KEGG   PATHWAY: cby00740
Entry
cby00740                    Pathway                                
Name
Riboflavin metabolism - Clostridium botulinum A2
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
cby00740  Riboflavin metabolism
cby00740

Other DBs
GO: 0006771
Organism
Clostridium botulinum A2 [GN:cby]
Gene
CLM_0532  thiM; hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
CLM_0557  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CLM_2030  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CLM_2460  thiM; hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
CLM_2707  ribF; riboflavin biosynthesis protein RibF [KO:K11753] [EC:2.7.1.26 2.7.7.2]
CLM_3259  ribH; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
CLM_3260  ribAB; bifunctional riboflavin biosynthesis protein RibAB [KO:K14652] [EC:4.1.99.12 3.5.4.25]
CLM_3261  ribE; riboflavin synthase, alpha subunit [KO:K00793] [EC:2.5.1.9]
CLM_3262  ribD; riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
cby00030  Pentose phosphate pathway
cby00040  Pentose and glucuronate interconversions
cby00230  Purine metabolism
cby00860  Porphyrin metabolism
cby00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   

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