Clostridium acetobutylicum ATCC 824: CA_C0578
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Entry
CA_C0578 CDS
T00056
Symbol
metH
Name
(GenBank) Cobalamine-dependent methionine synthase I (methyltransferase and cobalamine-binding domain)
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
cac
Clostridium acetobutylicum ATCC 824
Pathway
cac00270
Cysteine and methionine metabolism
cac00450
Selenocompound metabolism
cac00670
One carbon pool by folate
cac01100
Metabolic pathways
cac01110
Biosynthesis of secondary metabolites
cac01230
Biosynthesis of amino acids
cac04981
Folate transport and metabolism
Module
cac_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
cac00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CA_C0578 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
CA_C0578 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CA_C0578 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
CA_C0578 (metH)
04980 Cobalamin transport and metabolism
CA_C0578 (metH)
Enzymes [BR:
cac01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
CA_C0578 (metH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding
B12-binding_2
HemY_N
Motif
Other DBs
NCBI-ProteinID:
AAK78556
UniProt:
Q97LI3
LinkDB
All DBs
Position
complement(667538..671176)
Genome browser
AA seq
1212 aa
AA seq
DB search
MNSSLKNLLNNKILVLDGAMGTCIQSFNLDEGDFKGSLSCTCHSNQKGNNDVLNLTKPEI
IKEIHKRYLEAGADIIETNTFNATEISQKDYNMQDKIYDINFKGAKLAKEACTYYTKLNP
NKPRFAAGSIGPTNRTASLSPDVENPGFRNVTFDELCNAYKHQIEALIDGGVDLLLIETI
FDTLNARAAIFAAETVFENKKIKLPIIISGTIADKSGRILSGQTLDAFAESLKNENIIAI
GLNCSFGAEELIPFIKRLSETQNRYISFHPNAGLPNSLGEYEELPEETASIVKKLALEGH
LNIVGGCCGTTPEHIRAISSVVKGISPRKVPNLEPKTIYSGLENIKIDKNSNFINIGERT
NVAGSRKFARLIREKNYEEALTIARHQVENGAQIIDINFDDALLDARSEMETFLRLIASE
PEISKVPVMIDSSNFEVLKVGLKSIQGKAIVNSISLKVGEEKFIEEAKFIKNFGAGVVVM
AFDEEGQAATYERKIEICKRAYTILTEKVEFPPENIIFDPNILSIATGIEEHDNYAVNYI
KAVKWIKENLPYAKVSGGVSNLSFSFRGNDAIRRAMHSVFLYHAINAGMDMGIVNPAMID
LYDDIDKDLLEKVENVVLNKSSNASESLLEFAQTYKKTTETLEKHEDEWRQKSPSERLSY
ALVKGNVEFIEEDIEEARKEYTNALEIIEVPLMNGMKKVGKLFGEGKMFLPQVVKSARVM
KKAVECLLPYINEEKSKNHNKSAGKVVFATVKGDVHDIGKNIVSVVLSCNNFEVIDLGVM
VPPETILETAKRENADIIALSGLITPSLNEMAYVAEEMKRLNFDIPLMVGGAATSKTHTA
LKLATKYKYVVHSTDASDAVTVAKNLMSENKFTFLEKLNEEYSKIRETFSTNKIELISIQ
NARKNRFTIDWNKTKITEPKFVGIKKLQAVPINELRKYIDWTFFFTSWDMGMNYPKIMKD
PKYGAEAQKLFKDANEMLDLLQKENLITCNGVFGIFPANSVNDDIEIYTDKGTVTINTLR
QQQILKDSDYKALSDYIAPKGIGIKDYIGGFIVTAGIGAKEYSDKLKKKCDDYGATMLKL
ICDRLAEAFSELLHLRVRKEYWGYSQDENLSLEKLLKGSYRGIKPAIGYPSIPDHSEKAK
LFDLLLGKTSIGVELTESYMMNPTSSVCGLYFANERAKYFNINKIGKDQLEDYAVRSNKD
INEIKKLLDTLL
NT seq
3639 nt
NT seq
+upstream
nt +downstream
nt
atgaattcttcactaaagaatttgttaaataacaaaattttagttttagatggtgctatg
ggaacatgtattcaatcctttaatctagatgaaggcgactttaaaggttccttatcttgt
acatgtcattccaatcaaaaaggaaacaatgatgttttaaatttaaccaagccagaaata
ataaaagaaatccacaagagataccttgaagctggcgcagatataatagaaacaaacact
tttaacgctactgaaatatcacaaaaagattataatatgcaagataaaatatatgatatt
aattttaagggggcaaaactcgcaaaggaagcttgtacttactacacaaaactaaatcct
aataagcctagatttgctgctggttctattgggcctacaaatagaactgcttctctatct
ccagatgttgaaaatcctggttttagaaatgtaacctttgatgagctatgtaatgcctat
aaacatcaaatagaggctctaatagatggaggtgtagaccttcttttaattgaaactata
