KEGG   Camelus bactrianus (Bactrian camel): 105080080
Entry
105080080         CDS       T07534                                 
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
  KO
K10605  breast cancer type 1 susceptibility protein [EC:2.3.2.27]
Organism
cbai  Camelus bactrianus (Bactrian camel)
Pathway
cbai01524  Platinum drug resistance
cbai03440  Homologous recombination
cbai03460  Fanconi anemia pathway
cbai04120  Ubiquitin mediated proteolysis
cbai04151  PI3K-Akt signaling pathway
cbai05206  MicroRNAs in cancer
cbai05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:cbai00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    105080080 (BRCA1)
  09124 Replication and repair
   03440 Homologous recombination
    105080080 (BRCA1)
   03460 Fanconi anemia pathway
    105080080 (BRCA1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    105080080 (BRCA1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    105080080 (BRCA1)
  09162 Cancer: specific types
   05224 Breast cancer
    105080080 (BRCA1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    105080080 (BRCA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:cbai01009]
    105080080 (BRCA1)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:cbai04121]
    105080080 (BRCA1)
   03036 Chromosome and associated proteins [BR:cbai03036]
    105080080 (BRCA1)
   03400 DNA repair and recombination proteins [BR:cbai03400]
    105080080 (BRCA1)
Enzymes [BR:cbai01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     105080080 (BRCA1)
Protein phosphatases and associated proteins [BR:cbai01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     105080080 (BRCA1)
Ubiquitin system [BR:cbai04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    105080080 (BRCA1)
  Multi subunit type E3
   BRCC complex
    105080080 (BRCA1)
Chromosome and associated proteins [BR:cbai03036]
 Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     105080080 (BRCA1)
DNA repair and recombination proteins [BR:cbai03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    BRCA1-core complex
     105080080 (BRCA1)
    BRCA1-A complex
     105080080 (BRCA1)
    BRCA1-B complex
     105080080 (BRCA1)
    BRCA1-C complex
     105080080 (BRCA1)
    BRCA complex
     105080080 (BRCA1)
   FA (Fanconi anemia) pathway
    Downstream FA components
     105080080 (BRCA1)
SSDB
Motif
Pfam: BRCT_assoc BRCT zf-C3HC4 zf-C3HC4_2 zf-RING_UBOX zf-C3HC4_4 zf-RING_2 zf-C3HC4_3 zf-RING_5 RING_XB3-XBAT31 BRCT_2 zf-RING_6 zf-Nse zf-RING_10 zf-ANAPC11 zf-rbx1 RTT107_BRCT_5 Baculo_IE-1 Prok-RING_4
Other DBs
