccacca ggaggtggcagtggaggccgagtacccagctaccggcactctgcctttgtgcccacccac tcctacccagaggagggtctggaaatgcaccccttggagcggcgtgtgggccaccaccgc ccagacacctccagccttcacaccgatgatggctacatgcccatgtccccaggggtggcc ccagtgcccggcagccggaaaggcagtggggactacatgcccatgagccctaagagcgtg tctgccccgcagcagatcatcaaccccattagacgtcatccccagagagtggaccccaac ggctacatgatgatgtccccaagcggcagctgctctcctgacattggaggtgggcccagc agcggcggcagcagcagcggcgccgccccttctgggagcagctatggcaagctctggaca aacggggtagggggccaccactctcacgccctgccacaccccaaacttccggtggagagc ggtagtggcaaactcctgtcttgtacaggtgactacatgaacatgtcgcccgttggggac tccaacaccagcagcccctccgactgctattatggccccgaggacccccagcacaagccc gtcctctcctactactcattgccaaggtccttcaagcatacccagcgccctggggagctg gaggagccccggcaccaccagcacctccgcctttcctcaagttccggtcgactcctctac gctgcggccgcagaagattcctcttcgtccaccagcagcgacagcctgggcgggggatat tgtggggctcggccagagcctggcctcccacatctccatcatcaggtccttcaggcccat ctgcctcgaaaggtggacacagctgcccagaccaacaaccgcctggctcggcccacgagg ctgtctctgggggatcccaaggccagcactttacctcgggcccgagagcagcagccgcca cccccgttgctgctccctccggagcctaagagcccaggggagtatgtgaatattgaattt gggagcgatcagccaggctacttatcaggcccggtggcatcccacagctcgccttccatc aggtgtccgtcccagctccagccagctcccagagaggaggagacgggcgcagaagagtat atgaacatggacctggggccgggccggagggccacctggcaggagagcgtgggggttcag ccgggcagggtgggcccggcgccccctggagctgctagcgtgtgcaggccgactagggca gtgcccagcagccgcggcgactatatgaccatgcagatgggcggtccccggcagagctac gtggacacctcacctgtcgcgcccatcagctacgccgacatgcggacgggtgtcgtggag gatgccagcctgcccggggccaccgcggacgctccctcctcatcctcgacggcctctgtt tcctccactgcacctccgggaacaggggagctggcggcccgctcggccctgcttgggggt ccgagcgccttcacgcgggtgaacctcagtcctaaccgcaaccagagtgccaaagtgatc cgtgccgacccgcaagggtgcaggaggcggcacagctctgagaccttctcctctacgccc agtgccacacgggtgggcaacacggtgcccttcggagccggggctgccgtcgcgggcagc ggtggcggcagcagcagcagcgccgaggatgtcaaacgccacagctctgcttccttcgag aacgtgtggctgaggcccggggagcttgggggagcccccaaggagctggcccaactgtgc ggggccgctgggggtttggagaatggtcttaactacatagacttggatttggtcaaggac ttcaaacagcgccctcaagagcgcccacctcaaccgcagcctcctccactcccggcccct catcagcctctgggcagtagtcagagcggccccaccagccgctccagcgaggatctaagc gcctatgccagcatcactttccagaagcagccagaggacctccagtag

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