KEGG   Camelus bactrianus (Bactrian camel): 105082679
Entry
105082679         CDS       T07534                                 
Symbol
PIK3R2
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit beta
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
cbai  Camelus bactrianus (Bactrian camel)
Pathway
cbai01521  EGFR tyrosine kinase inhibitor resistance
cbai01522  Endocrine resistance
cbai01524  Platinum drug resistance
cbai04012  ErbB signaling pathway
cbai04014  Ras signaling pathway
cbai04015  Rap1 signaling pathway
cbai04024  cAMP signaling pathway
cbai04062  Chemokine signaling pathway
cbai04066  HIF-1 signaling pathway
cbai04068  FoxO signaling pathway
cbai04070  Phosphatidylinositol signaling system
cbai04071  Sphingolipid signaling pathway
cbai04072  Phospholipase D signaling pathway
cbai04081  Hormone signaling
cbai04140  Autophagy - animal
cbai04150  mTOR signaling pathway
cbai04151  PI3K-Akt signaling pathway
cbai04152  AMPK signaling pathway
cbai04210  Apoptosis
cbai04211  Longevity regulating pathway
cbai04213  Longevity regulating pathway - multiple species
cbai04218  Cellular senescence
cbai04360  Axon guidance
cbai04370  VEGF signaling pathway
cbai04380  Osteoclast differentiation
cbai04510  Focal adhesion
cbai04550  Signaling pathways regulating pluripotency of stem cells
cbai04611  Platelet activation
cbai04613  Neutrophil extracellular trap formation
cbai04620  Toll-like receptor signaling pathway
cbai04625  C-type lectin receptor signaling pathway
cbai04630  JAK-STAT signaling pathway
cbai04650  Natural killer cell mediated cytotoxicity
cbai04660  T cell receptor signaling pathway
cbai04662  B cell receptor signaling pathway
cbai04664  Fc epsilon RI signaling pathway
cbai04666  Fc gamma R-mediated phagocytosis
cbai04668  TNF signaling pathway
cbai04670  Leukocyte transendothelial migration
cbai04722  Neurotrophin signaling pathway
cbai04725  Cholinergic synapse
cbai04750  Inflammatory mediator regulation of TRP channels
cbai04810  Regulation of actin cytoskeleton
cbai04910  Insulin signaling pathway
cbai04914  Progesterone-mediated oocyte maturation
cbai04915  Estrogen signaling pathway
cbai04917  Prolactin signaling pathway
cbai04919  Thyroid hormone signaling pathway
cbai04923  Regulation of lipolysis in adipocytes
cbai04926  Relaxin signaling pathway
cbai04929  GnRH secretion
cbai04930  Type II diabetes mellitus
cbai04931  Insulin resistance
cbai04932  Non-alcoholic fatty liver disease
cbai04933  AGE-RAGE signaling pathway in diabetic complications
cbai04935  Growth hormone synthesis, secretion and action
cbai04960  Aldosterone-regulated sodium reabsorption
cbai04973  Carbohydrate digestion and absorption
cbai05010  Alzheimer disease
cbai05017  Spinocerebellar ataxia
cbai05020  Prion disease
cbai05100  Bacterial invasion of epithelial cells
cbai05135  Yersinia infection
cbai05142  Chagas disease
cbai05146  Amoebiasis
cbai05160  Hepatitis C
cbai05161  Hepatitis B
cbai05162  Measles
cbai05163  Human cytomegalovirus infection
cbai05164  Influenza A
cbai05165  Human papillomavirus infection
cbai05166  Human T-cell leukemia virus 1 infection
cbai05167  Kaposi sarcoma-associated herpesvirus infection
cbai05168  Herpes simplex virus 1 infection
cbai05169  Epstein-Barr virus infection
cbai05170  Human immunodeficiency virus 1 infection
cbai05171  Coronavirus disease - COVID-19
cbai05200  Pathways in cancer
cbai05203  Viral carcinogenesis
cbai05205  Proteoglycans in cancer
cbai05206  MicroRNAs in cancer
