KEGG   Clostridium acetobutylicum ATCC 824: CA_C1195
Entry
CA_C1195          CDS       T00056                                 
Symbol
ligA
Name
(GenBank) DNA ligase (NAD dependent), LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
cac  Clostridium acetobutylicum ATCC 824
Pathway
cac03030  DNA replication
cac03410  Base excision repair
cac03420  Nucleotide excision repair
cac03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:cac00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    CA_C1195 (ligA)
   03410 Base excision repair
    CA_C1195 (ligA)
   03420 Nucleotide excision repair
    CA_C1195 (ligA)
   03430 Mismatch repair
    CA_C1195 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:cac03032]
    CA_C1195 (ligA)
   03400 DNA repair and recombination proteins [BR:cac03400]
    CA_C1195 (ligA)
Enzymes [BR:cac01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     CA_C1195 (ligA)
DNA replication proteins [BR:cac03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     CA_C1195 (ligA)
DNA repair and recombination proteins [BR:cac03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     CA_C1195 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     CA_C1195 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     CA_C1195 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      CA_C1195 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 PTCB-BRCT 5_3_exonuc Nlig-Ia HHH RNA_lig_T4_1 BRCT_2 DNA_ligase_ZBD RNA_ligase POLH-Rev1_HhH Zn_ribbon_3 RNA_pol_A_CTD DUF7501
Other DBs
NCBI-ProteinID: AAK79167
UniProt: Q97JS8
LinkDB
Position
1343492..1345483
AA seq 663 aa
MKLIEDLIEKLNKYSYSYYVLDNPIVADKEYDIMYDELKRLEEETEYINPNSPTQRVGDI
ILDKFEKTHHKNKLWSLDKAQKKDEVKAFVNKCVKFVEQYNLTHSEKLPSPQFVVTQKLD
GLTINCSYNESRLIKSATRGTGEIGEDITEQSKTILNLPNAINYSGEIDVHGEALMTKNA
LEQYNSNLKVNETPLKNLRNGAAGALRNLNIKETARRKLVAQFYDLSYTDKKLKKYSEIL
LFLKSQGFNITEYNICNNFDEINQAIDNIGEVRSSLQYDIDGVVIRLNDIETSRLMGYTI
KCPKYAIAYKFKAKETTTKLIDVEWNVGRSGRINPTAILEPVELAGVIVKRATLNNMDDI
KRKKIKKGARVFLRRSNDVIPEIMGVTEETEGETKEIEAPTICPYCGSEIVKEGVHLFCE
NTLSCKPQMVKSIVHFASRKAMNIEGFSEKTAEQLFEKLNIKSISDLYRITKEELMSLDK
FKDKKASNLINAIEKSKECDLDSFVYSLGIPNVGKKTATDLCKQFKSFENIKKASYFELI
LVQDIGSIVAKSIVDFFKQEKIEKSLNELFKLGVKPSYEESEVSESVFNDKTVVATGSLQ
NYSRTEIKEKLESLGAKVAGSVSKKTDYVIAGENAGSKYDKAVALGVKILTEEKFEELIE
SVK
NT seq 1992 nt   +upstreamnt  +downstreamnt
atgaaactaattgaagatttaattgaaaagttaaataaatattcctacagctattatgtg
cttgataatccaattgtagctgataaggaatatgatataatgtatgatgagcttaaaaga
ttagaagaagaaacagagtatattaatcctaatagtccaactcaaagggttggtgatatt
atccttgataaatttgagaaaacacatcataaaaataaactttggagtcttgataaggct
caaaagaaggatgaagttaaagcttttgtaaataagtgtgttaaatttgtagagcaatat
aatttaacacatagtgaaaaattgccttcaccacaattcgttgtaacacaaaagcttgat
ggacttactataaattgttcatacaatgaaagtagattaattaaatctgcaactaggggg
acaggggaaataggagaagatattacagaacaaagtaaaaccattctcaatcttcctaat
gctataaattatagtggagaaattgatgttcatggagaagcattaatgacaaaaaatgct
ttagaacaatataatagtaatttaaaagtaaatgaaacaccacttaaaaacttaaggaat
ggtgcagcaggagcattgagaaatttaaacataaaagaaactgcaagaagaaagctagta
gctcaattttatgatcttagctatacagataagaagttaaaaaaatatagtgaaatttta
ttatttttaaaatctcaaggatttaacataactgagtacaatatttgtaataattttgat
gaaattaaccaagctattgataatataggagaggtaagaagtagcttacaatacgatata
gatggagttgtaattcgattaaatgatatagaaacgagtagattaatgggctatacaata
aagtgtcctaaatatgcaatagcttataaatttaaagcaaaagaaacaactacaaagcta
atagatgtagaatggaacgtgggcagaagtggaagaatcaatccaacagctattttagaa
cctgtagaattagctggagtaatagttaaaagagctacattaaataatatggatgatata
aagaggaaaaagattaaaaaaggtgctagagtatttctaagaagatctaatgatgtaata
ccagagattatgggagttacagaagagacagagggagaaacgaaggaaatagaagcacca
acaatatgcccatattgcggcagtgaaatagtaaaagaaggtgtacatttattttgtgaa
aatactttgtcctgtaaaccccaaatggtaaaaagtatagtccattttgctagcagaaaa
gctatgaatatagaaggctttagtgagaaaacagcagaacaattatttgagaaattaaac
ataaaaagcatatctgacttatatagaataactaaagaagaattaatgtcattggataag
tttaaagacaaaaaggctagtaatcttataaatgctatagagaaaagtaaggaatgtgat
cttgattcatttgtatactcattgggtataccaaatgtaggaaaaaaaacagcaacagat
ttatgtaagcaatttaaaagctttgagaacataaaaaaagcttcttattttgagcttatc
ttggttcaagatataggatcaattgttgcaaaaagtattgttgatttttttaaacaagaa
aaaatagaaaaaagtctaaatgaattatttaaacttggagtaaaaccatcttatgaagaa
agtgaagtttcagaaagtgtatttaatgataaaactgtagttgcaacaggaagtcttcaa
aattatagcagaacagaaataaaagaaaagttggagagccttggtgctaaggttgctgga
agtgttagtaaaaaaactgattatgtaatagcaggtgaaaatgcaggatctaaatatgac
aaagctgtagcacttggagttaaaatattaactgaagaaaagtttgaagaattaatagaa
agtgtaaagtag

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