Cercocebus atys (sooty mangabey): 105577073
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Entry
105577073 CDS
T07242
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty00140
Steroid hormone biosynthesis
caty00980
Metabolism of xenobiotics by cytochrome P450
caty01100
Metabolic pathways
caty05204
Chemical carcinogenesis - DNA adducts
Module
caty_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
105577073 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
105577073 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
105577073 (HSD11B1)
Enzymes [BR:
caty01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
105577073 (HSD11B1)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
Pyr_redox_3
Pyr_redox_2
Shikimate_DH
NAD_binding_2
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
105577073
NCBI-ProteinID:
XP_011896240
Ensembl:
ENSCATG00000042915
LinkDB
All DBs
Position
Unknown
AA seq
315 aa
AA seq
DB search
MWALGNFVENQLAVGVFRPAPCRMAFMKKYLLPILGLFMAYYYYSAYEEFRPEMLQGKKV
IVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMT
FAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPM
LKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVAKVNVSITLCVLGL
IDTDTAMKAVSGIINMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLMRNPCRKILE
FLYLPSYNMDRLKKN
NT seq
948 nt
NT seq
+upstream
nt +downstream
nt
atgtgggctcttggcaactttgttgaaaatcagctggctgtaggagtcttcaggccagct
ccctgtcggatggcttttatgaaaaaatatctcctccccattctggggctcttcatggcc
tactactactattctgcatatgaggaattcagaccagagatgctccaaggaaagaaagtg
attgtcacaggggccagcaaagggatcggaagagagatggcttatcatctggcgaagatg
ggagcccacgtggtggtaacagcgaggtcaaaagaaactctacagaaggtggtttcccac
tgcctggaacttggagcagcctcagcacactacattgctggcaccatggaagacatgacc
ttcgcagagcaatttgttgcccaagcaggaaagctcatgggaggactagacatgctcatt
ctcaaccacatcaccaacacttctttgaatctttttcatgatgatattcaccatgtgcgc
aaaagcatggaggtcaacttcctcagttatgtggtcctgactgtagctgccttgcccatg
ctgaagcagagcaatggaagcattgttgtcgtctcttctttggctgggaaagtggcttat
ccaatggttgctgcctattctgcaagcaagtttgctttggatgggttcttctcctccatc
agaaaggaatattcagtggccaaggtcaatgtatcaatcactctctgtgttcttggcctc
atagacacagacacagccatgaaggcagtttctgggataatcaatatgcaagcagctcca
aaggaggaatgtgcccttgagatcatcaaagggggagctctgcgtcaagaagaagtatat
tatgacagctcactctggaccactcttctgatgagaaatccatgcaggaagatcctggaa
tttctctacttaccaagctataatatggacagattaaaaaaaaactag
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