Clostridium acetobutylicum DSM 1731: SMB_G0592
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Entry
SMB_G0592 CDS
T01548
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
cae
Clostridium acetobutylicum DSM 1731
Pathway
cae00270
Cysteine and methionine metabolism
cae00450
Selenocompound metabolism
cae00670
One carbon pool by folate
cae01100
Metabolic pathways
cae01110
Biosynthesis of secondary metabolites
cae01230
Biosynthesis of amino acids
cae04981
Folate transport and metabolism
Module
cae_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
cae00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SMB_G0592 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SMB_G0592 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SMB_G0592 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SMB_G0592 (metH)
04980 Cobalamin transport and metabolism
SMB_G0592 (metH)
Enzymes [BR:
cae01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SMB_G0592 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding
B12-binding_2
HemY_N
Motif
Other DBs
NCBI-ProteinID:
AEI34028
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All DBs
Position
complement(667524..671162)
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AA seq
1212 aa
AA seq
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MNSSLKNLLNNKILVLDGAMGTCIQSFNLDEGDFKGSLSCTCHSNQKGNNDVLNLTKPEI
IKEIHKRYLEAGADIIETNTFNATEISQKDYNMQDKIYDINFKGAKLAKEACTYYTKLNP
NKPRFAAGSIGPTNRTASLSPDVENPGFRNVTFDELCNAYKHQIEALIDGGVDLLLIETI
FDTLNARAAIFAAETVFENKKIKLPIIISGTIADKSGRILSGQTLDAFAESLKNENIIAI
GLNCSFGAEELIPFIKRLSETQNRYISFHPNAGLPNSLGEYEELPEETASIVKKLALEGH
LNIVGGCCGTTPEHIRAISSVVKGISPRKVPNLEPKTIYSGLENIKIDKNSNFINIGERT
NVAGSRKFARLIREKNYEEALTIARHQVENGAQIIDINFDDALLDARSEMETFLRLIASE
PEISKVPVMIDSSNFEVLKVGLKSIQGKAIVNSISLKVGEEKFIEEAKFIKNFGAGVVVM
AFDEEGQAATYERKIEICKRAYTILTEKVEFPPENIIFDPNILSIATGIEEHDNYAVNYI
KAVKWIKENLPYAKVSGGVSNLSFSFRGNDAIRRAMHSVFLYHAINAGMDMGIVNPAMID
LYDDIDKDLLEKVENVVLNKSSNASESLLEFAQTYKKTTETLEKHEDEWRQKSPSERLSY
ALVKGNVEFIEEDIEEARKEYTNALEIIEVPLMNGMKKVGKLFGEGKMFLPQVVKSARVM
KKAVECLLPYINEEKSKNHNKSAGKVVFATVKGDVHDIGKNIVSVVLSCNNFEVIDLGVM
VPPETILETAKRENADIIALSGLITPSLNEMAYVAEEMKRLNFDIPLMVGGAATSKTHTA
LKLATKYKYVVHSTDASDAVTVAKNLMSENKFTFLEKLNEEYSKIRETFSTNKIELISIQ
NARKNRFTIDWNKTKITEPKFVGIKKLQAVPINELRKYIDWTFFFTSWDMGMNYPKIMKD
PKYGAEAQKLFKDANEMLDLLQKENLITCNGVFGIFPANSVNDDIEIYTDKGTVTINTLR
QQQILKDSDYKALSDYIAPKGIGIKDYIGGFIVTAGIGAKEYSDKLKKKCDDYGATMLKL
ICDRLAEAFSELLHLRVRKEYWGYSQDENLSLEKLLKGSYRGIKPAIGYPSIPDHSEKAK
LFDLLLGKTSIGVELTESYMMNPTSSVCGLYFANERAKYFNINKIGKDQLEDYAVRSNKD
INEIKKLLDTLL
NT seq
3639 nt
NT seq
+upstream
nt +downstream
nt
atgaattcttcactaaagaatttgttaaataacaaaattttagttttagatggtgctatg
ggaacatgtattcaatcctttaatctagatgaaggcgactttaaaggttccttatcttgt
acatgtcattccaatcaaaaaggaaacaatgatgttttaaatttaaccaagccagaaata
ataaaagaaatccacaagagataccttgaagctggcgcagatataatagaaacaaacact
tttaacgctactgaaatatcacaaaaagattataatatgcaagataaaatatatgatatt
aattttaagggggcaaaactcgcaaaggaagcttgtacttactacacaaaactaaatcct
aataagcctagatttgctgctggttctattgggcctacaaatagaactgcttctctatct
ccagatgttgaaaatcctggttttagaaatgtaacctttgatgagctatgtaatgcctat
aaacatcaaatagaggctctaatagatggaggtgtagaccttcttttaattgaaactata
tttgatactttaaacgctagagcagcaatctttgcagcagaaacagtatttgaaaataaa
