Cervus canadensis (wapiti): 122440366 Help Entry 122440366         CDS       T07554                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism ccad  Cervus canadensis (wapiti) Pathway ccad04010   MAPK signaling pathway ccad04014   Ras signaling pathway ccad04015   Rap1 signaling pathway ccad04022   cGMP-PKG signaling pathway ccad04066   HIF-1 signaling pathway ccad04068   FoxO signaling pathway ccad04072   Phospholipase D signaling pathway ccad04081   Hormone signaling ccad04150   mTOR signaling pathway ccad04151   PI3K-Akt signaling pathway ccad04152   AMPK signaling pathway ccad04211   Longevity regulating pathway ccad04213   Longevity regulating pathway - multiple species ccad04520   Adherens junction ccad04910   Insulin signaling pathway ccad04913   Ovarian steroidogenesis ccad04923   Regulation of lipolysis in adipocytes ccad04930   Type II diabetes mellitus ccad04931   Insulin resistance ccad04932   Non-alcoholic fatty liver disease ccad04960   Aldosterone-regulated sodium reabsorption ccad05010   Alzheimer disease ccad05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ccad00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     122440366 (INSR)    04014 Ras signaling pathway     122440366 (INSR)    04015 Rap1 signaling pathway     122440366 (INSR)    04066 HIF-1 signaling pathway     122440366 (INSR)    04068 FoxO signaling pathway     122440366 (INSR)    04072 Phospholipase D signaling pathway     122440366 (INSR)    04022 cGMP-PKG signaling pathway     122440366 (INSR)    04151 PI3K-Akt signaling pathway     122440366 (INSR)    04152 AMPK signaling pathway     122440366 (INSR)    04150 mTOR signaling pathway     122440366 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     122440366 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     122440366 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122440366 (INSR)    04923 Regulation of lipolysis in adipocytes     122440366 (INSR)    04913 Ovarian steroidogenesis     122440366 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     122440366 (INSR)   09149 Aging    04211 Longevity regulating pathway     122440366 (INSR)    04213 Longevity regulating pathway - multiple species     122440366 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     122440366 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     122440366 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122440366 (INSR)    04932 Non-alcoholic fatty liver disease     122440366 (INSR)    04931 Insulin resistance     122440366 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ccad01001]     122440366 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:ccad04090]     122440366 (INSR) Enzymes [BR:ccad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      122440366 (INSR) Protein kinases [BR:ccad01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    122440366 (INSR) CD molecules [BR:ccad04090]  Proteins   122440366 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  122440366 NCBI-ProteinID:  XP_043322444 LinkDB All DBs Position 4:90827022..90968294 Genome browser AA seq 1382 aa AA seqDB search MGAGGRRGSAAVLLMVVVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCVPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPSRKRRALGDVGNVTAAIPTFLGF PNTSSTSTPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV SRRHYALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMESVPLDRSSHAQREEAGGRDGGSALGLKRNYDEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggccggcgggggtcggcagccgtgctgctgatggtggtcgtcgccgcg ctgctggtgggcgccgcgggccacctgtaccctggagaggtgtgccccggtatggatatc cggaataatctcacccggctgcatgagctggccaactgctcggtcattgaaggacatttg cagattctgttgatgttcaaaacaagacctgaggacttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatggactggagagcctgaag gacttgttccccaacctcacggtcatccgaggctcgcgcctcttctttaactatgcattg gtcatctttgagatggttcatctgaaggagcttggcctctacaacctgatgaacatcacc