Cervus canadensis (wapiti): 122447361 Help Entry 122447361         CDS       T07554                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism ccad  Cervus canadensis (wapiti) Pathway ccad04022   cGMP-PKG signaling pathway ccad04068   FoxO signaling pathway ccad04081   Hormone signaling ccad04140   Autophagy - animal ccad04152   AMPK signaling pathway ccad04211   Longevity regulating pathway ccad04213   Longevity regulating pathway - multiple species ccad04910   Insulin signaling pathway ccad04920   Adipocytokine signaling pathway ccad04923   Regulation of lipolysis in adipocytes ccad04930   Type II diabetes mellitus ccad04931   Insulin resistance ccad04932   Non-alcoholic fatty liver disease ccad04935   Growth hormone synthesis, secretion and action ccad05010   Alzheimer disease ccad05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:ccad00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     122447361 (IRS2)    04022 cGMP-PKG signaling pathway     122447361 (IRS2)    04152 AMPK signaling pathway     122447361 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     122447361 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     122447361 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122447361 (IRS2)    04923 Regulation of lipolysis in adipocytes     122447361 (IRS2)    04920 Adipocytokine signaling pathway     122447361 (IRS2)    04935 Growth hormone synthesis, secretion and action     122447361 (IRS2)   09149 Aging    04211 Longevity regulating pathway     122447361 (IRS2)    04213 Longevity regulating pathway - multiple species     122447361 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     122447361 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     122447361 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122447361 (IRS2)    04932 Non-alcoholic fatty liver disease     122447361 (IRS2)    04931 Insulin resistance     122447361 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  122447361 NCBI-ProteinID:  XP_043333891 LinkDB All DBs Position 9:2536854..2567270 Genome browser AA seq 1332 aa AA seqDB search MASPPEHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA GAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTRDE YFAVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPAAAATSGSCSASLPGALGGSAGAAA ADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVT LQLMSIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFE FRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSAC RVRTASEGDGGAAAAAGAGAGSGAAAAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGRA GKAALAPAGGGLQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPL HPQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRVYCGLRSNTPESIAETPPARDGSAG ELYGYMTMERPLSHCGGRAYRRVSGDGAPDLDRGLRKRTYSLTTPARQRPAPQPSSASLD EYTLMRATFSGSSGRLCPSCSASSPKVAYHPYPEDYGDVEIGSHRSSSSNLGADDGYVPM TPGVALLGAGSGSCKSDDYMPMSPTSVSAPKQILQPRPGPAALPPAGPAVPTPASAAGRA FPGTAGGYKTGSPAESSPEDSGYMRMWCGSKLSMESADSKLLPNGDYLNMSPSDAGTAGT PPDFFSAAGETLRGVPGYCYSSLPRSYKAPHACHGDSDQYVLMSSPVGRVLEEEPLEPAP GPAQASSAFPATAAGSGHPQPPLPAVPSPGRPGGGGGSRPDGFLAQRCRAVRPTRLSLEG LPALPRMHEYPLPPEPRSPGEYINIDFGEAGARLSPPAPPLLASAASSSSLLSASSPASS LGSGTPGTSGDSRQRSPLSDYMNLDFSSPKSPQPGAQGRDPVGSLDALLSPEASVYPPLP PRPAAPSSALQPPPPPPPPGELYRLPAATTSQGPGAASSSSSGTGDNGDYTEMAFGVAAT PPQPIAAPPKPDGARVSSPVSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADPQG GRRRHSSETFSSTTTVTPVSPSFAHTPKRHNSASVENVSLRKGSEGGCGGGLGGGDEPPS SPRQPPPTPQQARAWTPAQPGCSLVGCPGGNSSPMRRETSAGFQNGLNYIAIDVRDEPGL SPPLQQHPHGQTGDRSAWGRTRSLGGLISAVGAASPAGVCGGPGPGALPAANAYASIDFL THHLKEATVVKE NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccggagcacgggccccccgggccggcgggcggggacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg ggcgcgggcgggggcccggcgccgcagccgccgcggctcgagtactacgagagcgagaag aagtggcggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccagggacgag tacttcgccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcgggcgccggcgacgcgccccccgccgccgccgccacc tctgggtcctgcagcgcctccctgcccggcgccctgggcggctcggcgggcgccgccgcg gccgatgacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcag gtgaacctgaagcccaagggcctgggccagagcaagaacctgacgggcgtctaccgcctg tgcctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacg ctgcagctcatgagcatccgccgctgcggccactcggacagcttcttcttcatcgaggtg ggccgctccgccgtcacgggccccggcgagctgtggatgcaggcggacgactcggtggtg gcgcagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgag ttccggccgcgcagcaagagccagtcgtccggctcgtcggccacgcaccccatcagcgtg cccggcgcgcgccgccatcaccacttggtcaacctgcccccgagccagacggggctggtg cgccgctcgcgcaccgacagcctggccgccaccccgcccgccgccaagtgcagcgcgtgc cgggtgcgcacggccagcgagggcgacggcggcgcggcggcggcggcgggggccggggcg gggtccggggcggcggcggcggcgggcggcaggccggtgtcggtggcgggcagccccctg agcccgggcccggtgcgcgcgcctctgagccgctcgcacacgctgagcggcggccgcgcg ggcaaggcggcgctggcgccggcagggggcggcctgcagcacagccgctccatgtccatg cccgtggcgcactcgcccccggcggccaccagccccggcagcctgtcgtccagcagcggg cacggctcgggctcctacccgccgccccccggcccacacccgcacctgcagcaccccctg cacccccagcgcccctcgagcggcagcgcctcggcctcgggctcccccagcgaccccggc ttcatgtccttggacgagtatggctccagccccggggacctgagggtctactgcggcctc cggagcaacacgcccgagtccatcgccgagacgcccccggcgcgggatggcagcgcgggt gagctgtacggctacatgaccatggagaggccgctgagccactgcggcggccgcgcctac cgcagggtctctggggacggcgccccggacttggaccgagggctgaggaagcggacttac tcgctgaccacgcctgcccggcagcggccggcgccccagccgtcctccgcgtccctggac gagtacacgctgatgcgggccaccttctcgggcagctccggccgcctgtgcccgtcctgc agcgcgtcctctcccaaggtggcctaccacccgtaccccgaggactacggcgacgtcgag atcggctcgcaccgcagctctagcagtaatctgggcgcggacgacggctacgtgcccatg acccccggcgtggccctcctgggggcgggcagcgggagctgcaagagcgacgactatatg cccatgagccccaccagcgtgtcggccccgaagcagatcctgcagccacgccccgggcct gccgccttgccccctgcggggccagcggtgcccacgcccgcgtcggcagccggcagggcc ttcccgggcaccgcgggcggctacaagaccggctccccggccgagagctcccccgaggac agcgggtacatgcgcatgtggtgcggttccaagctgtccatggagagcgccgacagcaag ctgctgcccaacggggactacctcaacatgtcccccagcgacgcgggcaccgcgggcacc ccgcccgacttcttctctgctgcgggggagactctgcggggcgtgcccggctactgctac agctccctgccccgctcctacaaggccccccacgcctgccacggcgacagcgaccagtac gtgctcatgagctcgcccgtgggccgggtcttggaggaggagccgctggagccggccccc ggccccgcgcaggcgtccagtgccttcccggccacggcggctggcagcggccacccccag ccacccctccccgccgtgccttcgcctgggaggccaggcggtggcggaggtagccgcccc gacggcttcctggctcagcgctgccgggcagtgcggcccacgcgcctgtctctggagggg ctgccggccctgccccgcatgcacgagtacccgctgccccccgaacccaggagtccaggc gagtacatcaacatcgacttcggggaggccggcgcgcgcctgtcgccgcccgcgcccccg ctcctggcctcggccgcctcctcgtcgtcgctgctgtccgccagcagcccggcctcgtcc ctgggctccggcaccccgggcacgagtggggacagccggcagcgctccccgctctccgac tacatgaacctcgacttcagctcgcccaagtcgccgcagccgggcgcccagggccgggac cccgtgggctccttggacgctctgctgtccccagaggcctccgtgtacccgccgctgccc cctcgcccggccgctccctcctcggccctgcagccgccacccccgccgcccccaccgggc gagctgtaccgcctgcctgcggcaaccacctcccagggcccaggcgcggcctcctcctcg tcctcgggcacgggggacaacggtgactacaccgagatggccttcggcgtggccgccacc ccgccgcaaccgatcgctgcgcccccgaagcccgacggtgcccgcgtgagcagccccgtg tccggcctcaagaggctgagcctcatggatcaggtgtcgggggtcgaggccttcctgcag gccggccagcccccagacccgcaccggggggccaaggtcatccgcgcggacccgcagggg ggccgtcgtcgccacagctccgagaccttctcctcgaccaccactgtgacccccgtgtcc ccgtcctttgctcacacccccaagcgtcacaactcggcctcggtggagaacgtttctctc aggaaaggcagcgaagggggctgcggcggcggcctgggtgggggcgacgagcccccctcg tcgccgcgccagcccccgccgacgccgcagcaggcgcgggcctggacgccggctcagccc ggctgcagcctggtcggctgtcccgggggcaacagttcgcccatgcgccgggagacgtcc gccggcttccagaatggcctcaactacatcgccatcgacgtgagggacgagccggggctg tcaccgcccctgcagcagcacccacacgggcagacgggcgacaggagcgcctggggccgc acccggagcctcgggggtctcatcagcgccgtgggcgctgccagccccgccggggtgtgc ggggggccaggccccggtgctctgcccgcggccaacgcctacgccagcatcgacttcttg acgcatcacctgaaagaggccacggtggtgaaagagtga

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