Cervus canadensis (wapiti): 122426634 Help Entry 122426634         CDS       T07554                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism ccad  Cervus canadensis (wapiti) Pathway ccad04064   NF-kappa B signaling pathway ccad04380   Osteoclast differentiation ccad04517   IgSF CAM signaling ccad04650   Natural killer cell mediated cytotoxicity ccad04658   Th1 and Th2 cell differentiation ccad04659   Th17 cell differentiation ccad04660   T cell receptor signaling pathway ccad05135   Yersinia infection ccad05166   Human T-cell leukemia virus 1 infection ccad05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ccad05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:ccad00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     122426634 (LCK)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     122426634 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     122426634 (LCK)    04660 T cell receptor signaling pathway     122426634 (LCK)    04658 Th1 and Th2 cell differentiation     122426634 (LCK)    04659 Th17 cell differentiation     122426634 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     122426634 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     122426634 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122426634 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     122426634 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     122426634 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ccad01001]     122426634 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:ccad03036]     122426634 (LCK) Enzymes [BR:ccad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      122426634 (LCK) Protein kinases [BR:ccad01001]  Non-receptor tyrosine kinases   SRC family    122426634 (LCK) Chromosome and associated proteins [BR:ccad03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     122426634 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase Kdo SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  122426634 NCBI-ProteinID:  XP_043301638 LinkDB All DBs Position 24:14147725..14168661 Genome browser AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLDSKTTLPMRNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKH YKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaacccagaagatgactggatggaaaacatcgatgtatgt gaaaactgccactaccccatagtcccactggatagcaagaccacgctgcccatgcggaat ggctctgaagtgcgtgatccactggtcacctacgagggatccaaccccccagcttctcca ctgcaagacaacctggttatcgccctgcacagctatgagccttctcacgacggagacctg ggcttcgagaagggtgaacagctccgtatcctggagcagagcggcgagtggtggaaggcg cagtccctgaccacgggccaggaaggtttcatccccttcaacttcgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaccctgagccgcaaagacgcggagaggcag ctcctggcgccggggaacacgcacgggtccttcctgatccgggagagcgagagcacggct ggatcgttttcactgtcggtccgggacttcgaccagacccagggagaagtggtgaaacat tacaagatccgtaacctggacaaaggcggcttctacatctcgccccgcgtcacttttccc ggcttgcacgagctggtccgccattacatgaatacttcggacgggctgtgcacacggctg agccgcccctgccagacccagaagccccagaagccgtggtgggaggatgagtgggaggtt cccagggagacgctgaagctggtggagcggctgggggctggccagttcggagaggtgtgg atggggtactacaacgggcacacgaaggtggcagtcaagagcctgaagcagggcagcatg tcccccgatgccttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctg gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatatatggag aacggaagcctggtggattttctcaagacctccgaaggcatcaagctgactatcaacaaa ctcttggacatggccgcccaaatcgcagagggcatggcattcattgaagaacggaattat atccaccgcgacttgagggctgccaacatcctggtgtcccatagcctgagctgcaagatc gcagactttggtctagcacgcctcattgaggacaacgagtacacagccagggagggtgcc aagtttcccattaagtggacagccccagaagccattaactatgggacattcaccatcaag tcggacgtgtggtctttcgggatcctgctaacagagattgtcactcatggtcgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggta cgacctgacaactgcccggaggagttgtaccagcttatgatgctgtgctggaaggagcgc ccagaggaccggcccacttttgactacctgcgcagcgtgttggaggacttcttcacggcc acggagggccaataccaaccccaaccctga

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