NCBI-GeneID: 105080080
NCBI-ProteinID: XP_010967239
UniProt: A0A9W3H2D1
LinkDB
Position
Unknown
AA seq 1859 aa
MDLSADRIEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQENTRFSQLVEELLKIIHAFELDTGLQFANSYNFSKKQNISPEHIKE
EVSIIQSMGYRNRAKRLQQSESENPSLQETSLGIQLSNLGIVRSLRTKQQTQPQNKSVYI
ELGSDSSEDTVNKASYCSVGDHKLLEITPQGTKAETSVNPAEKAACEFSEDITNTEHHRS
SNKDLTTTEKHETEKHPEKYQGISVSNLHVEPCGTDTHASSLQHENSSLLLTKDRINVEK
AEFCNKSKQPVLARSQQSRWAESKDTCNDRQTPSTEKKVVLNADRLYGSEELNEQKPACS
DSPRDSQDVPWITLNSSIQKVNEWFSRSDKMLPSDDSHEVGPESNTEVAGAVEVPNEVDG
YSGSSEKIDLMASDPHGALKCENEKVHTKPVGSNIEDKIFGKTYRRKASLPNLTHRAEDL
ILGASVLEPQITQERPFTNKLKRKRRTLPGLHPEDFIKKVDLAVVQKAPEKIIERTDQTE
QNGHGMNITSNGHENETNDDYVQKEKNANPTESLGKESAFKTKAEPISSSISNMELELNT
HSSKAPKNRPRRKSSTRQIHALELIVNRNPSPPNHTELQIESCSSSEEMKEKHSDQMPVR
HRKKLQLTGDKEPTTGTKKSNKPHQQINKRLVGNTFPELNLTNTPGFFTNCSSSNKLQEF
ANPSLQREENPGAIQVSNSTKDPKVLILSGGRGLQIERSVENTSISLVPETDYDTQDSVS
LLEADTLGKAKTAPNQCVSLCATTENSKELIHSCSKDTRNATAGFKDPLGCDINHTQEAS
MEVEESELDTQYLQNTFKVSKRQTFALFSNPGDSEKECATVYAHSGPLREQSPRITLECG
QKEENQRKSKSEIKHMQADHTTLNFPVVGQKDKPSDYAKYSPKGISRLCWPSQLRDNESE
FIIANKHGILQNPYLITSLSPNRSSVKTMCKKNPSEEKLEKCVISPKRVMGNESTIQSTV
SAMSQNNIRESTFKEVSSSSVNEVGSSTNEVGSSINEVGSSGENIQAELGRNMGPKLNAM
LRLGLLQPEVCEQSLPVSNCKQPEIKRQGENEGIFQAVNANFSPCLISDNLEQPMGSSHA
SQVCSETPDDLLYDDEIKENTSFAESDIKERSAVFSKSVQKEFRRSPSPLVHTHLAQGHQ
RGAGKLESSEENVSSEDEELPCFQHLLFGKVTNTPSQSARHNTIATGSLSKETEENLVSL
KTSLNDCSDQVTSAKASQERHLSEDARCSSSLFSSQCSVLEDLTVNTNSQDPFLMFDPPS
KQAEHQSENQEVLSDKELVSDDDEREASLEEDYCQEEQSVDSDLGEAASGYASETSFSED
CSGLSSQSGILTTQQRDTMQDNLIKLQQEMAELEAVLEQHGSQPSRSSPSLVADSCAPKD
LLNPEQNTSEKAVLTSEKSSEYPISQNPESLSADKFKGSLDSSTSKNEEPGRERSSPSRS
QSSDNRWYTHSHSRSLQSRNCQSQKELIKVVDVEEQQLTKSEAQDLMERSYMPGQDLEGT
PYLKSGISLFSDDPASNPSEDRAPNVCSMPSSTSALKLPQFQVEESAESPAAAHTTKTAG
CNVREESVSREKPEVVSSPKRGNKRISMVASGLTPKELMLVQKFARKHHITVTNLVTEET
THVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGR
NHQGPKRARESQDRKIFKGLEICCYGPFTNMPTDQLEWMVHLCGASVVKEPSSFTRSEGT
HSIVVVQPDAWTEDSGFHVIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQLPHSCC
NT seq 5580 nt   +upstreamnt  +downstreamnt
atggatttatctgcagatcgcattgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagaacctgtttccacaaagtgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatataaccaaaagaagcttacaagaaaatacaagatttagt
cagcttgttgaagagctgttgaagatcattcatgcttttgagcttgacacaggattgcag
tttgcaaatagttacaacttttcaaaaaaacaaaatatctctcctgaacatataaaggag
gaagtttctatcatccaaagtatgggctatcgaaaccgggccaaaagacttcaacagagt
gaatctgaaaatcctagcttgcaggaaaccagtcttggtatccaactctctaaccttgga
attgtgagatctctgaggacaaagcagcagacacagcctcagaataagtctgtctacatt