aaaataaaacttcctattataatttcagggacaatagctgataaaagtggaagaatatta
tccggtcaaactcttgacgcttttgcagaaagtttaaaaaacgaaaatataattgctata
gggcttaattgttcctttggtgctgaagaacttataccttttataaaaagactctctgaa
acacaaaatagatatatatcctttcatccaaacgcaggacttccaaactcccttggtgaa
tatgaagaactgccagaggaaactgctagcattgtaaaaaaattagcacttgaaggacat
ttaaatatagttggaggctgctgtggcactacaccagaacatataagagcaataagcagc
gtagttaaaggcatttctccaagaaaagttccaaacttggaacccaaaacaatttacagc
ggactagaaaacataaaaattgataagaacagtaacttcataaatataggcgaaagaaca
aatgtagcgggctcaagaaaattcgcaaggcttatacgtgaaaaaaattatgaggaggct
ctaaccattgcaagacatcaggttgaaaatggtgcccaaattatagatataaattttgat
gatgcacttttagatgctcgctctgaaatggaaacatttttaagacttattgcaagtgaa
cctgaaatatcaaaagttccagttatgatagactcctctaattttgaagttttaaaagtt
ggattaaagtctattcaaggtaaagccatagtaaattccataagtcttaaggttggagaa
gaaaagttcattgaagaggcaaaatttataaagaactttggcgctggcgtagttgtaatg
gcctttgacgaagaaggtcaagcagctacttatgaaagaaaaattgaaatctgcaagaga
gcttatactattctcacagaaaaagttgagtttccacctgaaaatataatatttgatcca
aatatactatctatagcgacaggaattgaagaacatgacaactatgcagttaattacata
aaagctgttaaatggataaaagagaatctaccatacgctaaagtcagcggtggagttagc
aacctctccttttcttttaggggtaatgacgcaataagaagagctatgcattctgttttc
ctttaccatgcaataaacgctggaatggatatgggtattgttaatccagcaatgattgat
ttatatgacgatatagataaggatcttctcgaaaaggttgagaatgttgtactaaataaa
tcatctaacgcttctgaatcattactagaatttgctcaaacgtataaaaagacgactgaa
accttagaaaagcacgaggatgaatggcgacaaaaaagcccaagtgaaaggttgagttat
gctttagttaaaggaaatgttgaatttattgaagaagatatagaagaagcaagaaaagag
tatacaaatgcacttgaaattatagaggttcctttaatgaatggaatgaaaaaagtgggt
aaactttttggagagggaaaaatgtttcttcctcaagtagtaaaaagtgctagagttatg
aaaaaggctgttgaatgtcttcttccctatataaacgaagaaaagtctaaaaatcacaat
aaaagtgctggtaaggttgtatttgcaactgttaaaggcgatgttcatgacataggcaaa
aatatcgtatctgtagttctttcctgcaacaattttgaagttatagatttaggagtaatg
gttccccctgaaaccatacttgaaacggcaaaacgtgaaaatgcagatatcattgcttta
agtggtttaattacaccttctcttaatgaaatggcttatgtagctgaagaaatgaaaagg
cttaattttgatataccacttatggtgggtggtgctgctacctcaaaaactcacacagct
ttaaaactagctacgaaatataaatatgtagtacacagtactgatgcttcagatgctgtt
accgtagccaaaaatctaatgagtgaaaacaaatttactttcttagaaaaattaaatgaa
gagtattctaaaataagagagaccttctctactaataagattgaacttatctccattcaa
aacgcaagaaaaaacagatttactattgactggaataaaactaaaataactgaacctaaa
tttgtcggtataaaaaaattacaagctgtacctataaatgaattaagaaagtatatagat
tggactttcttctttacgtcttgggatatgggaatgaattaccccaaaataatgaaagat
cctaaatacggagctgaagctcaaaaactctttaaggatgccaatgaaatgcttgattta
ttgcaaaaagaaaatttaatcacttgtaatggagtttttggaatattcccagctaattct
gttaatgatgatatagaaatctacactgataaaggaactgtaaccataaatactcttcgt
cagcagcagatacttaaagacagcgattataaagctctatctgattatatcgctccaaag
ggtattggcatcaaagattatataggtggttttattgtaactgctggaataggtgcaaag
gaatattccgataaattaaagaaaaaatgcgacgattatggagctactatgcttaaactt
atatgcgatagacttgcagaggccttttcagaacttcttcacctaagggtaagaaaagaa
tactggggatactctcaagatgaaaacttatccttagaaaaacttcttaaaggaagttac
agagggataaaaccagctattggatatccttctattcccgatcactctgaaaaagcaaag
ttatttgatttacttttaggtaaaacttcaataggagtggaattgacggaaagttatatg
atgaatccaacttcaagtgtatgcggtttgtattttgcaaatgaacgagcaaaatacttt
aatataaataaaataggaaaagatcaacttgaggactatgctgttcgaagtaataaagac
attaatgaaataaaaaaattattagatactctgttataa
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