Cercocebus atys (sooty mangabey): 105588320 Help Entry 105588320         CDS       T07242                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism caty  Cercocebus atys (sooty mangabey) Pathway caty00230   Purine metabolism caty01100   Metabolic pathways caty01522   Endocrine resistance caty04015   Rap1 signaling pathway caty04020   Calcium signaling pathway caty04022   cGMP-PKG signaling pathway caty04024   cAMP signaling pathway caty04062   Chemokine signaling pathway caty04072   Phospholipase D signaling pathway caty04081   Hormone signaling caty04082   Neuroactive ligand signaling caty04114   Oocyte meiosis caty04211   Longevity regulating pathway caty04213   Longevity regulating pathway - multiple species caty04261   Adrenergic signaling in cardiomyocytes caty04270   Vascular smooth muscle contraction caty04371   Apelin signaling pathway caty04540   Gap junction caty04611   Platelet activation caty04713   Circadian entrainment caty04714   Thermogenesis caty04720   Long-term potentiation caty04723   Retrograde endocannabinoid signaling caty04724   Glutamatergic synapse caty04725   Cholinergic synapse caty04727   GABAergic synapse caty04750   Inflammatory mediator regulation of TRP channels caty04911   Insulin secretion caty04912   GnRH signaling pathway caty04913   Ovarian steroidogenesis caty04914   Progesterone-mediated oocyte maturation caty04915   Estrogen signaling pathway caty04916   Melanogenesis caty04918   Thyroid hormone synthesis caty04921   Oxytocin signaling pathway caty04923   Regulation of lipolysis in adipocytes caty04925   Aldosterone synthesis and secretion caty04926   Relaxin signaling pathway caty04927   Cortisol synthesis and secretion caty04928   Parathyroid hormone synthesis, secretion and action caty04934   Cushing syndrome caty04935   Growth hormone synthesis, secretion and action caty04970   Salivary secretion caty04971   Gastric acid secretion caty04972   Pancreatic secretion caty04976   Bile secretion caty05032   Morphine addiction caty05142   Chagas disease caty05146   Amoebiasis caty05163   Human cytomegalovirus infection caty05166   Human T-cell leukemia virus 1 infection caty05200   Pathways in cancer caty05207   Chemical carcinogenesis - receptor activation caty05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:caty00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105588320 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105588320 (ADCY1)    04371 Apelin signaling pathway     105588320 (ADCY1)    04020 Calcium signaling pathway     105588320 (ADCY1)    04072 Phospholipase D signaling pathway     105588320 (ADCY1)    04024 cAMP signaling pathway     105588320 (ADCY1)    04022 cGMP-PKG signaling pathway     105588320 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105588320 (ADCY1)    04081 Hormone signaling     105588320 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105588320 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     105588320 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105588320 (ADCY1)    04062 Chemokine signaling pathway     105588320 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     105588320 (ADCY1)    04923 Regulation of lipolysis in adipocytes     105588320 (ADCY1)    04912 GnRH signaling pathway     105588320 (ADCY1)    04913 Ovarian steroidogenesis     105588320 (ADCY1)    04915 Estrogen signaling pathway     105588320 (ADCY1)    04914 Progesterone-mediated oocyte maturation     105588320 (ADCY1)    04921 Oxytocin signaling pathway     105588320 (ADCY1)    04926 Relaxin signaling pathway     105588320 (ADCY1)    04935 Growth hormone synthesis, secretion and action     105588320 (ADCY1)    04918 Thyroid hormone synthesis     105588320 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     105588320 (ADCY1)    04916 Melanogenesis     105588320 (ADCY1)    04925 Aldosterone synthesis and secretion     105588320 (ADCY1)    04927 Cortisol synthesis and secretion     105588320 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105588320 (ADCY1)    04270 Vascular smooth muscle contraction     105588320 (ADCY1)   09154 Digestive system    04970 Salivary secretion     105588320 (ADCY1)    04971 Gastric acid secretion     105588320 (ADCY1)    04972 Pancreatic secretion     105588320 (ADCY1)    04976 Bile secretion     105588320 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     105588320 (ADCY1)    04727 GABAergic synapse     105588320 (ADCY1)    04725 Cholinergic synapse     105588320 (ADCY1)    04720 Long-term potentiation     105588320 (ADCY1)    04723 Retrograde endocannabinoid signaling     105588320 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     105588320 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     