gagctgggatctgattcttctgaagatacagttaataaggcaagttattgcagtgtggga
gaccacaaattattagaaatcacccctcaaggaaccaaggctgaaaccagtgtgaatcct
gcagaaaaggctgcttgtgaattttctgaggacataacaaatactgaacatcatcgatcc
agtaacaaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaagtat
cagggtatttctgtttcaaacttgcatgtggagccgtgtggcacagatactcatgccagc
tcattacagcatgagaacagcagtttattactcactaaggacagaataaatgtagaaaag
gctgaattctgtaataaaagcaaacagcctgtcttagcaaggagccaacagagcagatgg
gctgaaagtaaggacacatgtaatgataggcagactcccagcacagagaaaaaggtggtt
ctgaatgccgatcgcttatatgggagcgaagaactgaatgagcagaaacctgcatgctct
gacagtcctagagattcccaagatgttccttggataacactgaatagtagcatacagaaa
gtgaatgagtggttttccagaagtgacaaaatgttaccttctgatgactcacatgaagtg
gggcctgaatcaaatactgaagtagctggtgcagtggaagttccaaatgaagtagatggc
tattcaggctcttcagagaaaatagacttaatggccagtgatcctcatggtgctttaaaa
tgtgaaaatgaaaaagtccacaccaaaccagtagggagtaatattgaagataaaatattt
gggaaaacctatcggaggaaggcaagcctccctaacttgacccacagagctgaagatcta
attctaggagcatctgttctagagcctcagataacacaagagcgccccttcacaaataaa
ctaaagcgtaaaaggagaactctaccaggtcttcatcctgaggattttatcaagaaagtc
gatttggccgttgttcaaaaggctcctgaaaagataattgagcgaacagaccaaacagag
cagaatggtcatgggatgaatattactagtaatggtcatgagaatgaaacaaacgacgat
tacgttcagaaagagaaaaatgctaacccaacagaatcattgggaaaagaatctgctttc
aaaactaaggctgaacctataagcagcagtataagcaatatggaactagaattgaatacc
catagttcaaaagcacctaagaataggccgaggaggaagtcctctaccaggcagattcat
gcacttgaactaatagtcaatagaaacccaagcccacctaatcacactgaactacagatt
gagagttgttccagcagtgaagagatgaaggaaaaacattctgaccaaatgccagtcagg
caccgcaaaaagcttcagctcacgggagataaagaacctacaactggaaccaagaagagt
aacaagccacatcaacaaataaataaaagacttgtcggtaacacttttccagaactaaat
ttaacaaacacacctggtttttttactaactgttcaagttctaataaacttcaagagttt
gccaatcctagccttcaaagagaagagaacccaggagcaattcaagtatcgaacagtacc
aaagaccccaaagttctgatattaagtggagggagaggtttacaaattgaaagatctgta
gagaataccagtatttccttggtacctgaaactgattatgacactcaggacagtgtctca
ttactggaagctgacaccctagggaaggcaaaaacagcaccaaatcaatgtgtgagtctc
tgtgcaacaactgaaaactccaaggaacttatccatagttgttctaaagatactagaaat
gccacagcaggctttaaggatccattgggatgtgacattaatcacactcaggaggcaagc
atggaagtggaagagagtgaacttgatacacagtatttgcagaatacgttcaaggtttca
aagcgtcagacatttgctctgttttcaaatccaggagattcagaaaaggaatgtgcaaca
gtctatgcccactctgggcccttaagggaacaaagtccaagaatcactcttgaatgtgga
caaaaagaagaaaatcagagaaagagcaagtctgaaatcaagcatatgcaggcagatcat
acaactttgaactttcctgtggttggtcaaaaagataagccgagtgattatgccaaatat
agcccaaaaggaatatctaggctttgttggccatcacagctcagagacaatgaatctgag
ttcattattgcaaataaacatgggattttacaaaacccatatcttataacatcactttct
cctaacaggtcatctgttaaaactatgtgtaagaaaaacccatccgaggaaaagcttgag
aaatgtgtcatatcacctaagagagtgatgggaaacgagagcaccattcaaagtacagtg
agcgcaatgagccaaaataacattagagaaagcacttttaaagaagtcagctcaagcagt
