Cervus canadensis (wapiti): 122426570 Help Entry 122426570         CDS       T07554                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism ccad  Cervus canadensis (wapiti) Pathway ccad01524   Platinum drug resistance ccad04115   p53 signaling pathway ccad04210   Apoptosis ccad04215   Apoptosis - multiple species ccad04217   Necroptosis ccad04620   Toll-like receptor signaling pathway ccad04621   NOD-like receptor signaling pathway ccad04622   RIG-I-like receptor signaling pathway ccad04623   Cytosolic DNA-sensing pathway ccad04625   C-type lectin receptor signaling pathway ccad04657   IL-17 signaling pathway ccad04668   TNF signaling pathway ccad04932   Non-alcoholic fatty liver disease ccad04936   Alcoholic liver disease ccad05010   Alzheimer disease ccad05016   Huntington disease ccad05022   Pathways of neurodegeneration - multiple diseases ccad05132   Salmonella infection ccad05134   Legionellosis ccad05142   Chagas disease ccad05145   Toxoplasmosis ccad05152   Tuberculosis ccad05160   Hepatitis C ccad05161   Hepatitis B ccad05162   Measles ccad05163   Human cytomegalovirus infection ccad05164   Influenza A ccad05165   Human papillomavirus infection ccad05167   Kaposi sarcoma-associated herpesvirus infection ccad05168   Herpes simplex virus 1 infection ccad05169   Epstein-Barr virus infection ccad05170   Human immunodeficiency virus 1 infection ccad05200   Pathways in cancer ccad05203   Viral carcinogenesis ccad05416   Viral myocarditis ccad05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ccad00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     122426570 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     122426570 (CASP8)    04215 Apoptosis - multiple species     122426570 (CASP8)    04217 Necroptosis     122426570 (CASP8)    04115 p53 signaling pathway     122426570 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     122426570 (CASP8)    04621 NOD-like receptor signaling pathway     122426570 (CASP8)    04622 RIG-I-like receptor signaling pathway     122426570 (CASP8)    04623 Cytosolic DNA-sensing pathway     122426570 (CASP8)    04625 C-type lectin receptor signaling pathway     122426570 (CASP8)    04657 IL-17 signaling pathway     122426570 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122426570 (CASP8)    05203 Viral carcinogenesis     122426570 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     122426570 (CASP8)    05161 Hepatitis B     122426570 (CASP8)    05160 Hepatitis C     122426570 (CASP8)    05164 Influenza A     122426570 (CASP8)    05162 Measles     122426570 (CASP8)    05168 Herpes simplex virus 1 infection     122426570 (CASP8)    05163 Human cytomegalovirus infection     122426570 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     122426570 (CASP8)    05169 Epstein-Barr virus infection     122426570 (CASP8)    05165 Human papillomavirus infection     122426570 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     122426570 (CASP8)    05134 Legionellosis     122426570 (CASP8)    05152 Tuberculosis     122426570 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     122426570 (CASP8)    05142 Chagas disease     122426570 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     122426570 (CASP8)    05016 Huntington disease     122426570 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     122426570 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     122426570 (CASP8)    05416 Viral myocarditis     122426570 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     122426570 (CASP8)    04932 Non-alcoholic fatty liver disease     122426570 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     122426570 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ccad01002]     122426570 (CASP8) Enzymes [BR:ccad01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      122426570 (CASP8) Peptidases and inhibitors [BR:ccad01002]  Cysteine peptidases   Family C14: caspase family    122426570 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  122426570 NCBI-ProteinID:  XP_043301517 LinkDB All DBs Position 24:complement(44107506..44129958) Genome browser AA seq 486 aa AA seqDB search MDLTRCLYKIGEELGSDDLAALKFLSRDHIPYRKQEPINDAWMLFQRLQERRILEESNLS FLKELLFRVNRLDLLRYYLDTSEEEMKRELHIPGRAQISAYRILLFQISEDVNKVELKEF KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGEENLDTLKRICEQVNKSLLKKIIDYEE LRKERRMSLERDPDEFSNDTSQPLPEEGSSEMLAVSDSPGEQDSEVQTSDTVYRMTSKPR GYCLIINNYDFSIARRKVPELQKLKDRSGTHFDAEALDKTFRELHFEIVHYRDQTAEEIH KALEFYQKKDHRNRDCFICCILSHGNRGIIYGTDGQEAPIYELTSYFTGLKCPSLVGKPK IFFIQACQGDDYQRGIAVETDSEQMEVCLEMDSAPRRRYIPDEADFLLGMATVNNCVSYR SIREGTWYIQSLCQNLRKRCPRGEDILTILTKVNFEVSNKDDKRNMGKQMPQPTFTLRKK LFFPLN NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt atggatctcactcgatgtctctataaaattggggaagagctgggcagtgacgacctggct gccctcaagttcctaagccgggaccacatcccatataggaagcaggaacccatcaacgat gcctggatgctattccagaggctccaagaaaggagaatcttggaggaaagcaatctgtcc ttcttgaaggagctgcttttccgagtgaatagactggatctgctgcgttactacttggac accagcgaggaggagatgaagagggagcttcacatacccggcagggcccagatctctgcc tacaggatcctgcttttccagatttcagaagatgtgaacaaagtggaattgaaggagttt aagttttttttgagccaggagattgccaaatgtaagctggatgatgacatgactttgctt gatattttcgtggagatggagaagaggaccatcctaggggaagaaaacttggacaccctg aaaagaatctgtgagcaggtcaacaagagcctgctgaagaaaatcattgattatgaagaa ttaagaaaagagagaagaatgagccttgaaagagatccagatgaattttcaaatgataca tcacaaccgcttccagaggagggctcctctgagatgctggccgtgtcagactctccagga gaacaggacagtgaggtgcagacatccgacacagtttaccgaatgacaagcaaacctcgg ggatactgtttgatcattaacaattacgattttagcatagcacggaggaaggtgcccgaa cttcagaaactaaaggataggagtggaacacacttcgatgcagaggctttggacaagacc tttagggaacttcattttgagatagtgcactacagagaccaaacagcagaggaaatccat aaggctctggaattctaccagaagaaggaccacagaaacagagactgcttcatctgctgc atcctctcccatggaaaccggggcatcatctatggcaccgatgggcaagaagcccccatc tatgagctgacctcttacttcactggcttaaaatgcccttcccttgttggcaaacccaaa atcttttttattcaggcttgtcaaggggatgactaccagagaggtatagctgttgagacc gactcagaacagatggaagtctgtttagaaatggattcagcacctcggaggagatatatc ccagatgaggctgactttctgctggggatggccactgtcaacaactgtgtctcctaccga agcatcagggaggggacctggtatatccaatcgctttgccagaacctgagaaaaagatgt cctaggggtgaagacattctcaccatcctaaccaaggtgaacttcgaagtaagcaataag gatgacaagagaaatatgggcaaacagatgccacaacctactttcacactgcgaaaaaaa ctcttctttcctcttaattga

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