cbai05207  Chemical carcinogenesis - receptor activation
cbai05208  Chemical carcinogenesis - reactive oxygen species
cbai05210  Colorectal cancer
cbai05211  Renal cell carcinoma
cbai05212  Pancreatic cancer
cbai05213  Endometrial cancer
cbai05214  Glioma
cbai05215  Prostate cancer
cbai05218  Melanoma
cbai05220  Chronic myeloid leukemia
cbai05221  Acute myeloid leukemia
cbai05222  Small cell lung cancer
cbai05223  Non-small cell lung cancer
cbai05224  Breast cancer
cbai05225  Hepatocellular carcinoma
cbai05226  Gastric cancer
cbai05230  Central carbon metabolism in cancer
cbai05231  Choline metabolism in cancer
cbai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cbai05415  Diabetic cardiomyopathy
cbai05417  Lipid and atherosclerosis
cbai05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cbai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    105082679 (PIK3R2)
   04014 Ras signaling pathway
    105082679 (PIK3R2)
   04015 Rap1 signaling pathway
    105082679 (PIK3R2)
   04370 VEGF signaling pathway
    105082679 (PIK3R2)
   04630 JAK-STAT signaling pathway
    105082679 (PIK3R2)
   04668 TNF signaling pathway
    105082679 (PIK3R2)
   04066 HIF-1 signaling pathway
    105082679 (PIK3R2)
   04068 FoxO signaling pathway
    105082679 (PIK3R2)
   04070 Phosphatidylinositol signaling system
    105082679 (PIK3R2)
   04072 Phospholipase D signaling pathway
    105082679 (PIK3R2)
   04071 Sphingolipid signaling pathway
    105082679 (PIK3R2)
   04024 cAMP signaling pathway
    105082679 (PIK3R2)
   04151 PI3K-Akt signaling pathway
    105082679 (PIK3R2)
   04152 AMPK signaling pathway
    105082679 (PIK3R2)
   04150 mTOR signaling pathway
    105082679 (PIK3R2)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    105082679 (PIK3R2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105082679 (PIK3R2)
  09143 Cell growth and death
   04210 Apoptosis
    105082679 (PIK3R2)
   04218 Cellular senescence
    105082679 (PIK3R2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105082679 (PIK3R2)
   04550 Signaling pathways regulating pluripotency of stem cells
    105082679 (PIK3R2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105082679 (PIK3R2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105082679 (PIK3R2)
   04613 Neutrophil extracellular trap formation
    105082679 (PIK3R2)
   04620 Toll-like receptor signaling pathway
    105082679 (PIK3R2)
   04625 C-type lectin receptor signaling pathway
    105082679 (PIK3R2)
   04650 Natural killer cell mediated cytotoxicity
    105082679 (PIK3R2)
   04660 T cell receptor signaling pathway
    105082679 (PIK3R2)
   04662 B cell receptor signaling pathway
    105082679 (PIK3R2)
   04664 Fc epsilon RI signaling pathway
    105082679 (PIK3R2)
   04666 Fc gamma R-mediated phagocytosis
    105082679 (PIK3R2)
   04670 Leukocyte transendothelial migration
    105082679 (PIK3R2)
   04062 Chemokine signaling pathway
    105082679 (PIK3R2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105082679 (PIK3R2)
   04923 Regulation of lipolysis in adipocytes
    105082679 (PIK3R2)
   04929 GnRH secretion
    105082679 (PIK3R2)
   04915 Estrogen signaling pathway
    105082679 (PIK3R2)
   04914 Progesterone-mediated oocyte maturation
    105082679 (PIK3R2)
   04917 Prolactin signaling pathway
    105082679 (PIK3R2)
   04926 Relaxin signaling pathway
    105082679 (PIK3R2)
   04935 Growth hormone synthesis, secretion and action
    105082679 (PIK3R2)
   04919 Thyroid hormone signaling pathway
