Camelus bactrianus (Bactrian camel): 105082946 Help Entry 105082946         CDS       T07534                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism cbai  Camelus bactrianus (Bactrian camel) Pathway cbai00230   Purine metabolism cbai01100   Metabolic pathways cbai01522   Endocrine resistance cbai04015   Rap1 signaling pathway cbai04020   Calcium signaling pathway cbai04022   cGMP-PKG signaling pathway cbai04024   cAMP signaling pathway cbai04062   Chemokine signaling pathway cbai04072   Phospholipase D signaling pathway cbai04081   Hormone signaling cbai04082   Neuroactive ligand signaling cbai04114   Oocyte meiosis cbai04211   Longevity regulating pathway cbai04213   Longevity regulating pathway - multiple species cbai04261   Adrenergic signaling in cardiomyocytes cbai04270   Vascular smooth muscle contraction cbai04371   Apelin signaling pathway cbai04540   Gap junction cbai04611   Platelet activation cbai04713   Circadian entrainment cbai04714   Thermogenesis cbai04720   Long-term potentiation cbai04723   Retrograde endocannabinoid signaling cbai04724   Glutamatergic synapse cbai04725   Cholinergic synapse cbai04727   GABAergic synapse cbai04742   Taste transduction cbai04750   Inflammatory mediator regulation of TRP channels cbai04911   Insulin secretion cbai04912   GnRH signaling pathway cbai04913   Ovarian steroidogenesis cbai04914   Progesterone-mediated oocyte maturation cbai04915   Estrogen signaling pathway cbai04916   Melanogenesis cbai04918   Thyroid hormone synthesis cbai04921   Oxytocin signaling pathway cbai04923   Regulation of lipolysis in adipocytes cbai04925   Aldosterone synthesis and secretion cbai04926   Relaxin signaling pathway cbai04927   Cortisol synthesis and secretion cbai04928   Parathyroid hormone synthesis, secretion and action cbai04934   Cushing syndrome cbai04935   Growth hormone synthesis, secretion and action cbai04970   Salivary secretion cbai04971   Gastric acid secretion cbai04972   Pancreatic secretion cbai04976   Bile secretion cbai05032   Morphine addiction cbai05163   Human cytomegalovirus infection cbai05166   Human T-cell leukemia virus 1 infection cbai05200   Pathways in cancer cbai05207   Chemical carcinogenesis - receptor activation cbai05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:cbai00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105082946 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105082946 (ADCY8)    04371 Apelin signaling pathway     105082946 (ADCY8)    04020 Calcium signaling pathway     105082946 (ADCY8)    04072 Phospholipase D signaling pathway     105082946 (ADCY8)    04024 cAMP signaling pathway     105082946 (ADCY8)    04022 cGMP-PKG signaling pathway     105082946 (ADCY8)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105082946 (ADCY8)    04081 Hormone signaling     105082946 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105082946 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     105082946 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105082946 (ADCY8)    04062 Chemokine signaling pathway     105082946 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     105082946 (ADCY8)    04923 Regulation of lipolysis in adipocytes     105082946 (ADCY8)    04912 GnRH signaling pathway     105082946 (ADCY8)    04913 Ovarian steroidogenesis     105082946 (ADCY8)    04915 Estrogen signaling pathway     105082946 (ADCY8)    04914 Progesterone-mediated oocyte maturation     105082946 (ADCY8)    04921 Oxytocin signaling pathway     105082946 (ADCY8)    04926 Relaxin signaling pathway     105082946 (ADCY8)    04935 Growth hormone synthesis, secretion and action     105082946 (ADCY8)    04918 Thyroid hormone synthesis     105082946 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     105082946 (ADCY8)    04916 Melanogenesis     105082946 (ADCY8)    04925 Aldosterone synthesis and secretion     105082946 (ADCY8)    04927 Cortisol synthesis and secretion     105082946 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105082946 (ADCY8)    04270 Vascular smooth muscle contraction     105082946 (ADCY8)   09154 Digestive system    04970 Salivary secretion     105082946 (ADCY8)    04971 Gastric acid secretion     105082946 (ADCY8)    04972 Pancreatic secretion     105082946 (ADCY8)    04976 Bile secretion     105082946 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     105082946 (ADCY8)    04727 GABAergic synapse     105082946 (ADCY8)    04725 Cholinergic synapse     105082946 (ADCY8)    04720 Long-term potentiation     105082946 (ADCY8)    04723 Retrograde endocannabinoid signaling     105082946 (ADCY8)   09157 Sensory system    04742 Taste transduction     105082946 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     105082946 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     105082946 (ADCY8)    04213 Longevity regulating pathway - multiple species     105082946 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     105082946 (ADCY8)    04714 Thermogenesis     105082946 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105082946 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     105082946 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105082946 (ADCY8)    05163 Human cytomegalovirus infection     105082946 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     105082946 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105082946 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105082946 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105082946 (ADCY8) Enzymes [BR:cbai01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105082946 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N TBK1_ULD Adcy_cons_dom Motif Other DBs NCBI-GeneID:  105082946 NCBI-ProteinID:  XP_010970960 UniProt:  A0A9W3FDN0 LinkDB All DBs Position Unknown AA seq 1001 aa AA seqDB search MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY SGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQV VLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLE TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG IPGRIHISKATLDCLNGDYNVEEGYGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKE SVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNYSQMRDEVFKSNLVCAFIVLLFITAIQ SLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLARNVIIF ASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVF LRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLLMAMFLL AVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDN EELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDI EKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIG ISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYR GEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQ LLNENNNTGIIKAHYNRRTLLTPSGPEPGAQAEGADKSELP NT seq 3006 nt NT seq  +upstreamnt  +downstreamnt atgaacgtgctggacgtgctgaccaaactcaccctcttggttctccacttgagcctggcc tcggcccccatggacccgctcaagggcatcctgctgggcttcttcactggcatagaggtg gtgatctgcgccctggtggtggtcaggaaggacaccacctcgcacacgtacctgcagtac agcggcgtggtcacctgggtggccatgaccacccagatcttagccgcaggtctcggctac gggctgctgggggacggcatcggctacgtgctcttcacgctcttcgccacctacagcatg ctgccgctgccgctcacctgggccatcctggccggcctgggcacctccttgctgcaggta gtcctccaagtggtcatccccaggctggcggtcatttccatcaaccaggttgtggctcag gcagtgttattcatgtgtatgaacacagctggcatcttcatcagttacctatcagatcgg gcccagcgccaagccttcctggagacgcggaggtgcgtggaggccaggctgcggctggag acggaaaaccaaagacaggagcggcttgtgctgtccgtgctgccccggtttgttgtcctg gaaatgatcaacgacatgaccaacgtggaagacgagcacctgcagcaccaattccatcgg atctacatccaccgctatgagaacgtcagtattctttttgcagatgttaaaggatttacc aacctctccacgaccttgtctgctcaggagctggtcaggatgctcaacgagctctttgcc agatttgatcgactggcccatgagcatcactgccttcgcattaaaatcctgggggactgc tactactgcgtttcgggacttcccgagccccgccaggaccacgcccactgctgcgttgaa atgggcctcagcatgatcaaaactatcaggtacgtgcggtcaaggacgaagcacgacgtt gacatgcggatcggaatccactcgggctccgtactgtgtggcgtgttgggcctgcggaag tggcagtttgatgtctggtcttgggatgtggacattgcgaacaaacttgaatctggagga atccccgggaggattcacatttctaaagccaccctggactgcctcaacggggactataat gtggaagagggctacggaaaagagaggaatgaattcctgaggaagcataacatagagacc tatttaattaagcagcctgaggacagtctactgtctttgcccgaagacattgtcaaggag tctgtgagctcctcagacaggagaaacagtggggcaacgttcacagaaggatcctggagc cctgaactgcccttcgataacatagtggggaaacagaactattctcaaatgagggatgaa gtattcaagtcaaacttggtctgtgcatttatcgtccttctgtttatcacggcaatacaa agtttgcttccttcttcaagggtgatgccaatggccatccagttttccatcctgattatg ctgcactcggctctggtcctcatcaccacagcagaggattataagtgtttgcccttggtc ctccggaaaacttgctgttggattaacgagacctatttggccagaaacgtcatcatcttt gcatccatcttgattaatttcctgggcgccatcttaaatatcctgtggtgtgattttgac aagtcgatacccttgaagaacctgactttcaattcctcagctgtgtttacagatatctgc tcctacccagagtacttcgtcttcacgggggtgctggccatggtgacatgtgcggttttc ctccgacttaattccgtcctgaagctggctgtgctgctgattatgatcgctatctatgcc ctgctgactgagaccatctatgcaggactctttctgcgctacgacaacctgaaccacagt ggagaagatttcctggggaccaaggaggcatcgctgctgctgatggccatgttcctcctc gctgtgttctaccatggacagcagctggagtacaccgcccgcctggacttcctttggcga gtgcaggccaaagaggagatcaacgagatgaaggagctgagggagcacaacgagaacatg ctgcggaacatcctgcccagccacgtggcccgccacttcctggagaaggaccgggacaac gaggagctgtattcccagtcctatgatgccgttggggtgatgtttgcctccatcccaggg tttgcagacttttactctcagactgaaatgaataaccaaggagtggaatgcctacgcctg ctgaatgagatcattgccgacttcgatgagctgctcggtgaagaccgatttcaagacatt gagaagattaagaccattggcagcacctacatggctgtgtctggcctgtcacctgagaaa cagcaatgtgaagacaagtgggggcacctgtgcgccctggccgacttctctcttgccctg accgaaagcatacaggagatcaacaagcactctttcaacaatttcgagctccggattggc atcagccacggctcagtggtcgctggcgttatcggcgctaagaagccacagtacgacatt tggggcaagaccgtgaacctggcaagtcggatggacagcacgggggtcagcggccggatc caggtcccagaggagacctatctcatcctgaaggaccagggctttgcctttgactaccgt ggggagatctacgtgaagggcatcagtgagcaggaaggaaaaatcaaaacgtactttctc ctgggaagagtccaacccaacccattcatcctgcccccgagaagactgcccgggcagtac tccttggccgcggtggtcctgggcctcgtgcagtccctcaacaggcagaggcagaagcag ctcctgaacgagaacaacaacacaggcatcatcaaggcccattacaaccggcggactttg ttgacgcccagcgggccagagccgggagcccaagccgaaggcgccgacaagtccgagttg ccataa

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