Cercocebus atys (sooty mangabey): 105580035 Help Entry 105580035         CDS       T07242                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism caty  Cercocebus atys (sooty mangabey) Pathway caty01524   Platinum drug resistance caty04115   p53 signaling pathway caty04210   Apoptosis caty04215   Apoptosis - multiple species caty04217   Necroptosis caty04620   Toll-like receptor signaling pathway caty04621   NOD-like receptor signaling pathway caty04622   RIG-I-like receptor signaling pathway caty04623   Cytosolic DNA-sensing pathway caty04625   C-type lectin receptor signaling pathway caty04657   IL-17 signaling pathway caty04668   TNF signaling pathway caty04932   Non-alcoholic fatty liver disease caty04936   Alcoholic liver disease caty05010   Alzheimer disease caty05016   Huntington disease caty05022   Pathways of neurodegeneration - multiple diseases caty05132   Salmonella infection caty05134   Legionellosis caty05142   Chagas disease caty05145   Toxoplasmosis caty05152   Tuberculosis caty05160   Hepatitis C caty05161   Hepatitis B caty05162   Measles caty05163   Human cytomegalovirus infection caty05164   Influenza A caty05165   Human papillomavirus infection caty05167   Kaposi sarcoma-associated herpesvirus infection caty05168   Herpes simplex virus 1 infection caty05169   Epstein-Barr virus infection caty05170   Human immunodeficiency virus 1 infection caty05200   Pathways in cancer caty05203   Viral carcinogenesis caty05416   Viral myocarditis caty05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:caty00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     105580035 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     105580035 (CASP8)    04215 Apoptosis - multiple species     105580035 (CASP8)    04217 Necroptosis     105580035 (CASP8)    04115 p53 signaling pathway     105580035 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105580035 (CASP8)    04621 NOD-like receptor signaling pathway     105580035 (CASP8)    04622 RIG-I-like receptor signaling pathway     105580035 (CASP8)    04623 Cytosolic DNA-sensing pathway     105580035 (CASP8)    04625 C-type lectin receptor signaling pathway     105580035 (CASP8)    04657 IL-17 signaling pathway     105580035 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105580035 (CASP8)    05203 Viral carcinogenesis     105580035 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105580035 (CASP8)    05161 Hepatitis B     105580035 (CASP8)    05160 Hepatitis C     105580035 (CASP8)    05164 Influenza A     105580035 (CASP8)    05162 Measles     105580035 (CASP8)    05168 Herpes simplex virus 1 infection     105580035 (CASP8)    05163 Human cytomegalovirus infection     105580035 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     105580035 (CASP8)    05169 Epstein-Barr virus infection     105580035 (CASP8)    05165 Human papillomavirus infection     105580035 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     105580035 (CASP8)    05134 Legionellosis     105580035 (CASP8)    05152 Tuberculosis     105580035 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105580035 (CASP8)    05142 Chagas disease     105580035 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     105580035 (CASP8)    05016 Huntington disease     105580035 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     105580035 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105580035 (CASP8)    05416 Viral myocarditis     105580035 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105580035 (CASP8)    04932 Non-alcoholic fatty liver disease     105580035 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105580035 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:caty01002]     105580035 (CASP8) Enzymes [BR:caty01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      105580035 (CASP8) Peptidases and inhibitors [BR:caty01002]  Cysteine peptidases   Family C14: caspase family    105580035 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED DUF8196 Motif Other DBs NCBI-GeneID:  105580035 NCBI-ProteinID:  XP_011902895 Ensembl:  ENSCATG00000036996 UniProt:  A0A2K5MPT8 LinkDB All DBs Position Unknown AA seq 479 aa AA seqDB search MDFNRNLYDIGEQLDSEELASLKFLSLDCIPQRKREPIKDALMLFQRLQEKRMLEENNLS FLKELLFRINRLDLLTTYLNTRKEEMERELQAPGRAQISAYRVMLYQISEEVGRSELRSF KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQVNKSLLKIINDYEE FSRERTRSLEGSPEEGSNGEELCGLMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIIN NYDFTKAREKVPKLHSIRDRNGTHLDAEALTATFEELHFEIQHHNDCTVEKIYKILKTYQ LMDHSNKDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQAC QGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTW YIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggacttcaacagaaatctttatgatattggggaacaactggacagtgaagagctggcc tccctcaagttcctgagcctggactgcatcccacaaaggaagcgagaacccatcaaggat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaaacaatctgtcc ttcctgaaggagctgctcttccgaattaatagactggatttgctcactacttacctaaac actagaaaggaggagatggaaagggaacttcaggcaccaggcagggctcagatttctgcc tacagggtcatgctctatcagatttcagaagaggtgggcagatcagaattgaggtctttt aagtttcttctgcaagaggagatctccaaatgcaaactggatgatgacatgaacctgctg gatattttcatagagatggagaagagggtcatcctgggagaaggcaagttggacatcctg aagagagtctgtgcccaagtcaacaagagcctgctgaagataatcaatgactatgaagaa ttcagcagagagagaacaaggagccttgaaggaagtcctgaggaaggttcaaatggggag gagttgtgtgggctaatgacaatctcggactctccaagagaacaggatagtgaatcacag actttggacaaagtttaccaaatgaaaagcaaacctcggggatactgtctgatcatcaac aattacgattttacgaaagcacgggagaaagtgcccaaacttcacagcattagggacagg aatggaacacacttggatgcagaggctttgaccgcgacctttgaagagcttcattttgag atccagcaccacaatgactgcacagtagagaaaatctataagattttgaaaacctaccaa ctcatggaccacagtaacaaggattgcttcatctgctgtatcctctcccatggagacaag ggcatcatctatggcactgatggacaggaggcccccatctatgagctgacatctcagttc actggtttgaagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgt cagggggataactaccagaaaggtatacctgttgagactgattcagaggagcaaccctat ttggaaatggatttatcatcacctcaaacgagatatatcccagatgaggctgactttctg ctggggatggccactgtgaataactgtgtttcctaccgaaaccctgcagagggaacctgg tacatccagtcactttgccagagcctgagagaacgatgtcctcgaggcgatgatattctc accatcctgactgaagtgaactatgaagtaagcaacaaggatgacaagaaaaacatggga aaacagatgccacagccaactttcacactaagaaaaaaacttgtcttcccttctgattga

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