KEGG   Cercocebus atys (sooty mangabey): 105587240
Entry
105587240         CDS       T07242                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
caty  Cercocebus atys (sooty mangabey)
Pathway
caty01522  Endocrine resistance
caty04110  Cell cycle
caty04115  p53 signaling pathway
caty04151  PI3K-Akt signaling pathway
caty04218  Cellular senescence
caty04530  Tight junction
caty04660  T cell receptor signaling pathway
caty04933  AGE-RAGE signaling pathway in diabetic complications
caty04934  Cushing syndrome
caty05160  Hepatitis C
caty05162  Measles
caty05163  Human cytomegalovirus infection
caty05164  Influenza A
caty05165  Human papillomavirus infection
caty05166  Human T-cell leukemia virus 1 infection
caty05167  Kaposi sarcoma-associated herpesvirus infection
caty05169  Epstein-Barr virus infection
caty05200  Pathways in cancer
caty05203  Viral carcinogenesis
caty05212  Pancreatic cancer
caty05214  Glioma
caty05218  Melanoma
caty05219  Bladder cancer
caty05220  Chronic myeloid leukemia
caty05222  Small cell lung cancer
caty05223  Non-small cell lung cancer
caty05224  Breast cancer
caty05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:caty00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    105587240 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    105587240 (CDK4)
   04115 p53 signaling pathway
    105587240 (CDK4)
   04218 Cellular senescence
    105587240 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105587240 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    105587240 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105587240 (CDK4)
   05203 Viral carcinogenesis
    105587240 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    105587240 (CDK4)
   05225 Hepatocellular carcinoma
    105587240 (CDK4)
   05214 Glioma
    105587240 (CDK4)
   05220 Chronic myeloid leukemia
    105587240 (CDK4)
   05218 Melanoma
    105587240 (CDK4)
   05219 Bladder cancer
    105587240 (CDK4)
   05224 Breast cancer
    105587240 (CDK4)
   05222 Small cell lung cancer
    105587240 (CDK4)
   05223 Non-small cell lung cancer
    105587240 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105587240 (CDK4)
   05160 Hepatitis C
    105587240 (CDK4)
   05164 Influenza A
    105587240 (CDK4)
   05162 Measles
    105587240 (CDK4)
   05163 Human cytomegalovirus infection
    105587240 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105587240 (CDK4)
   05169 Epstein-Barr virus infection
    105587240 (CDK4)
   05165 Human papillomavirus infection
    105587240 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105587240 (CDK4)
   04934 Cushing syndrome
    105587240 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105587240 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:caty01001]
    105587240 (CDK4)
Enzymes [BR:caty01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     105587240 (CDK4)
Protein kinases [BR:caty01001]
 Serine/threonine kinases: CMGC group
  CDK family
   105587240 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 105587240
NCBI-ProteinID: XP_011918652
Ensembl: ENSCATG00000017600
UniProt: A0A2K5KXC2
LinkDB
Position
Unknown
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgggaggtggccttactg
aggcgactggaggcttttgaacatcccaatgtagtccggctgatggacgtctgtgccact
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaagaccta
aggacgtatctggacaaagcacccccaccaggcttgccagccgagaccatcaaggatttg
atgcgccagtttctaagaggcctagatttccttcatgcaaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacccgtggttgttacactctggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggagtcgggagcacagctgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga

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