KEGG   Citrobacter amalonaticus Y19: F384_22095
Entry
F384_22095        CDS       T03934                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
cama  Citrobacter amalonaticus Y19
Pathway
cama00270  Cysteine and methionine metabolism
cama00450  Selenocompound metabolism
cama00670  One carbon pool by folate
cama01100  Metabolic pathways
cama01110  Biosynthesis of secondary metabolites
cama01230  Biosynthesis of amino acids
cama04980  Cobalamin transport and metabolism
cama04981  Folate transport and metabolism
Module
cama_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:cama00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    F384_22095 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    F384_22095 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    F384_22095 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    F384_22095 (metH)
   04980 Cobalamin transport and metabolism
    F384_22095 (metH)
Enzymes [BR:cama01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     F384_22095 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AKE61058
UniProt: A0A0F6RHM1
LinkDB
Position
4780626..4784309
AA seq 1227 aa
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLSEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFDAGADIIETNTFNSTPIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVSAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIFAVKEELEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEP
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAGQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVEGLAPRQLPEIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEIFTHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPADLRDAVEDVILNRRDDGTERLLELAEKYRGSKSDETANAQLAEWRTWEVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLAAARENDLAFDWENYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAKRLFNDANDMLDKLSAEKSLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLSDFVAPKLSGKADYIGAFAVTGGLEEDALAEAFEAQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDYAFRKGMSVSEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggcatgggcacgatgatccagagctaccgcctgagtgaagaggatttccgtggtgaa
cgctttgccgactggccgtgcgacctgaaaggcaacaatgacctgctggtgctgagtaag
ccagaggtgatcgccgctattcacaacgcgtactttgacgcgggcgcggacatcattgaa
accaacaccttcaactccactcctatcgcgatggcggattaccagatggaatccctgtcg
gcggagatcaactttgccgccgcgaaactggcgcgcgcttgcgccgatgagtggaccgct
cgtaccccggaaaaaccgcgctatgtggcgggtgttctcggcccaaccaaccgcaccgcg
tcgatctcgccggatgtgaatgacccggcatttcgtaatatcacttttgaccagttggtg
tccgcttatcgcgaatccaccaaagcgctggtggaaggcggcagtgacctgattctaatt
gaaaccgtctttgatacgctgaacgcgaaagccgcgatttttgccgttaaagaagagctg
gaagcgctgggcgtcgacctgccgatcatgatttccggcaccatcaccgatgcttcaggc
cggacgctttccggtcagacaacggaggcgttttataactccctgcgccatgccgaacct
cttaccttcggtctcaactgtgcgctgggaccggatgaactgcgccagtatgtgcaggag
ctttcacgcattgctgaatgctacgtgacggcgcacccgaacgccgggttgcccaacgct
