KEGG   Cervus canadensis (wapiti): 122436698
Entry
122436698         CDS       T07554                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
ccad  Cervus canadensis (wapiti)
Pathway
ccad01521  EGFR tyrosine kinase inhibitor resistance
ccad01522  Endocrine resistance
ccad04010  MAPK signaling pathway
ccad04012  ErbB signaling pathway
ccad04014  Ras signaling pathway
ccad04062  Chemokine signaling pathway
ccad04068  FoxO signaling pathway
ccad04072  Phospholipase D signaling pathway
ccad04150  mTOR signaling pathway
ccad04151  PI3K-Akt signaling pathway
ccad04380  Osteoclast differentiation
ccad04510  Focal adhesion
ccad04540  Gap junction
ccad04550  Signaling pathways regulating pluripotency of stem cells
ccad04630  JAK-STAT signaling pathway
ccad04650  Natural killer cell mediated cytotoxicity
ccad04660  T cell receptor signaling pathway
ccad04662  B cell receptor signaling pathway
ccad04664  Fc epsilon RI signaling pathway
ccad04714  Thermogenesis
ccad04722  Neurotrophin signaling pathway
ccad04910  Insulin signaling pathway
ccad04912  GnRH signaling pathway
ccad04915  Estrogen signaling pathway
ccad04917  Prolactin signaling pathway
ccad04926  Relaxin signaling pathway
ccad04935  Growth hormone synthesis, secretion and action
ccad05034  Alcoholism
ccad05160  Hepatitis C
ccad05161  Hepatitis B
ccad05163  Human cytomegalovirus infection
ccad05165  Human papillomavirus infection
ccad05200  Pathways in cancer
ccad05203  Viral carcinogenesis
ccad05205  Proteoglycans in cancer
ccad05206  MicroRNAs in cancer
ccad05207  Chemical carcinogenesis - receptor activation
ccad05208  Chemical carcinogenesis - reactive oxygen species
ccad05210  Colorectal cancer
ccad05211  Renal cell carcinoma
ccad05213  Endometrial cancer
ccad05214  Glioma
ccad05215  Prostate cancer
ccad05220  Chronic myeloid leukemia
ccad05221  Acute myeloid leukemia
ccad05223  Non-small cell lung cancer
ccad05224  Breast cancer
ccad05225  Hepatocellular carcinoma
ccad05226  Gastric cancer
ccad05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ccad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    122436698 (GRB2)
   04630 JAK-STAT signaling pathway
    122436698 (GRB2)
   04068 FoxO signaling pathway
    122436698 (GRB2)
   04072 Phospholipase D signaling pathway
    122436698 (GRB2)
   04151 PI3K-Akt signaling pathway
    122436698 (GRB2)
   04150 mTOR signaling pathway
    122436698 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    122436698 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    122436698 (GRB2)
   04660 T cell receptor signaling pathway
    122436698 (GRB2)
   04662 B cell receptor signaling pathway
    122436698 (GRB2)
   04664 Fc epsilon RI signaling pathway
    122436698 (GRB2)
   04062 Chemokine signaling pathway
    122436698 (GRB2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    122436698 (GRB2)
   04917 Prolactin signaling pathway
    122436698 (GRB2)
   04926 Relaxin signaling pathway
    122436698 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    122436698 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    122436698 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122436698 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    122436698 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122436698 (GRB2)
   05206 MicroRNAs in cancer
    122436698 (GRB2)
   05205 Proteoglycans in cancer
    122436698 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    122436698 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    122436698 (GRB2)
   05203 Viral carcinogenesis
    122436698 (GRB2)
   05231 Choline metabolism in cancer
    122436698 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122436698 (GRB2)
   05225 Hepatocellular carcinoma
    122436698 (GRB2)
   05226 Gastric cancer
    122436698 (GRB2)
   05214 Glioma
    122436698 (GRB2)
   05221 Acute myeloid leukemia
    122436698 (GRB2)
   05220 Chronic myeloid leukemia
    122436698 (GRB2)
   05211 Renal cell carcinoma
    122436698 (GRB2)
   05215 Prostate cancer
    122436698 (GRB2)
   05213 Endometrial cancer
    122436698 (GRB2)
   05224 Breast cancer
    122436698 (GRB2)
   05223 Non-small cell lung cancer
    122436698 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    122436698 (GRB2)
   05160 Hepatitis C
    122436698 (GRB2)
   05163 Human cytomegalovirus infection
    122436698 (GRB2)
   05165 Human papillomavirus infection
    122436698 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    122436698 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122436698 (GRB2)
   01522 Endocrine resistance
    122436698 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccad04131]
    122436698 (GRB2)
Membrane trafficking [BR:ccad04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    122436698 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 DUF7145 SH2_2 DUF5093 hSH3 SH3_4 DUF7063
Other DBs
NCBI-GeneID: 122436698
NCBI-ProteinID: XP_043316609
LinkDB
Position
1:complement(6858167..6922352)
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatgggaaagacggcttcattcccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgctcagcaaacagcggcatgat
ggggcctttcttatccgagagagcgagagtgctcctggggatttctccctctccgtcaag
tttggaaatgatgtacagcacttcaaggtgctccgagatggggctggcaagtatttcctc
tgggtggtcaagttcaactctttgaatgagctggtagattatcacagatctacatccgtc
tccagaaaccagcagatatttctccgggacatagagcaggtgccgcagcagccgacatat
gtccaagccctctttgactttgacccccaagaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgttcccacgtaattacgtcacccccgtgaaccggaacgtctaa

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