Cercocebus atys (sooty mangabey): 105584904 Help Entry 105584904         CDS       T07242                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism caty  Cercocebus atys (sooty mangabey) Pathway caty04022   cGMP-PKG signaling pathway caty04068   FoxO signaling pathway caty04081   Hormone signaling caty04140   Autophagy - animal caty04152   AMPK signaling pathway caty04211   Longevity regulating pathway caty04213   Longevity regulating pathway - multiple species caty04910   Insulin signaling pathway caty04920   Adipocytokine signaling pathway caty04923   Regulation of lipolysis in adipocytes caty04930   Type II diabetes mellitus caty04931   Insulin resistance caty04932   Non-alcoholic fatty liver disease caty04935   Growth hormone synthesis, secretion and action caty05010   Alzheimer disease caty05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:caty00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     105584904 (IRS2)    04022 cGMP-PKG signaling pathway     105584904 (IRS2)    04152 AMPK signaling pathway     105584904 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     105584904 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     105584904 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105584904 (IRS2)    04923 Regulation of lipolysis in adipocytes     105584904 (IRS2)    04920 Adipocytokine signaling pathway     105584904 (IRS2)    04935 Growth hormone synthesis, secretion and action     105584904 (IRS2)   09149 Aging    04211 Longevity regulating pathway     105584904 (IRS2)    04213 Longevity regulating pathway - multiple species     105584904 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     105584904 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     105584904 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105584904 (IRS2)    04932 Non-alcoholic fatty liver disease     105584904 (IRS2)    04931 Insulin resistance     105584904 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  105584904 NCBI-ProteinID:  XP_011913411 Ensembl:  ENSCATG00000037723 UniProt:  A0A2K5MUJ5 LinkDB All DBs Position Unknown AA seq 1338 aa AA seqDB search MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDEA TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAAAADAPPTAAPAASCSASLPGALGGSAGAAGA EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGGEFY GYMTMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAATVPPAGPAGPAPTSAAGRTF PASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLLNGDYLNVSPSDAVTTGTP PDFFSAALHAGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLE PQATPGPSQAASAFGTGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPS LPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGS GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGARSGHPVGSLDALLSPEASSPYPPLPPR PSASPSSSSLQPPPPPPPPGELYRLPPASAAATVQGPGAASSSDTGDNGDYTEMAFGVAA TPPQPIAAPAKPEAVRVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQ GGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGGVPGGGDEPP TSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREE PGLPPQPQPQPQSPLPQPGDKNSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTY ASIDFLSHHLKEATIVKE NT seq 4017 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgcggcacgggccgcccgggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcacgggcggcgacgaggcg acggcgggaggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa aagtggcggagcaaggcaggcgcgccgaagcgggtgatcgcgctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcggccgccgcagacgcgccccccaccgccgcgcccgcc gcgtcctgcagcgcctccctgcccggcgccctgggcggctctgccggcgccgccggggcc gaggacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtg aacctgaagcccaagggtctgggccagagcaagaacctgacgggcgtgtaccgtctgtgc ctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctg cagctcatgaacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggc cgctcggccgtcacgggtcccggcgagctgtggatgcaggcggatgactcggtggtggcg cagaacatacacgagaccatcctggaggccatgaaggcgctcaaagagctcttcgagttc cggccacgcagcaagagccagtcgtcggggtcgtcggccacacaccctatcagcgtcccc ggcgcgcgccgccaccaccacctggtcaacctaccccccagccagacgggcttggtgcgc cgttcgcgcaccgacagcctggccgccaccccgccggcggccaagtgcagctcgtgccgg gtgcgcaccgccagcgagggcgacggcggcgcggcggcgggggcagcggccgcgggcgcc aggccagtgtcggtggctgggagccccttgagccccgggccggtgcgcgcgcccctgagc cgctcgcacaccctgagcggcggctgcggcggccgcgggagcaaggtggcgctgctgccg gcagggggcgcgctgcagcacagccgctccatgtccatgcctgtggcgcactcgccgccc gccgccaccagccccggctccctgtcgtccagcagcggccacggctcgggctcctacccg ccgccgccgggcccgcacccgcccctgccgcacccactgcaccacggccccggccagcgg ccctccagcggcagcgcctccgcctcgggctcccccagcgaccccggcttcatgtccctg gacgagtacggctccagccccggcgacctgcgcgccttctgcagccaccggagcaacacg cccgagtccatcgcggaaacgccccctgcgcgagacggcagcggcggcggtgagttctac gggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgcagggtctcg ggagacgcggcccaggacctggaccgagggctgcgcaagaggacctactccctgaccacg ccggcccggcagcggccggtgccccagccctcctccgcctcgctggatgagtacaccctg atgcgggccaccttctccggcagcgcaggccgcctctgcccgtcctgccccgcgtcctct cccaaggtggcctaccacccctacccagaggactacggagatatcgagatcggctcccac aggagctccagcagcaacctgggtgcagacgacggctacatgcccatgacgcctggcgcg gccctcgcgggcagtgggagcggcagctgcaggagcgacgactacatgcccatgagccct gccagcgtgtccgcccccaagcagatcttgcagcccagggccgccgccgctgccgccgcc accgtgccccctgcggggcctgcggggccagcgcccacctctgcggcgggcaggacattc ccggcgagcgggggcggttacaaggccagctcgccggccgagagctctcccgaggacagc gggtacatgcgcatgtggtgcggctccaagctgtccatggagcacgcggacggcaagctg ctgctcaacggggactacctcaacgtgtcccccagcgacgcggtcaccaccggcaccccg cccgacttcttctccgcagccctgcacgccggcggggagccgctcaggggcgttcctggc tgctgctacagctccttgccccgctcctacaaggccccctacacctgcggtggggacagc gaccagtacgtgctcatgagctcccccgtggggcgcatcctggaggaagagcggctggag cctcaggccacgccagggcccagccaggcggccagcgccttcgggacaggccccacgcag ccccctcaccccgtagtgccttcgcccgtgcgacccagtggcggccgccccgagggtttc ctgggccagcgcggccgggctgtgcggcccacacgcctgtccctggaggggctgcccagc ctgcccagcatgcacgagtacccactgccgccagagcccaagagccccggcgagtacatc aacatcgactttggcgagcccggggcccgcctgtcgccgcccgcgcctcccctgctggcg tcggcggcctcgtcctcctcgctcttgtccgccagcagcccggcctcgtcgttgggctca ggcaccccgggcaccagcagcgacagccggcagcgctccccgctctctgactacatgaac ctcgacttcagctcccccaagtctcccaagccgggcgcccggagcggccaccccgtgggc tccttggacgccctcctgtcccctgaggcctcctccccgtatccgccgctgcccccgcgt ccgtccgcatccccgtcgtcgtcgtccctgcagccgccaccgccaccaccgccccccggg gagctgtaccgcttgccccctgcttcggccgctgccaccgtccagggcccaggcgccgcc tcgtcctcggacaccggagacaatggtgactacaccgagatggctttcggtgtggccgcc accccgccgcaacccatcgcggcccccgcgaagccagaagctgtccgcgtggccagcccg acgtcgggcgtgaagaggctgagcctcatggagcaggtgtcgggggtcgaggccttcctg caggccagccagcccccggacccccaccgcggcgccaaggtcatccgcgcagacccacag gggggccgccgccgccacagctccgagaccttctcctccaccacgacggtcacccccgtg tccccgtctttcgcccacaaccccaagcgccacaactcggcctccgtggaaaatgtgtct ctcaggaaaagcagcgagggcggcgtgggcggcgtccctggagggggcgacgagccgccc acctcccccagacagttgcagccggcgccccccttggcaccgcagggccggccttggacc ccgggtcagcccgggggcttggtcggttgtcctgggagcggtggatcaccaatgcgcaga gagacctctgccggcttccagaatggtctcaactacatcgccatcgacgtgagggaggag cccgggctgccaccccagccgcagccgcagccgcagtcgccgcttcctcagccgggagac aagaactcctggggtcggacccgaagcctcgggggtctcatcagcgctgtgggcgtcggc agcaccggtggcgggtgcggggggccaggtcccggggccctgccccctgccaacacctac gctagcattgacttcttgtcccaccacttgaaggaggccaccatcgtgaaagagtga

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