105588320 (ADCY1)    04213 Longevity regulating pathway - multiple species     105588320 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     105588320 (ADCY1)    04714 Thermogenesis     105588320 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105588320 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     105588320 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105588320 (ADCY1)    05163 Human cytomegalovirus infection     105588320 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     105588320 (ADCY1)    05142 Chagas disease     105588320 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     105588320 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105588320 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105588320 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105588320 (ADCY1) Enzymes [BR:caty01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105588320 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA DUF6594 Motif Other DBs NCBI-GeneID:  105588320 NCBI-ProteinID:  XP_011920917 Ensembl:  ENSCATG00000004075 LinkDB All DBs Position Unknown AA seq 894 aa AA seqDB search MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPDRIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSF LKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADL NFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVAVLLLLVFCI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNS SLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYIL VLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEERED MEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELD GNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSIS SHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNV ASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQI RSLGLDRKMGPYGRAGLQGRRPPVCPMPGVSVRAGLPPHSPGQYLSSAAAGKEA NT seq 2685 nt NT seq  +upstreamnt  +downstreamnt atgtatggggtcttcgtgcggattctgactgagcgttcgcagaggaaggcgttcctgcag gcccggagctgcattgaggaccgactgaggctggaggatgagaacgagaagcaggagcgg ctcctcatgagcctcctgccccggaacgttgccatggagatgaaggaggacttcctgaag ccccctgacaggattttccacaagatttacatccagaggcacgacaatgtgagcatcctg tttgctgacatcgtgggtttcacgggcttggcatcccagtgcacggcccaggagctggtg aaactcctcaatgagctcttcggcaagtttgacgaattagccacggagaaccactgtcgt cgcatcaagattctcggggactgctactactgcgtgtcgggactgacccagcccaagact gaccatgcccactgctgcgtggagatggggctcgacatgattgataccatcacatccgtg gctgaagccaccgaggtggacctgaacatgcgtgtgggtttgcacacgggcagggtcctc tgtggtgtcctgggcttgcgcaagtggcagtatgacgtgtggtccaatgatgtgaccttg gccaatgtcatggaagccgctggcctgccagggaaggttcatatcacaaagacgacccta gcgtgcttgaatggggactacgaggtagaaccaggttacggacatgagaggaacagtttc ttgaaaactcataacattgaaaccttttttattgtgccatcccatcgccgaaagatattt ccaggcctgattctctcagatataaaaccggccaagaggatgaagttcaagactgtctgc tacctgctggtgcagctcatgcactgccgaaagatgttcaaggccgagatccccttctcc aatgtcatgacctgcgaggacgatgacaagcggagggcgttgagaacagcctcagaaaaa ctcagaaaccgctcatctttttctaccaacgttgtctacaccaccccgggcactcgtgtc aacaggtacatcagccgcctcttagaagcccgccagacagagctggagatggcagacctg aacttctttaccctgaagtacaaacatgttgaacgggagcaaaagtaccaccagcttcag gacgagtatttcaccagcgctgttgtcctcaccctcatcctggctgccttatttggcctt gtctaccttctaatattcccacagagtgtggccgtcctgctcctgctagtattctgcatc tgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtccagtgttttccaggg tgcctgacgattcagattcgcactgtcctgtgtattttcatagtggtcttaatctactca gtagcccaaggatgtgtggtgggctgcctgccctgggcctggagctccaagcccaacagt tccctggtggtcctttcatccggaggccagcgcacagccctgcccaccctgccctgcgag tctacgcaccatgccctgctctgctgcctggtgggcaccctcccgctagccatatttttt cgggtgtcctccttgccaaaaatgatcctgctgtccgggctcaccacgtcctacatcctc gtactggagctcagtggatacaccaggactgggggtggtgccgtctccgggcgcagctat gagccgattgtggccatcctgctcttctcctgtgcgctggccctgcatgccaggcaggtg gacatcaggctgaggctggactacctctgggccgcacaggcagaggaggagcgagaggac atggagaaggtgaagctggacaacaggcgcatcctcttcaacctcctgccagcccacgtc gcccagcacttcctcatgtccaaccctcggaacatggacctctactaccagtcctactcc caggtgggcgtcatgtttgcctccatccccaactttaatgacttctatattgagctggac ggcaacaacatgggggtggagtgtctgcggcttctcaacgagatcattgccgactttgac gagctcatggaaaaagacttttacaaggatatagagaagatcaagaccattgggagcacc tacatggctgctgtggggctagcgcctacctcggggaccaaggctaagaagtccatctcc tcccacctgagcacgctggcagactttgccattgagatgtttgacgttctggatgaaatc aactaccagtcttacaacgactttgtcctccgagttggcatcaatgttggccccgtggtg gctggagtgattggcgctcgcaggccccagtacgacatctggggaaacacagtcaacgtg gccagtcggatggacagcacaggggtccagggcagaatccaggtgactgaggaagtccac cggctgctgagaagatgcccctaccactttgtgtgccgaggcaaagtcagtgtcaagggc aaaggcgagatgttgacatactttctagaaggcagaactgatggaaacggctcccaaatc aggtccctgggcttggatcggaaaatgggtccatatgggagagctggccttcagggcaga cgtcccccggtgtgccccatgcctggcgtctcagtcagggctgggctccctccacactcc ccaggccagtatctgtcctctgcagcagctgggaaggaggcttag

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