ttcggtgaatacgatctggatgccgatacgatggcgggtcagatccgcgagtgggccgaa
gcaggattcctgaacatcgtcggcggctgctgcggcaccacgccggaacacattgcggcg
atgagccgcgccgtcgagggattggcgccgcgtcagttgccggagatccccgttgcctgc
cgcctgtccggtctcgagccgctgaatattggcgatgacagcctgtttgtgaacgtcggt
gaacgtaccaacgtcaccggttccgctaaatttaagcgcctgatcaaagaagaaaaatac
aacgaagcgctggatgttgcccgtcagcaggtagaaagcggtgcgcagattatcgatatc
aatatggatgaggggatgctcgacgccgaagcggcgatggtgcgcttcctcaacctgatc
gccggtgagccggacattgctcgtgtgccgatcatgattgactcctcaaaatgggaagtc
atcgagaaagggctgaagtgtattcaggggaaaggcatcgttaactccatctccatgaaa
gagggggttgagatcttcacccaccacgcgaagctgctgcgtcgctacggtgcggcggtg
gtggtgatggcttttgatgaacagggccaggcggatacccgcgcgcgtaaaatcgagatt
tgccgccgggcgtacaagatcctcaccgaagaggtgggtttcccgccggaagacattatt
ttcgacccgaatattttcgcggtagcgaccgggattgaagagcacaacaactacgcgcag
gactttatcggcgcgtgtgaagacatcaaacgcgagctgccgcatgcgctgatctccggc
ggcgtgtccaacgtgtcgttctcgtttcgcggtaacgatccggtgcgcgaagccattcac
gcggtgttcctctactacgccatccgcaacggtatggacatggggattgtgaacgccgga
caactggcgatttacgacgatttgcctgctgacctgcgcgacgcggtcgaggacgtgatc
ctcaaccgtcgtgatgacggcactgagcgactgctggaactggcggagaaataccgtggc
agcaagagcgatgagacggccaacgcccagctggcggaatggcgcacctgggaagttaaa
aaacgcctcgaatactcgctggttaaaggcatcaccgaatttatcgagcaggacaccgaa
gaggcgcgtcagcaggccgcccgtccgattgaagtgattgaagggccgctgatggacggt
atgaacgtcgtcggcgacctgttcggcgagggtaagatgttcctgccgcaggtggtgaaa
tccgcccgcgtcatgaaacaggcggtggcgtatctcgaaccgtttatcgaagccagcaaa
gagaaaggctccagcaacggcaagatggtgatcgccaccgtgaaaggcgacgttcacgat
atcggcaagaacattgttggcgtggtcctgcaatgtaacaactacgaaattgtcgatctt
ggcgtgatggtgccggcagagaagatcctcagaaccgcgaaagaggtgaatgcggatctg
atcggcctctccgggctgattaccccgtcgctggacgaaatggtcaacgtggcgaaagag
atggagcgtcagggattcactattccgctgctgattggcggggcgacgacctcgaaagcg
catacggcggtgaaaatcgagcagaactacagtggtcccacggtttatgtgcagaacgcc
tcgcgcaccgtcggcgtggtcgccgcgctgctttccgatacccagcgcgatgactttgtc
gcccgtacccgcaaagagtatgaaactgtgcgcatccagcatgggcgtaagaaaccccgc
acgccgccggtgacactggcggcagcgcgtgaaaacgatctggcgttcgactgggaaaac
tacaccccgccggtggcgcatcgtctgggcgtgcaggaggtcgaagccagcatcgaaacg
ctgcgtaactacatcgactggaccccgttctttatgacctggtcgctggccgggaaatat
ccacgcattctggaagatgaggtggtaggcgttgaggcgaagcgcctgtttaacgatgcc
aacgacatgctggataaactgagcgcggaaaagtcgctgaatccgcgcggcgtggtgggg
ctgtttccggcaaaccgcgtgggcgatgatatcgaaatctatcgcgatgaaacgcgtact
cacgtgctgacagtcagtcatcatctgcgtcagcagactgaaaaagtcggttttgccaac
tactgcctgtctgacttcgtggcgccgaagctgtccggcaaagcggactacatcggtgcc
tttgcggtaaccggaggtctggaggaggatgcgctggcagaggcgtttgaagcccagcac
gatgattacaacaagatcatggtgaaagcgcttgctgaccgtctggcggaagccttcgcg
gaatacctgcatgagcgcgtgcgtaaggtctactggggctatgcggccaacgagaacctc
agtaatgaggagttgattcgcgaaaactaccaggggattcgtcctgcgccggggtatccg
gcttgtccggagcacactgagaaaggcaccatctggcagttgctggatgtggaaaaacat
accggtatgaagctcactgaatccttcgccatgtggcctggcgcatcggtctctggctgg
tacttcagccatccggacagcaagtactacgcggtcgcgcagattcagcgcgatcaggtg
gaggactatgctttccgtaaagggatgagcgtctctgaagttgaacgctggctggcccct
aacctgggctatgacgccgactaa

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