gtcaatgaagtaggttccagtactaatgaagtaggttctagtattaatgaagtaggttcc
agtggtgaaaacattcaagcagaactaggtagaaacatgggtcctaaattaaatgctatg
ctcagattaggtcttttgcaacctgaagtctgtgagcaaagtcttcctgtaagtaattgt
aaacaacctgaaataaaaaggcaaggagaaaatgaaggcatctttcaggctgttaatgcc
aacttctctccatgtctaatttcagataacctagaacaacctatgggaagcagtcatgct
tctcaggtttgttctgagacacctgatgacttgttatatgatgacgaaataaaggaaaat
accagctttgctgaaagtgacattaaggaaagatctgctgtttttagcaaaagtgtccaa
aaagaatttagaaggagccctagccctttagtgcatacgcatttggctcagggtcaccaa
agaggggctgggaaattagagtcctcagaagagaatgtgtctagtgaggatgaagagctt
ccatgcttccaacacttactgtttggtaaagtaaccaatacaccttctcaatctgccaga
cataacactattgccacagggagtctatctaaggaaacagaggagaacctagtatcattg
aagactagcttaaacgactgcagcgaccaggtaacgtctgcaaaggcgtctcaggaacgt
caccttagtgaggatgcgagatgttctagtagcctattttcttcacagtgcagtgtattg
gaagacttgactgttaatacaaacagccaggatcctttcttgatgtttgaccctccttcc
aaacaagctgagcatcagtctgaaaaccaggaagttctgagtgacaaggagctggtttca
gatgatgacgaaagggaagctagcctggaagaggattactgccaagaagagcagagtgtg
gattcagacttaggtgaagcagcatccgggtatgcaagtgaaacaagcttctctgaagat
tgttcagggctgtcttctcagagcggtatcttaaccactcagcagagggataccatgcaa
gataacctgataaagctccagcaagaaatggccgaactggaagctgtgttggagcagcac
gggagccagccttctcgcagctccccctcccttgtagccgattcttgtgcccctaaagac
ctgctaaatccggaacaaaacacatcagaaaaagcagtattaacttcagagaaaagtagt
gaatatcctataagccagaatccagaaagcctttctgctgacaagtttaaaggatctctg
gatagttccaccagtaaaaatgaagaaccaggaagggaaaggtcttccccttctagatcc
cagtcatcagataataggtggtatactcacagccactcaaggagtcttcagagcagaaac
tgccagtctcagaaggagctcattaaggttgttgacgtggaagagcaacagctgactaag
tctgaggcccaagatttaatggagcggtcttatatgccaggacaagatctagagggaacc
ccttacctaaaatctggaatcagcctcttctctgatgatcctgcgtctaatccctctgaa
gacagagccccaaacgtttgcagcatgccatcgtcaacctctgcattgaaattaccccaa
tttcaagttgaagaatctgccgagagtccagctgctgctcatactactaagactgctggg
tgtaatgtgagggaagaaagtgtgagcagggaaaagccagaagtggtatcttcaccaaaa
agaggcaacaaaagaatatctatggtggcatcaggcttgaccccaaaagaacttatgctt
gtgcagaagtttgccagaaaacatcacatcactgtaactaatctagtaactgaagagact
actcatgtcattatgaaaacagacgctgagtttgtgtgtgaacggaccctgaaatatttt
ctgggaattgcaggaggaaaatgggtagttagctatttttgggtgacccagtctattaaa
gaaagaaagatgctggatgagcatgactttgaagtcagaggagatgttgtcaatggaaga
aaccaccaaggtccaaagcgagcaagagaatcccaggacagaaagatctttaaaggccta
gaaatctgttgctatggaccctttaccaacatgcccacagatcaactagaatggatggtg
cacctctgtggggcttctgtggtgaaggagccctcatcattcacccgcagtgagggtact
cattcaattgtggtcgtgcagccggacgcctggacagaggacagtggcttccatgtgatt
gggcagatgtgtgaagcgcccgtggtgacccgagagtgggtattggacagcgtagccctc
taccagtgccaggagctggacacctacctgataccccagctcccccacagctgctgctga

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