Cervus canadensis (wapiti): 122446338
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Entry
122446338 CDS
T07554
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00590
Arachidonic acid metabolism
ccad01100
Metabolic pathways
ccad01523
Antifolate resistance
ccad04726
Serotonergic synapse
ccad04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
122446338 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
122446338 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
122446338 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122446338 (ALOX12)
Enzymes [BR:
ccad01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
122446338 (ALOX12)
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
122446338
NCBI-ProteinID:
XP_043332344
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Position
1:complement(33687706..33701662)
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AA seq
663 aa
AA seq
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MGHYRILVATGASLFAGSHNRVQLWLVGARGETELELQLRPARGQEEEFEHEVPEDLGPL
QFVKLRKHHSLVDDAWFCDRITVRGPGACEEAAFPCYRWVQGDGVLCLPEATARLAGNNA
LDVFQRHREKELKERHQIYRWATWKEGLPLTIAAGCEDDLPANMRFHEEKRLDFEWTLKA
GALEMVLKRVYTLLSSWTSLEDFDLIFWGQKSPLAEKVHQRWRDDELFGYQFLNGANPML
LRRCTSLPSRLVLPSGMEELRAQLERELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMDPSGKLLPMVIQIQPPSSISPTPPLFLPSDPPLAWLLAKTWVRNSDFQLHQLQYH
LLNTHLLAEVIAVATMRCLPGLHPIFKLLMPHIRYTMEINTRARTQLISDGGIFDKAVST
GGGGHVHLLRRALAQLTYRSLCPLDDLADRRLLGTPGALYACDALRLWEITARYVEGIVH
LFYRGDDVVKGDPELQAWCREITEVGLRQAQERGFPVSFQSQNQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATMMGSLPDVRQACLQMAITWHLGRR
QPDMVPLGHHKEKYFSDPKAKSVLNQFQTDLENLEREITARNEQLDLPYEYLKPSHIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccactaccgcatcctcgtggccaccggggcctcgctcttcgccggctcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaaacggagctggagctgcagctgcgg
ccggcgcggggccaggaggaggagtttgagcacgaagttccagaggacttggggccgctg
cagttcgtgaagttgcgcaaacaccactccctggtggacgacgcgtggttttgcgaccgc
atcacggtgcggggccctggagcctgcgaggaggccgcgttcccgtgctaccgctgggtg
cagggtgacggcgtgctgtgcctgccagaggccaccgcccgtctggcaggaaacaatgca
ttggacgtgttccagagacatcgagagaaggagctgaaagaaagacatcagatataccgc
tgggccacctggaaggaagggttacccctgacaatagctgcgggctgtgaggacgatcta
cctgcaaatatgagattccacgaggagaagaggctggactttgagtggacactgaaggcg
ggggctctggagatggtcctcaaacgtgtttacaccctcctgagctcctggaccagtctg
gaggattttgatctcatcttctggggccagaagagccccctggctgagaaggttcaccag
cgctggcgggacgatgagttgtttggctaccagttcctcaatggcgccaaccccatgctg
ttgagacgctgcacctctctgccctcccggctggtgctgccctcgggaatggaggagcta
cgggcccagctggagagagaactccagaatggttctctgtttgaggctgatttcatcctc
ctggacggaattccagccaacgtgatccgaggagagaagcagtacctggctgcccccctc
gtcatgctcaagatggaccccagtgggaagctgctacccatggtcatccagatccagcct
cccagctccatctccccgaccccaccactgttcctgccctcagatcctccactcgcctgg
ctcctggcaaagacctgggtccgaaattcagatttccaactgcatcagctccaataccat
ctgcttaacacccatctgctggctgaggtcattgctgtggccaccatgaggtgcctccca
gggctgcaccctatcttcaagctcctgatgccccacatccgctacacgatggaaatcaac
acccgggcacggactcagctcatctcagacggaggcatatttgataaagcagtgagcacc
ggtggagggggccatgtgcacttgctccgccgggccctggctcagctgacctaccgctcc
ctctgtcctcttgacgatctggctgatcgccgcctgctgggaaccccgggtgctctctat
gcctgtgatgctttacggctctgggaaatcactgcccggtatgtggaggggatcgtccac
ctcttctaccgcggggatgacgttgtgaaaggggaccctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgcgccaggcccaggagcgaggtttccctgtctccttccag
tcccagaatcaactctgccatttccttaccatgtgtgtcttcacgtgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggtccctaacgccccatgcaca
atgcggatgcccccacccaccaccaaggaagatgtgacaatggccacaatgatgggctca
ctacctgatgtccgacaagcctgtcttcaaatggccatcacatggcatctgggtcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaagtatttctcagaccccaaggcc
aagtctgtactaaaccaattccaaacagatctggaaaacttggaaagggaaattacagcc
cgcaatgagcaacttgacctgccttatgaatacctaaagcccagccacatagagaatagc
atcactatttga
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