cggggttccgtccgcatcgagaagaacaatgaactctgctacctggccaccattgactgg tctcgcatcctggattccgtggaggataattacattgtgctgaacaaagatgacaatgag gagtgtggggacatttgtccaggcaccgccaagggcaagaccaactgccctgccactgtc atcaacgggcaatttgtggagcggtgctggacacacagccactgccagaaagtgtgtccg accatctgtaagtcacatggctgcacctctgagggtctctgctgccacagcgagtgcttg ggcaactgctcagagccagacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gacggcaggtgcgtggagacctgcccgcccccttactaccacttccaagactggcgctgc gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcaaggc tgccaccagtatgtcattcacaataacaagtgcgtccccgagtgcccctctggctacacg atgaattccagcaacttgatgtgtaccccttgcctgggcccctgtcccaaggtatgccac ctcctggaaggcgagaagaccatcgattcagtgacatctgcccaggagctccgtggctgc accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagccgag ctagaggccaaccttggactcattgaagaaatttcaggatatctgaaaatccgccggtcc tacgccctggtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg gaaattgggaactactctttctacgccttggacaaccagaacctaaggcaactatgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa ctctgcctgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag agaaatgacattgctctaaagaccaatggggaccaggcatcctgtgaaaatgaattactt aaattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtattgg cctcctgacttccgagacctcctggggttcatgctgttctacaaagaggccccttaccag aacgtgacagaattcgatgggcaggatgcgtgcggctccaatagctggacagtggtggat attgacccgcctacaaggtccaacgaccccaagtcacagaaccatcctgggtggctgatg cgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtcactttttct gatgaacgccgtacatacggggccaagagtgacatcatctatgtccagacagatgccact aatccttccgtgcccctggatcccatctcagtttctaactcctcatcccagattattctg aagtggaagcctccctccgaccccaatggcaatatcacacactacttggtgttctgggag aggcaggcggaagacagtgagctgtatgaactggattattgcctcaaagggttgaagctg ccctcccggacctggtctccgccgttcgaggcggaggggtcccagaagcacaaccagagt gagtatgaggaatctgctggcgaatgctgctcctgcccgaagaccgactctcagatcctc aaagagctggaggagtcctcgttcaggaagacgtttgaagactacctgcacaacgtggtt ttcatccccagaaaatcatcttcaggccctgttgccgaggacgctaggccatcaaggaaa cgcagagcccttggtgatgtggggaatgtgacagcggccatacccacctttctggggttc cccaatacctcctccaccagcacgcccacgagctcggaggagcacagacccttcgagaaa gtggtgaacaaggagtcgctggtcatctccggcctgcgtcactttactggctatcgcatc gagcttcaggcttgcaaccaagattctcccgaggagaggtgtagcgtggctgcctacgtc agcgccaggaccatgcctgaagccaaggcagacgatattgttggccccgtgacccatgaa atcttcgagaacaacgtcgttcacttgatgtggcaggagcccaaggaacccaatggcctg attgtgctgtatgaagtgagttatcgacgatacggcgaagaggagctgcacctctgcgtc tcccgccggcattatgctctggagcgcggttgccggttacgcgggctgccgcctggaaat tacagcgtgcgagttcgggccacgtccctggcaggcaacggatcttggacggaagccacc tatttctacgtgacagactatttagacgtgccatcaaatattgcaaaaatcatcatcggt cccctcatctttgtctttctcttcagtgttgtgattggaagtatttatctattcctgaga aagaggcagccagatgggccactgggaccactgtatgcttcttcaaacccagagtacctc agtgccagcgatgtatttccatgctctgtgtatgtgccggacgagtgggaggtgcctcga gagaagatcacgctcctgcgagaattggggcaaggctcctttggcatggtgtacgagggc aacgccagggacattgtcaagggtgaggcggagacccgtgtagcagtgaagacggtcaac gagtcggccagcctgcgagagcggatcgagtttctcaacgaggcttcggtcatgaagggc ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctg gtggtgatggagctgatggctcacggagacctgaagagttacctccgttccctgcggcct gaggctgagaataaccccggccgccctccccctaccctgcaagaaatgattcagatggcg gcagagatcgccgacgggatggcatacctgaacgctaagaagttcgtgcaccgggatctc gcagcccggaactgcatggtcgcccacgactttaccgtcaaaattggagacttcggaatg acaagagacatctatgaaacggattactaccggaaagggggcaaaggtctgctccccgtg cggtggatggcacctgaatccctgaaggacggagtcttcaccacctcttcggacatgtgg tcttttggtgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggtcta tcaaatgagcaggtgctgaaatttgtcatggatggagggtacctggatcaacctgacaat tgtccagagagagtcaccgacctgatgcggatgtgctggcaattcaaccccaagatgcgt ccgaccttcctggagatcgtggacctgctcaaggacgacctgcaccccagctttcctgaa gtgtccttcttccacagcgaggagaacaaggcgcccgagagcgaggagctggaaatggag tttgaggacatggagagcgtgcccctggaccggtcctcgcacgcgcagagagaggaggcc gggggccgggatggagggtcggcgctggggctaaagcgaaactatgacgagcacatcccc tacacccacatgaacgggggcaagaaaaatggacggattcttactctgccccggtcaaat ccttcctaa

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