    105082679 (PIK3R2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105082679 (PIK3R2)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    105082679 (PIK3R2)
  09156 Nervous system
   04725 Cholinergic synapse
    105082679 (PIK3R2)
   04722 Neurotrophin signaling pathway
    105082679 (PIK3R2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105082679 (PIK3R2)
  09158 Development and regeneration
   04360 Axon guidance
    105082679 (PIK3R2)
   04380 Osteoclast differentiation
    105082679 (PIK3R2)
  09149 Aging
   04211 Longevity regulating pathway
    105082679 (PIK3R2)
   04213 Longevity regulating pathway - multiple species
    105082679 (PIK3R2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105082679 (PIK3R2)
   05206 MicroRNAs in cancer
    105082679 (PIK3R2)
   05205 Proteoglycans in cancer
    105082679 (PIK3R2)
   05207 Chemical carcinogenesis - receptor activation
    105082679 (PIK3R2)
   05208 Chemical carcinogenesis - reactive oxygen species
    105082679 (PIK3R2)
   05203 Viral carcinogenesis
    105082679 (PIK3R2)
   05230 Central carbon metabolism in cancer
    105082679 (PIK3R2)
   05231 Choline metabolism in cancer
    105082679 (PIK3R2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105082679 (PIK3R2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105082679 (PIK3R2)
   05212 Pancreatic cancer
    105082679 (PIK3R2)
   05225 Hepatocellular carcinoma
    105082679 (PIK3R2)
   05226 Gastric cancer
    105082679 (PIK3R2)
   05214 Glioma
    105082679 (PIK3R2)
   05221 Acute myeloid leukemia
    105082679 (PIK3R2)
   05220 Chronic myeloid leukemia
    105082679 (PIK3R2)
   05218 Melanoma
    105082679 (PIK3R2)
   05211 Renal cell carcinoma
    105082679 (PIK3R2)
   05215 Prostate cancer
    105082679 (PIK3R2)
   05213 Endometrial cancer
    105082679 (PIK3R2)
   05224 Breast cancer
    105082679 (PIK3R2)
   05222 Small cell lung cancer
    105082679 (PIK3R2)
   05223 Non-small cell lung cancer
    105082679 (PIK3R2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105082679 (PIK3R2)
   05170 Human immunodeficiency virus 1 infection
    105082679 (PIK3R2)
   05161 Hepatitis B
    105082679 (PIK3R2)
   05160 Hepatitis C
    105082679 (PIK3R2)
   05171 Coronavirus disease - COVID-19
    105082679 (PIK3R2)
   05164 Influenza A
    105082679 (PIK3R2)
   05162 Measles
    105082679 (PIK3R2)
   05168 Herpes simplex virus 1 infection
    105082679 (PIK3R2)
   05163 Human cytomegalovirus infection
    105082679 (PIK3R2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105082679 (PIK3R2)
   05169 Epstein-Barr virus infection
    105082679 (PIK3R2)
   05165 Human papillomavirus infection
    105082679 (PIK3R2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    105082679 (PIK3R2)
   05100 Bacterial invasion of epithelial cells
    105082679 (PIK3R2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105082679 (PIK3R2)
   05142 Chagas disease
    105082679 (PIK3R2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105082679 (PIK3R2)
   05017 Spinocerebellar ataxia
    105082679 (PIK3R2)
   05020 Prion disease
    105082679 (PIK3R2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105082679 (PIK3R2)
   05418 Fluid shear stress and atherosclerosis
    105082679 (PIK3R2)
   05415 Diabetic cardiomyopathy
    105082679 (PIK3R2)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105082679 (PIK3R2)
   04932 Non-alcoholic fatty liver disease
    105082679 (PIK3R2)
   04931 Insulin resistance