tttgatactttaaacgctagagcagcaatctttgcagcagaaacagtatttgaaaataaa
aaaataaaacttcctattataatttcagggacaatagctgataaaagtggaagaatatta
tccggtcaaactcttgacgcttttgcagaaagtttaaaaaacgaaaatataattgctata
gggcttaattgttcctttggtgctgaagaacttataccttttataaaaagactctctgaa
acacaaaatagatatatatcctttcatccaaacgcaggacttccaaactcccttggtgaa
tatgaagaactgccagaggaaactgctagcattgtaaaaaaattagcacttgaaggacat
ttaaatatagttggaggctgctgtggcactacaccagaacatataagagcaataagcagc
gtagttaaaggcatttctccaagaaaagttccaaacttggaacccaaaacaatttacagc
ggactagaaaacataaaaattgataagaacagtaacttcataaatataggcgaaagaaca
aatgtagcgggctcaagaaaattcgcaaggcttatacgtgaaaaaaattatgaggaggct
ctaaccattgcaagacatcaggttgaaaatggtgcccaaattatagatataaattttgat
gatgcacttttagatgctcgctctgaaatggaaacatttttaagacttattgcaagtgaa
cctgaaatatcaaaagttccagttatgatagactcctctaattttgaagttttaaaagtt
ggattaaagtctattcaaggtaaagccatagtaaattccataagtcttaaggttggagaa
gaaaagttcattgaagaggcaaaatttataaagaactttggcgctggcgtagttgtaatg
gcctttgacgaagaaggtcaagcagctacttatgaaagaaaaattgaaatctgcaagaga
gcttatactattctcacagaaaaagttgagtttccacctgaaaatataatatttgatcca
aatatactatctatagcgacaggaattgaagaacatgacaactatgcagttaattacata
aaagctgttaaatggataaaagagaatctaccatacgctaaagtcagcggtggagttagc
aacctctccttttcttttaggggtaatgacgcaataagaagagctatgcattctgttttc
ctttaccatgcaataaacgctggaatggatatgggtattgttaatccagcaatgattgat
ttatatgacgatatagataaggatcttctcgaaaaggttgagaatgttgtactaaataaa
tcatctaacgcttctgaatcattactagaatttgctcaaacgtataaaaagacgactgaa
accttagaaaagcacgaggatgaatggcgacaaaaaagcccaagtgaaaggttgagttat
gctttagttaaaggaaatgttgaatttattgaagaagatatagaagaagcaagaaaagag
tatacaaatgcacttgaaattatagaggttcctttaatgaatggaatgaaaaaagtgggt
aaactttttggagagggaaaaatgtttcttcctcaagtagtaaaaagtgctagagttatg
aaaaaggctgttgaatgtcttcttccctatataaacgaagaaaagtctaaaaatcacaat
aaaagtgctggtaaggttgtatttgcaactgttaaaggcgatgttcatgacataggcaaa
aatatcgtatctgtagttctttcctgcaacaattttgaagttatagatttaggagtaatg
gttccccctgaaaccatacttgaaacggcaaaacgtgaaaatgcagatatcattgcttta
agtggtttaattacaccttctcttaatgaaatggcttatgtagctgaagaaatgaaaagg
cttaattttgatataccacttatggtgggtggtgctgctacctcaaaaactcacacagct
ttaaaactagctacgaaatataaatatgtagtacacagtactgatgcttcagatgctgtt
accgtagccaaaaatctaatgagtgaaaacaaatttactttcttagaaaaattaaatgaa
gagtattctaaaataagagagaccttctctactaataagattgaacttatctccattcaa
aacgcaagaaaaaacagatttactattgactggaataaaactaaaataactgaacctaaa
tttgtcggtataaaaaaattacaagctgtacctataaatgaattaagaaagtatatagat
tggactttcttctttacgtcttgggatatgggaatgaattaccccaaaataatgaaagat
cctaaatacggagctgaagctcaaaaactctttaaggatgccaatgaaatgcttgattta
ttgcaaaaagaaaatttaatcacttgtaatggagtttttggaatattcccagctaattct
gttaatgatgatatagaaatctacactgataaaggaactgtaaccataaatactcttcgt
cagcagcagatacttaaagacagcgattataaagctctatctgattatatcgctccaaag
ggtattggcatcaaagattatataggtggttttattgtaactgctggaataggtgcaaag
gaatattccgataaattaaagaaaaaatgcgacgattatggagctactatgcttaaactt
atatgcgatagacttgcagaggccttttcagaacttcttcacctaagggtaagaaaagaa
tactggggatactctcaagatgaaaacttatccttagaaaaacttcttaaaggaagttac
agagggataaaaccagctattggatatccttctattcccgatcactctgaaaaagcaaag
ttatttgatttacttttaggtaaaacttcaataggagtggaattgacggaaagttatatg
atgaatccaacttcaagtgtatgcggtttgtattttgcaaatgaacgagcaaaatacttt
aatataaataaaataggaaaagatcaacttgaggactatgctgttcgaagtaataaagac
attaatgaaataaaaaaattattagatactctgttataa
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