KEGG   Cervus canadensis (wapiti): 122439577
Entry
122439577         CDS       T07554                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ccad  Cervus canadensis (wapiti)
Pathway
ccad00670  One carbon pool by folate
ccad00790  Folate biosynthesis
ccad01100  Metabolic pathways
ccad01240  Biosynthesis of cofactors
ccad01523  Antifolate resistance
ccad04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ccad00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    122439577 (DHFR)
   00670 One carbon pool by folate
    122439577 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    122439577 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    122439577 (DHFR)
Enzymes [BR:ccad01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     122439577 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 122439577
NCBI-ProteinID: XP_043320686
LinkDB
Position
4:29123358..29137981
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKDGNLPWPPLRNEFRYFQRMTTVSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPKGAHFLAKSLDDALELIEDPELTNKVDMVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDTFFPEIDFEKYKLLPEYPGVPLDVQEEKGIKYKF
EVYEKNN
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaactgcatcgtcgctgtgtcccagaacatgggcatcggcaaggac
gggaacctgccctggcctccactcagaaatgaattcaggtatttccaaagaatgactaca
gtctcttcagtagaaggtaaacagaatttggtgattatgggtaggaagacctggttctcc
attccagagaagaatcgacctttaaaggacagaattaacatagttctcagtagagaactc
aaggaacctccaaagggagctcattttcttgccaaaagtctggatgatgccttagaactt
attgaagatccagaattaacaaataaagtagacatggtttggatagtgggaggcagttct
gtttataaggaagccatgaacaagccaggccatcttagactatttgtgacaaggatcatg
caagaatttgaaagtgatacgtttttcccagaaattgattttgaaaaatataaacttctt
ccagaatacccaggtgttcccttggatgtccaggaggaaaaaggcattaagtacaaattt
gaagtatatgaaaagaacaattaa

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