    105082679 (PIK3R2)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105082679 (PIK3R2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105082679 (PIK3R2)
   01524 Platinum drug resistance
    105082679 (PIK3R2)
   01522 Endocrine resistance
    105082679 (PIK3R2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cbai04131]
    105082679 (PIK3R2)
Membrane trafficking [BR:cbai04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    105082679 (PIK3R2)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH3_1 SH2_1 RhoGAP SH3_9 Ribosomal_L22e
Other DBs
NCBI-GeneID: 105082679
NCBI-ProteinID: XP_010970598
LinkDB
Position
Unknown
AA seq 668 aa
MAGAEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGSERCPQSVGWMPGL
NERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPRDGPPEPGLTLPDLPEQFSP
PDVAPPILVKLVEAIDRTGLDSYRPEPPAARTDWSLSDMEQWDAATLSDGVKGFLLALPS
PLVTPEAAAEAHRALREAAGPVGPVLEPPTLPLHHALTTEPIPDFPALLVEKLLQEHLEE
QEVAPPALPPKPPKAKPASTGLANGGNPPSLQDAEWYWGDISREEVNEKLRDTPDGTFLV
RDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLITHYRHESLAQYN
AKLDTRLLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQEL
QMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRPLSHSSLLYNESRT
KLEQELRVQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNE
TEDQYSLMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVV
VDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPG
PGPPPAAR
NT seq 2007 nt   +upstreamnt  +downstreamnt
atggctggggctgagggcttccaataccgtgctctgtacccattccgccgggaacggcca
gaggacctggagctgctgccaggtgatgtccttgtggtgagccgggcggccctacaggca
ctgggcgtggctgagggcagcgagcgttgcccacagagtgtgggctggatgcctggcctc
aacgagcgtacacggcagcgcggcgacttccctggcacctacgttgagttcctggggcct
gtggccctggcccggcctggccctcgcccacgtggcccccgcccgctgcccgccaggccc
cgagatgggccccctgagccaggcctcacactccctgacctacctgagcagttctcccca
cctgatgtggcgccccctatcctggtgaagcttgtggaggccattgatcggacagggcta
gacagctacagacctgagccacctgccgcacgcacagactggtccctaagtgacatggag
cagtgggacgcggcaaccctgtcagatggcgtgaagggcttcctgctagcgctgccctct
ccccttgtgacacctgaggccgcggccgaagcacatcgagccctgcgggaggccgcaggg
cccgtggggccagtgctggagcccccaaccctgccactgcaccacgcgctcacgactgag
cccatccccgacttccctgctctgctggtggagaagttgcttcaggaacatctggaggag
caggaggttgcgcccccagcactgccgcctaaaccccccaaggcaaagccggcctccaca
ggcctggccaatggggggaacccgccctccctgcaggatgctgaatggtactggggtgac
atctccagggaggaggtaaacgagaaactccgggacacacctgatggtacctttctggtc
cgagatgcatccagcaagatccagggggagtacacgctgacccttaggaaaggcgggaac
aacaagctgatcaaggtcttccaccgagacggtcactacggcttctcagagccgctcacc
ttctgctctgtcgtggacctcatcacccactaccgccatgagtcactggcccagtacaat
gccaagctggacactcggctcctctacccagtgtccaagtaccagcaggaccagattgtc
aaggaggacagcgtggaagcagtgggcgcccagcttaaagtctatcaccagcagtaccaa
gacaagagccgcgagtacgaccagctctatgaggagtacacacgcacctcccaggaactg
cagatgaagcgcacagccatcgaggccttcaatgagaccatcaagatctttgaagagcag
ggccagacgcaagagaagtgcagcaaggagtatctggagcgcttccggcgtgagggcaat
gagaaggagatgcagaggcctctgagccactcctccctcctctacaacgagagccgcaca
aagctggagcaggagctacgggtgcaggcctctgacaaccgagagatcgacaagcgcatg
aacagcctcaagccagacctcatgcagctgcgcaagatccgagaccagtaccttgtgtgg
ctcactcagaaaggtgcccggcagaagaaaatcaacgaatggttgggaatcaaaaacgag
actgaggaccagtactcactgatggaagatgaggatgaccttccccaccatgaggaacgc
acgtggtatgtaggcaagatcaaccgcacacaagctgaggaaatgctgagtggcaagcgg
gatggcaccttcctcatccgtgagagcagccagcgcggctgctacgcctgctccgtggtg
gtggatggtgacaccaaacactgcgttatctaccgcacagccacgggcttcggctttgca
gagccctataacttgtacgggtcactgaaggagctggtgctgcactaccagcatgcctca
ctggtgcagcacaacgacgcgctcaccgtcacgctcgcccatcccgtgcgcgccccaggc
cccgggcccccacctgccgcccgctga

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