Cutibacterium acnes KCOM 1861 (= ChDC B594): RN83_05305
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Entry
RN83_05305 CDS
T04624
Name
(GenBank) alpha-ketoglutarate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
cacn
Cutibacterium acnes KCOM 1861 (= ChDC B594)
Pathway
cacn00010
Glycolysis / Gluconeogenesis
cacn00020
Citrate cycle (TCA cycle)
cacn00620
Pyruvate metabolism
cacn00785
Lipoic acid metabolism
cacn01100
Metabolic pathways
cacn01110
Biosynthesis of secondary metabolites
cacn01120
Microbial metabolism in diverse environments
cacn01200
Carbon metabolism
cacn01210
2-Oxocarboxylic acid metabolism
Module
cacn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cacn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
RN83_05305
00020 Citrate cycle (TCA cycle)
RN83_05305
00620 Pyruvate metabolism
RN83_05305
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RN83_05305
Enzymes [BR:
cacn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
RN83_05305
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF2470
Motif
Other DBs
NCBI-ProteinID:
ALD69571
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Position
1144334..1147120
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AA seq
928 aa
AA seq
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MCVAVDEKGPGVIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVL
LKMLERARSHSRLGLSALTSTDYINTIAAEDEEEYPGDAEIERNIRRLLRWNSAITVHRA
QRPGIGVGGHISTYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGMYARAFLEGR
LSEDDLDGFRQEKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMDSIYQASMNKYLTNR
GVKDCADQHVWAFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKI
VQELEAVFRGAGWNVIKVIWGSGWDPLLQADRDGALVDIMNNTRDGDYQTFKANDGAYVR
EHFFGRDPRTAKMVEKWTDEQIWALRRGGHDYRKIYNAYKAATEFKGAPTVVLACTIKGY
DLGTHFAGRNATHQMKKLALDDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQY
LMERRRALGGFVPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKN
FAPHVVPIIPDEARTFGMDSFFPTIKIYNPHGQNYTPVDHELMLSYREAKNGQIIHTGIN
EAGSAAAFIAAGSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTKGFIIGATAGR
TTLTGEGTQHMDGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLT
VYNEPIVQPAEPEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQL
LKGDFGVVADVWSVTSWNNLRRDAMEAEEQTFLHPEQGRRTPYITQCLADAPGPVVATTD
YTRQVPDQIAQWVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQMLVERGEVP
EDWPAKAAEKYDLLNVNAGASGNAGGDA
NT seq
2787 nt
NT seq
+upstream
nt +downstream
nt
ttgtgcgtcgctgtcgatgagaaaggacccggcgtgatcccacgcgaagaacgcggacca
gtcctcaacggacttccgacaaccctgcctgacgtcgatcccgaggagacccaggagtgg
atcgagtccctcgacaagatggtcgagactgatggtccgaaccgtgcccggatcgtgctg
ctcaagatgttggagcgggctcgtagtcacagtcgtctcgggctgtcagcgctcacctcc
accgactacatcaacaccattgcagccgaggacgaggaagaataccccggcgacgccgag
atcgagcggaacatccgtcgtctgctgcgctggaattccgccattaccgtgcatcgcgcg
cagcgtcccggtattggcgtcggcggtcatatctccacctatgcctctgccgtgaccctc
tatgaggtcggtcagaaccacttctggcgcgggcaggacgcccccggcggcggtgaccaa
gttttcttccaggggcacgccgcgcccggtatgtacgctcgcgcgttcttggagggacgt
ctcagtgaggacgacctcgatgggttccgtcaggagaagtcgaaggccgggcatggtcta
ccctcttacccgcaccctcgcatgttgcccgacttctggcagttcccgacggtgtcgatg
ggtctgggcccgatggattccatttaccaggcgtctatgaataagtacctcaccaatcgc
ggtgtcaaggactgcgcagatcagcacgtgtgggctttccttggcgacggtgagatggac
gagccggagtcgcgcggattcctgcaggtcgctgccaacgaggagctcgacaacctcacc
ttcgtcatcaactgcaacctgcagcgtctagacggaccggtgcgtggcaacggcaagatt
gtccaggaacttgaggctgtcttccgtggtgctggctggaacgtcatcaaggtcatttgg
ggatctggctgggacccgctgctgcaggcagaccgtgacggtgccctcgttgatatcatg
aacaacacccgtgatggcgactaccaaaccttcaaggccaacgacggcgcctatgtccgc
gagcacttctttggccgcgacccgcgcactgccaagatggtcgagaagtggactgacgaa
cagatttgggcgttacgccgtggcggtcacgactaccgcaagatttacaacgcctacaag
gcggctacggagttcaagggagcgccgaccgtggtgcttgcctgcactattaaaggttac
gatcttggtactcactttgcgggccgcaacgctacccaccagatgaagaagctggccctt
gacgacctcaagcagttccgcgatcgtctcgaaattccgatttcggacaaggtgctggag
gccgacccctaccgtgctccctacttccatcccggagccgacgacgagcgcatccagtac
ctcatggagcgtcgtcgcgctctcggcggtttcgtgccggagcgccgtacgaggcacacg
ccactacccatcccggcgcagaaggccttcgatggtgtcaagcgtgggtcgggcaaacag
gaggtcgccaccacgatggccttcgtgcgtctgctcaaggaccttatgcgcgacaagaat
ttcgctccgcacgtcgtcccgatcattcctgacgaggcccgtacctttggcatggactcg
ttcttcccgacgatcaagatctacaatcctcacggccagaactacacccctgtcgaccac
gagctcatgctcagctaccgcgaggccaagaacgggcagatcattcacactggcatcaat
gaggctggttcagcggctgctttcattgccgcaggctcggcatactccactcagggcgta
ccgatggtgccgatctacctgttctactcgatgttcgggttccagcgtaccggtgattct
ttctgggcagctggtgatcagatgacgaagggattcattattggcgccactgccggacgc
accacgctgaccggtgagggcacccagcacatggatggccattcgccggttctggctgcg
acgaacccagcggtcatctcctacgatccggcttattcttacgagatctcccacattgtt
caggcaggtctggagcacatgtacggcgagaacgccgaagacgtcatgtactacctgacg
gtgtacaacgagccgatcgtccagccggctgagccagagggcgttgacgccgagggcatc
gtcaagggcatgtacctgctctcgaagggctcctttgagggcgtcggtgaggatgcccgc
cgcgttcagctgctggcctccggcgtcgccgtgccgtgggccattgaggctcagcagctc
cttaagggtgactttggcgttgttgccgacgtgtggtcggtgacgtcgtggaacaaccta
cgtcgtgacgctatggaggccgaggaacagactttcctacaccccgaacagggcaggcgc
accccgtatatcacccaatgcctggccgacgcccctggtccagtcgttgcgaccaccgat
tacacgcgtcaggtgcccgatcagatcgcccagtgggtgccgggggattatgcctcctta
ggtgctgacggattcgggttctccgacacccgtgcggcagcgcgccgattcttccacatc
gatggaccgtccatgacagtgcgtgccctccagatgcttgtcgagcgtggtgaggttccc
gaggactggcctgccaaggctgccgagaagtacgacctcctcaacgtcaacgcgggggcg
tccggtaatgctggtggcgacgcctga
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