Cervus canadensis (wapiti): 122438514 Help Entry 122438514         CDS       T07554                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ccad  Cervus canadensis (wapiti) Pathway ccad00230   Purine metabolism ccad01100   Metabolic pathways ccad01522   Endocrine resistance ccad04015   Rap1 signaling pathway ccad04020   Calcium signaling pathway ccad04022   cGMP-PKG signaling pathway ccad04024   cAMP signaling pathway ccad04062   Chemokine signaling pathway ccad04072   Phospholipase D signaling pathway ccad04081   Hormone signaling ccad04082   Neuroactive ligand signaling ccad04114   Oocyte meiosis ccad04211   Longevity regulating pathway ccad04213   Longevity regulating pathway - multiple species ccad04261   Adrenergic signaling in cardiomyocytes ccad04270   Vascular smooth muscle contraction ccad04371   Apelin signaling pathway ccad04540   Gap junction ccad04611   Platelet activation ccad04713   Circadian entrainment ccad04714   Thermogenesis ccad04720   Long-term potentiation ccad04723   Retrograde endocannabinoid signaling ccad04724   Glutamatergic synapse ccad04725   Cholinergic synapse ccad04727   GABAergic synapse ccad04750   Inflammatory mediator regulation of TRP channels ccad04911   Insulin secretion ccad04912   GnRH signaling pathway ccad04913   Ovarian steroidogenesis ccad04914   Progesterone-mediated oocyte maturation ccad04915   Estrogen signaling pathway ccad04916   Melanogenesis ccad04918   Thyroid hormone synthesis ccad04921   Oxytocin signaling pathway ccad04923   Regulation of lipolysis in adipocytes ccad04925   Aldosterone synthesis and secretion ccad04926   Relaxin signaling pathway ccad04927   Cortisol synthesis and secretion ccad04928   Parathyroid hormone synthesis, secretion and action ccad04934   Cushing syndrome ccad04935   Growth hormone synthesis, secretion and action ccad04970   Salivary secretion ccad04971   Gastric acid secretion ccad04972   Pancreatic secretion ccad04976   Bile secretion ccad05032   Morphine addiction ccad05142   Chagas disease ccad05146   Amoebiasis ccad05163   Human cytomegalovirus infection ccad05166   Human T-cell leukemia virus 1 infection ccad05200   Pathways in cancer ccad05207   Chemical carcinogenesis - receptor activation ccad05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ccad00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     122438514 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122438514 (ADCY1)    04371 Apelin signaling pathway     122438514 (ADCY1)    04020 Calcium signaling pathway     122438514 (ADCY1)    04072 Phospholipase D signaling pathway     122438514 (ADCY1)    04024 cAMP signaling pathway     122438514 (ADCY1)    04022 cGMP-PKG signaling pathway     122438514 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     122438514 (ADCY1)    04081 Hormone signaling     122438514 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     122438514 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     122438514 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122438514 (ADCY1)    04062 Chemokine signaling pathway     122438514 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     122438514 (ADCY1)    04923 Regulation of lipolysis in adipocytes     122438514 (ADCY1)    04912 GnRH signaling pathway     122438514 (ADCY1)    04913 Ovarian steroidogenesis     122438514 (ADCY1)    04915 Estrogen signaling pathway     122438514 (ADCY1)    04914 Progesterone-mediated oocyte maturation     122438514 (ADCY1)    04921 Oxytocin signaling pathway     122438514 (ADCY1)    04926 Relaxin signaling pathway     122438514 (ADCY1)    04935 Growth hormone synthesis, secretion and action     122438514 (ADCY1)    04918 Thyroid hormone synthesis     122438514 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     122438514 (ADCY1)    04916 Melanogenesis     122438514 (ADCY1)    04925 Aldosterone synthesis and secretion     122438514 (ADCY1)    04927 Cortisol synthesis and secretion     122438514 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     122438514 (ADCY1)    04270 Vascular smooth muscle contraction     122438514 (ADCY1)   09154 Digestive system    04970 Salivary secretion     122438514 (ADCY1)    04971 Gastric acid secretion     122438514 (ADCY1)    04972 Pancreatic secretion     122438514 (ADCY1)    04976 Bile secretion     122438514 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     122438514 (ADCY1)    04727 GABAergic synapse     122438514 (ADCY1)    04725 Cholinergic synapse     122438514 (ADCY1)    04720 Long-term potentiation     122438514 (ADCY1)    04723 Retrograde endocannabinoid signaling     122438514 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     122438514 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     122438514 (ADCY1)    04213 Longevity regulating pathway - multiple species     122438514 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     122438514 (ADCY1)    04714 Thermogenesis     122438514 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122438514 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     122438514 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122438514 (ADCY1)    05163 Human cytomegalovirus infection     122438514 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     122438514 (ADCY1)    05142 Chagas disease     122438514 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     122438514 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     122438514 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122438514 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     122438514 (ADCY1) Enzymes [BR:ccad01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      122438514 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF7246 Motif Other DBs NCBI-GeneID:  122438514 NCBI-ProteinID:  XP_043319370 LinkDB All DBs Position 3:complement(71942411..72047420) Genome browser AA seq 1134 aa AA seqDB search MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQ AATLKALAMLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLP VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNMYGVFVRILAERA QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA LRTASEKLRNRSSFSTNVVQATPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERE RKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNGSLVVLSSGGGDPV LPAPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGA GAVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDNKRIL FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIE MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR IQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMCPY GRAGLQTRLAAGHPLVPPAAGLPVGPGPGTLQGSGLAPGPPGQHLPPGASGKEA NT seq 3405 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggcggcggaggcggaggcggcgcgggcgagtct gggggcgccgagcgggcggcggggccgggcggccggcgcgggctgcgggcgtgcgatgag gagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcag gcggcgacgctgaaggcgctggccatgctcagcctgctggcgggcgcgctggccctggcc gagctgctgggcgcgccggggcccgcgcccggcctggccaagggctcgcaccccgtgcac tgcgtgctcttcctggcgctgctcgtggtcaccaacgtccgctcgctgcaggtgccccag ctgcagcaggtcggccagctcgcgctgctcttcagcctcaccttcgcgctgctatgctgt cccttcgcgctcggcggccccgccggtgcccacgccggggcggcagcggtgccggcgaca gccgatcagggagtctggcagctccttttggtcaccttcgtgtcctatgccctgctgccc gtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttgctggtc acggctaccttggtccccgccaagcgcccacgtctctggagaacgctgggtgccaatgct ctgctcttccttggtgtgaacatgtatggggtcttcgtgaggatcctggctgagcgcgcc cagaggaaggccttcctgcaggcccggaactgcattgaggaccggctgaggctggaggac gagaatgagaagcaggagcggctgctcatgagcctcctgcctcggaatgttgccatggag atgaaggaggacttcctgaagccccctgagaggattttccacaagatttacatccagcgg cacgacaacgtgagcatcctctttgcagacatcgtgggcttcacgggcttggcgtcacag tgtacggcccaggagctggtgaaactcctcaacgagctcttcgggaagtttgatgagctg gccacggagaaccactgccgccgcatcaagatcctgggagactgctactactgcgtgtcc ggcctcacgcagcccaagaccgaccacgcccactgctgcgtggagatgggcctggacatg atcgacaccatcacgtctgtggccgaggccactgaggtggacctgaacatgcgtgtgggc ttgcacaccggcagggtcctctgcggggtcctgggcctgcgtaagtggcagtatgacgtg tggtccaacgacgtgaccctggccaacgtcatggaggctgccggcctgcctgggaaggtt cacatcacaaagaccaccctggcgtgcctgaacggtgactatgaggtggagccggggcac ggacacgagaggaacagttttctgaaaactcataacatcgagacctttttcattgtgccc tcgcatcggcgaaagatatttccagggctgattctctcagacataaaaccggccaagagg atgaagttcaagaccgtgtgctacctgctggtgcagctcatgcactgccggaagatgttc aaggcggagatccctttctctaatgtcatgacctgcgaggacgacgacaagcggagggca ttgagaacagcctcggaaaaactcagaaaccgctcgtctttctctacaaacgttgtccaa gccacccccgggacacgtgtcaacaggtacatcggccgcctcttggaagcccgccagatg gagctggagatggcagacctgaacttcttcaccctgaagtacaagcaggctgagagagag cgaaagtaccaccagcttcaggacgagtatttcaccagcgccgtggtcctggctctcatt ctggccgccttattcggccttgtctaccttctaataatcccgcagagtgtggccgtcctg ctcctgctggtgttctgcatctgcttcctggtggcctgtgtcctgtacctacacatcacc cgggtccagtgttttccagggtgcctgaccatccagatccgcaccgtcttatgcatcttc atcgtggtcttaatctactctgtggcccaaggctgtgtggtgggctgcctgccttgggcc tggagctccagtcccaacgggtccctggtggtcctgtcttccgggggcggggacccagtg ctgcctgccccgccctgcgagtctgcgccccatgccctgctgtgcggcctcgtgggcacc ctccctctggccatattcctgcgggtctcctccttgccaaaaatgatcctgctcgccgtg ctcaccacctcctacatcctcgtcctggagctcagcgggtacacgaaggccatgggggcc ggtgccgtctcagggcgcagcttcgagccgatcgtggccatcctgctattctcgtgcacg ctggccctgcacgcccggcaggtggatgtcaagctgcggctggactacctctgggcggcc caggcagaggaggagcgggacgacatggagagagtgaagctggacaacaagaggattctc ttcaacctcctgccagcccacgttgcccagcacttcctgatgtccaaccctcgcaacatg gacctgtactaccagtcgtactcgcaagtgggggtcatgtttgcatccatccccaacttc aatgacttctacatcgagttggatggcaacaacatgggcgtggagtgtctgcgccttctg aacgagatcatcgccgactttgacgagctcatggacaaagacttttacaaggacctagag aagatcaagaccatcgggagcacatacatggccgctgtgggactggcgcctactgctggg accaaggctaagaagtgcatctcctcccacctcagcacattggcagattttgccatcgag atgtttgatgtcctggatgagatcaactaccagtcttacaacgactttgtgctccgtgtt ggcatcaacgttggccctgtggtagctggagtgatcggggctcgcaggccgcagtatgac atttggggaaacacggtcaatgtggccagtcgcatggacagcaccggcgtccagggccgg atccaggtcacagaggaagttcaccggctgctgcggcggggttcctaccgcttcgtgtgc cgaggcaaagtcagtgtcaagggcaagggcgagatgctgacgtacttcctggaaggcagg accgatggaaatggctcccaaaccaggtccctgaactcagagcggaaaatgtgtccttat ggaagagctggcctccagaccagactggccgcgggccaccccctggtgcccccggcggcc ggcctcccagttggacctgggccagggactctgcagggctcggggcttgccccaggcccc ccaggccaacacctgcctcctggagcctctgggaaggaggcttag

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